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Polymer translocation has long been a topic of interest in the field of biological physics given its relevance in both biological (protein and DNA/RNA translocation through nuclear and cell membranes) and technological processes (nanopore…

Soft Condensed Matter · Physics 2023-09-11 Alejandro Sainz-Agost , Fernando Falo , Alessandro Fiasconaro

We suggest a theoretical description of the force-induced translocation dynamics of a polymer chain through a nanopore. Our consideration is based on the tensile (Pincus) blob picture of a pulled chain and the notion of propagating front of…

Soft Condensed Matter · Physics 2012-04-17 J. L. A. Dubbeldam , V. G. Rostiashvili , A. Milchev , T. A. Vilgis

We develop a theory for polymer translocation driven by a time-dependent force through an oscillating nanopore. To this end, we extend the iso-flux tension propagation theory (IFTP) [Sarabadani \textit{et al., J. Chem. Phys.}, 2014,…

Statistical Mechanics · Physics 2015-09-02 Jalal Sarabadani , Timo Ikonen , Tapio Ala-Nissila

DNA translocation through nanopores is one of the most promising strategies for the next-generation sequencing technologies. Most part of experimental and numerical works has focused on polymer translocation biased by electrophoresis, where…

Soft Condensed Matter · Physics 2018-02-07 Timothée Menais

We consider single particle and polymer translocation where the frictional properties experienced from the environment are changing in time. This work is motivated by the interesting frequency responsive behaviour observed when a polymer is…

Soft Condensed Matter · Physics 2012-12-06 Jack A. Cohen , Abhishek Chaudhuri , Ramin Golestanian

The transport of polymers with folded configurations across membrane pores is investigated theoretically by analyzing simple discrete stochastic models. The translocation dynamics is viewed as a sequence of two events: motion of the folded…

Statistical Mechanics · Physics 2009-11-13 Stanislav Kotsev , Anatoly B. Kolomeisky

We study the driven translocation of a flexible polymer through an interacting conical pore using Langevin dynamics simulations. We find that, for a fixed value of externally applied force and pore polymer interaction strength, the mean…

Soft Condensed Matter · Physics 2021-02-17 Rajneesh Kumar , Abhishek Chaudhuri , Rajeev Kapri

We study the passage (translocation) of a self-avoiding polymer through a membrane pore in two dimensions. In particular, we numerically measure the probability distribution Q(T) of the translocation time T, and the distribution P(s,t) of…

Statistical Mechanics · Physics 2009-02-12 Clément Chatelain , Yacov Kantor , Mehran Kardar

We investigate the translocation of stiff polymers in the presence of binding particles through a nanopore by two-dimensional Langevin dynamics simulations. We find that the mean translocation time shows a minimum as a function of the…

Soft Condensed Matter · Physics 2015-06-12 Wancheng Yu , Yiding Ma , Kaifu Luo

Using analytical techniques and Langevin dynamics simulations, we investigate the dynamics of polymer translocation through a nanochannel embedded in two dimensions under an applied external field. We examine the translocation time for…

Soft Condensed Matter · Physics 2012-03-26 Huaisong Yong , Yilin Wang , Shichen Yuan , Bi Xu , Kaifu Luo

We study the driven translocation of polymers under time-dependent driving forces using $N$-particle Langevin dynamics simulations. We consider the force to be either sinusoidally oscillating in time or dichotomic noise with exponential…

Soft Condensed Matter · Physics 2015-06-12 Timo Ikonen , Jaeoh Shin , Tapio Ala-Nissila , Wokyung Sung

We study the dynamics of the passage of a polymer through a membrane pore (translocation), focusing on the scaling properties with the number of monomers $N$. The natural coordinate for translocation is the number of monomers on one side of…

Soft Condensed Matter · Physics 2009-11-07 Jeffrey Chuang , Yacov Kantor , Mehran Kardar

Most of the theoretical models describing the translocation of a polymer chain through a nanopore use the hypothesis that the polymer is always relaxed during the complete process. In other words, models generally assume that the…

Biomolecules · Quantitative Biology 2009-11-13 Michel G. Gauthier , Gary W. Slater

Brownian dynamics (BD) simulations are used to study the translocation dynamics of a coarse-grained polymer through a cylindrical nanopore. We consider the case of short polymers, with a polymer length, N, in the range N=21-61. The rate of…

Soft Condensed Matter · Physics 2015-06-18 James M. Polson , Taylor Dunn

We investigate the translocation dynamics of a folded linear polymer which is pulled through a nanopore by an external force. To this end, we generalize the iso-flux tension propagation (IFTP) theory for end-pulled polymer translocation to…

Soft Condensed Matter · Physics 2019-12-18 Bappa Ghosh , Jalal Sarabadani , Srabanti Chaudhury , Tapio Ala-Nissila

We study the driven translocation of a semi-flexible polymer through a nanopore by means of a modified version of the iso-flux tension propagation theory (IFTP), and extensive molecular dynamics (MD) simulations. We show that in contrast to…

Soft Condensed Matter · Physics 2016-12-28 Jalal Sarabadani , Timo Ikonen , Harri Mökkönen , Tapio Ala-Nissila , Spencer Carson , Meni Wanunu

We consider the translocation of a one-dimensional polymer through a pore channel helped by a motor driven by a dichotomous noise with time exponential correlation. We are interested in the study of the translocation time, mean velocity and…

Soft Condensed Matter · Physics 2012-03-01 Alessandro Fiasconaro , Juan José Mazo , Fernando Falo

Polymer translocation through a nano-pore in a thin membrane is studied using a coarse-grained bead-spring model and Langevin dynamics simulation with a particular emphasis to explore out of equilibrium characteristics of the translocating…

Soft Condensed Matter · Physics 2015-05-14 Aniket Bhattacharya , Kurt Binder

We study the translocation dynamics of a polymer chain threaded through a nanopore by an external force. By means of diverse methods (scaling arguments, fractional calculus and Monte Carlo simulation) we show that the relevant dynamic…

Statistical Mechanics · Physics 2007-07-29 J. L. A. Dubbeldam , A. Milchev , V. G. Rostiashvili , T. A. Vilgis

We construct a new statistical physical model of polymer translocation through a pore in a membrane treated as the diffusion process across a free energy barrier. We determine the translocation time in terms of chain flexibility yielding an…

Soft Condensed Matter · Physics 2015-06-25 W. Sung , P. J. Park