English

Translocation of stiff polymers through a nanopore driven by binding particles

Soft Condensed Matter 2015-06-12 v1 Statistical Mechanics Biological Physics Biomolecules

Abstract

We investigate the translocation of stiff polymers in the presence of binding particles through a nanopore by two-dimensional Langevin dynamics simulations. We find that the mean translocation time shows a minimum as a function of the binding energy ϵ\epsilon and the particle concentration ϕ\phi, due to the interplay of the force from binding and the frictional force. Particularly, for the strong binding the translocation proceeds with a decreasing translocation velocity induced by a significant increase of the frictional force. In addition, both ϵ\epsilon and ϕ\phi have an notable impact on the distribution of the translocation time. With increasing ϵ\epsilon and ϕ\phi, it undergoes a transition from an asymmetric and broad distribution under the weak binding to a nearly Gaussian one under the strong binding, and its width becomes gradually narrower.

Keywords

Cite

@article{arxiv.1212.1055,
  title  = {Translocation of stiff polymers through a nanopore driven by binding particles},
  author = {Wancheng Yu and Yiding Ma and Kaifu Luo},
  journal= {arXiv preprint arXiv:1212.1055},
  year   = {2015}
}

Comments

7 pages, 6 figures, accepted to J. Chem. Phys