生物物理
The cellular-level process of ion transport is known to generate a magnetic field. A non-invasive magnetoencephalography (MEG) technique was used to measure the magnetic field emanating from HeLa, HEK293 and H9c2(2-1) rat cardiac cells. The…
The movement of organisms and cells can be governed by occasional long distance runs, according to an approximate L\'evy walk. For T cells migrating through chronically-infected brain tissue, runs are further interrupted by long pauses, and…
Active fluids refer to the fluids that contain self-propelled particles such as bacteria or micro-algae, whose properties differ fundamentally from the passive fluids. Such particles often exhibit an intermittent motion, with high-motility…
We study the clustering of a model cyanobacterium \textit{Synechocystis} into microcolonies. The bacteria are allowed to diffuse onto surfaces of different hardness, and interact with the others by aggregation and detachment. We find that…
In this paper we consider a biased velocity jump process with excluded-volume interactions for chemotaxis, where we account for the size of each particle. Starting with a system of N individual hard rod particles in one dimension, we derive…
We measured the effective diffusion coefficient in regions of microfluidic networks of controlled geometry using the FRAP (Fluorescence Recovery After Photobleaching) technique. The geometry of the networks was based on Voronoi…
We investigate the possible influence of poly unsaturated fatty acids (PUFAs) in the lipid bilayer of cell membranes on the conduction properties of the selectivity filter of voltage gated ion channels. Any change of this conductivity can…
We investigate diffusive search on planar networks, motivated by tubular organelle networks in cell biology that contain molecules searching for reaction partners and binding sites. Exact calculation of the diffusive mean first-passage time…
The formation of biomolecular condensates inside cells often involve intrinsically disordered proteins (IDPs), and several of these IDPs are also capable of forming droplet-like dense assemblies on their own, through liquid-liquid phase…
The formation of protein patterns inside cells is generically described by reaction-diffusion models. The study of such systems goes back to Turing, who showed how patterns can emerge from a homogenous steady state when two reactive…
We present a new acquisition method that enables high-resolution, fine-detail full reconstruction of the three-dimensional movement and structure of individual human sperm cells swimming freely. We achieve both retrieval of the…
The isomerisation of azo dyes can induce conformational change which have potential applications in medicine and environmental protection. We developed an agar diffusion assay to test the capture and release of biologically active molecules…
The reliable detection of environmental molecules in the presence of noise is an important cellular function, yet the underlying computational mechanisms are not well understood. We introduce a model of two interacting sensors which allows…
In this study, we investigate a porous medium-type flux limited reaction--diffusion equation that arises in morphogenesis modeling. This nonlinear partial differential equation is an extension of the generalized…
Sheep are gregarious animals, and they often aggregate into dense, cohesive flocks, especially under stress. In this paper, we use image processing tools to analyze a publicly available aerial video showing a dense sheep flock moving under…
Magnetic resonance spectroscopy of single biomolecules under near-physiological conditions may substantially advance understanding of biological function, yet remains very challenging. Here we use nitrogen-vacancy centers in diamonds to…
Magnetic resonance imaging (MRI) is a non-invasive and label-free technique widely used in medical diagnosis and life science research, and its success has benefited greatly from continuing efforts on enhancing contrast and resolution. Here…
Sperm cell motility and morphology observed under the bright field microscopy are the only criteria for selecting particular sperm cell during Intracytoplasmic Sperm Injection (ICSI) procedure of Assisted Reproductive Technology (ART).…
Early recordings of nervous conduction revealed a notable thermal signature associated with the electrical signal. The observed production and subsequent absorption of heat arise from physicochemical processes that occur at the cell…
There is mounting empirical evidence that many communities of living organisms display key features which closely resemble those of physical systems at criticality. We here introduce a minimal model framework for the dynamics of a community…