Single DNA Electron Spin Resonance Spectroscopy in Aqueous Solutions

Fazhan Shi; Fei Kong; Pengju Zhao; Xiaojun Zhang; Ming Chen; Sanyou Chen; Qi Zhang; Mengqi Wang; Xiangyu Ye; Zhecheng Wang; Zhuoyang Qin; Xing Rong; Jihu Su; Pengfei Wang; Peter Z. Qin; Jiangfeng Du

doi:10.1038/s41592-018-0084-1

Single DNA Electron Spin Resonance Spectroscopy in Aqueous Solutions

Biological Physics 2020-02-21 v1 Quantum Physics

Authors: Fazhan Shi , Fei Kong , Pengju Zhao , Xiaojun Zhang , Ming Chen , Sanyou Chen , Qi Zhang , Mengqi Wang , Xiangyu Ye , Zhecheng Wang , Zhuoyang Qin , Xing Rong , Jihu Su , Pengfei Wang , Peter Z. Qin , Jiangfeng Du

View on arXiv ↗ PDF ↗ DOI ↗

Abstract

Magnetic resonance spectroscopy of single biomolecules under near-physiological conditions may substantially advance understanding of biological function, yet remains very challenging. Here we use nitrogen-vacancy centers in diamonds to detect electron spin resonance spectra of individual, tethered DNA duplexes labeled with a nitroxide spin label in aqueous buffer solutions at ambient temperatures. This paves the way for magnetic resonance studies on single biomolecules and their inter-molecular interactions in a native-like environment.

Keywords

nitrogen-vacancy centers in diamond magnetic resonance dna biophysics

Cite

@article{arxiv.2002.08425,
  title  = {Single DNA Electron Spin Resonance Spectroscopy in Aqueous Solutions},
  author = {Fazhan Shi and Fei Kong and Pengju Zhao and Xiaojun Zhang and Ming Chen and Sanyou Chen and Qi Zhang and Mengqi Wang and Xiangyu Ye and Zhecheng Wang and Zhuoyang Qin and Xing Rong and Jihu Su and Pengfei Wang and Peter Z. Qin and Jiangfeng Du},
  journal= {arXiv preprint arXiv:2002.08425},
  year   = {2020}
}

Comments

22 pages, 14 figures

Single DNA Electron Spin Resonance Spectroscopy in Aqueous Solutions

Abstract

Keywords

Cite

Comments

Related papers