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The control over DNA elongation in nanofluidic devices holds great potential for large-scale genomic analysis. So far, the manipulation of DNA in nanochannels has been mostly carried out with electrophoresis and seldom with hydrodynamics,…

Water, a subject of human fascination for millennia, is likely the most studied substance on Earth, with an entire scientific field -- hydrodynamics -- dedicated to understanding water in motion. However, when water flows through…

软凝聚态物质 · 物理学 2025-08-19 Maxim Trushin , Daria V. Andreeva , Francois M. Peeters , Kostya S. Novoselov

We study the time evolution and driven motion of thin liquid films lying on top of chemical patterns on a substrate. Lattice-Boltzmann and molecular dynamics methods are used for simulations of the flow of microscopic and nanoscopic films,…

软凝聚态物质 · 物理学 2012-04-04 Fabian Dörfler , Markus Rauscher , Joel Koplik , Jens Harting , S. Dietrich

We studied the electrical conductivity of DNA molecules with conducting atomic force microscopy as a function of the chemical nature of the substrate surfaces, the nature of the electrical contact, and the number of DNA molecules (from a…

材料科学 · 物理学 2009-11-10 Thomas Heim , Dominique Deresmes , Dominique Vuillaume

Nanometer-sized columns of condensed water molecules are created by an atomic-resolution force microscope operated in ambient conditions. Unusual stepwise decrease of the force gradient associated with the thin water bridge in the…

流体动力学 · 物理学 2009-11-11 H. Choe , M. -H. Hong , Y. Seo , K. Lee , G. Kim , Y. Cho , J. Ihm , and W. Jhe

Mirroring their role in electrical and optical physics, two-dimensional crystals are emerging as novel platforms for fluid separations and water desalination, which are hydrodynamic processes that occur in nanoscale environments. For…

统计力学 · 物理学 2016-05-11 Steven E. Strong , Joel D. Eaves

A multiscale approach is used to simulate the translocation of DNA through a nanopore. Within this scheme, the interactions of the molecule with the surrounding fluid (solvent) are explicitly taken into account. By generating polymers of…

生物物理 · 物理学 2009-11-13 Simone Melchionna , Maria Fyta , Efthimios Kaxiras , Sauro Succi

We have managed to correlate the stability constants of complex formation, which can be registered in equilibrium state, to the dynamic characteristic of the complex lifetime. Thus, the principal concept of molecular biophysics regarding…

The description of hydrodynamic interactions between a particle and the surrounding liquid, down to the nanometer scale, is of primary importance since confined liquids are ubiquitous in many natural and technological situations. In this…

Molecular dynamics simulations of dense and rarefied fluids comprising small chain molecules in chemically patterned nano-channels predict a novel switching from Poiseuille to plug flow along the channel. We also demonstrate behavior akin…

软凝聚态物质 · 物理学 2009-11-11 Marek Cieplak , Joel Koplik , Jayanth R. Banavar

DNA is now firmly established as a versatile and robust platform for achieving synthetic nanostructures. While the folding of single molecules into complex structures is routinely achieved through engineering basepair sequences, much less…

软凝聚态物质 · 物理学 2025-05-15 Soumen De Karmakar , Thomas Speck

Continuum simulation is employed to study ion transport and fluid flow through a nanopore in a solid-state membrane under an applied potential drop. Results show the existence of concentration polarization layers on the surfaces of the…

流体动力学 · 物理学 2015-06-16 Mao Mao , Sandip Ghosal , Guohui Hu

We investigate the behavior of a one-dimensional diatomic fluid under a shock wave excitation. We find that the properties of the resulting shock wave are in striking contrast with those predicted by hydrodynamic and kinetic approaches,…

统计力学 · 物理学 2009-11-11 Pablo I. Hurtado

Molecular dynamics studies of nono-sized rigid grains, droplets and bubbles in nano-sized pores indicate that the drag force may have a hydrodynamic form if the moving object is dense and small compared to the pore diameter. Otherwise, the…

统计力学 · 物理学 2009-11-07 Nazar Sushko , Marek Cieplak

Chemically patterned surfaces are of significant interest in the context of microfluidic applications. Miniaturization of such devices will eventually lead to structures on the nano-scale. Whereas on the micron scale purely macroscopic…

软凝聚态物质 · 物理学 2007-05-23 Markus Rauscher , S. Dietrich

Water plays a key role in biological membrane transport. In ion channels and water-conducting pores (aquaporins), one dimensional confinement in conjunction with strong surface effects changes the physical behavior of water. In molecular…

生物物理 · 物理学 2019-07-02 Oliver Beckstein , Mark S. P. Sansom

The coarse-grained molecular dynamics (MD) or Brownian dynamics (BD) simulation is a particle-based approach that has been applied to a wide range of biological problems that involve interactions with surrounding fluid molecules or the…

软凝聚态物质 · 物理学 2014-11-20 Szu-Pei Fu , Yuan-Nan Young , Shidong Jiang

We introduce a method for analyzing the physical properties of nanoparticles in fluids via the competition between viscous drag and optical forces. By flowing particles through a microfluidic device containing an optical microcavity which…

光学 · 物理学 2021-12-01 Kiana Malmir , William Okell , Aurélien A P Trichet , Jason M Smith

Nanofluidics has firmly established itself as a new field in fluid mechanics, as novel properties have been shown to emerge in fluids at the nanometric scale. Thanks to recent developments in fabrication technology, artificial nanofluidic…

流体动力学 · 物理学 2020-12-01 Nikita Kavokine , Roland R. Netz , Lydéric Bocquet

The internal motions of DNA immersed in bio-fluid are investigated. The interactions between the fragments of DNA and the surrounding bio-fluid are modeled using the gauge fluid lagrangian. In the model, the bio-fluid is coupled to the…

生物物理 · 物理学 2010-12-14 A. Sulaiman , L. T. Handoko
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