中文

Cannings模型中的Haldane公式:中等弱选择情形

概率论 2022-01-19 v4

摘要

我们通过paintbox构造引入带方向性选择的Cannings模型,并在离散时间下与新提出的\emph{Cannings祖先选择图}的线计数过程建立强对偶性。该对偶性也给出了有益类型固定概率的公式。Haldane公式指出,在大小为 NN 的单倍体种群中,单个选择性有利个体固定的概率渐近(当 NN\to \infty 时)等于单倍体的选择优势 sNs_N 除以后代方差的一半。对于Kingman吸引内的一类后代分布,我们证明了当序列 sNs_N 满足 N1sNN1/2N^{-1} \ll s_N \ll N^{-1/2} (即“中等弱选择”机制)时的该渐近性。结果表明,对于 sNN2/3 s_N \ll N^{-2/3} ,Cannings祖先选择图与Moran模型的祖先选择图极为接近,以至于合适的耦合论证可将问题渐近地归约为Moran模型中可显式计算的固定概率。

关键词

引用

@article{arxiv.1907.10049,
  title  = {Haldane's formula in Cannings models: The case of moderately weak selection},
  author = {Florin Boenkost and Adrián González Casanova and Cornelia Pokalyuk and Anton Wakolbinger},
  journal= {arXiv preprint arXiv:1907.10049},
  year   = {2022}
}

备注

Minor revision of the former version. In particular, we made the following changes: Condition (3.8) in this version is slightly weaker than Condition (3.9) in the former version. The proof of Theorem 3.5b remained essentially the same. The former Section 4 is now part of Section 2 (Section 2.4). Lemma 6.3 and 6.4 are interchanged, now Lemma 5.4 and 5.3