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A new method is introduced for analysis of interactions between time-dependent coupled oscillators, based on the signals they generate. It distinguishes unsynchronized dynamics from noise-induced phase slips, and enables the evolution of…

数据分析、统计与概率 · 物理学 2012-08-09 Tomislav Stankovski , Andrea Duggento , Peter V. E. McClintock , Aneta Stefanovska

Isolated post-capillary pulmonary hypertension (Ipc-PH) occurs due to left heart failure, which contributes to 1 out of every 9 deaths in the United States. In some patients, through unknown mechanisms, Ipc-PH transitions to combined…

组织与器官 · 定量生物学 2021-03-11 Michelle A. Bartolo , M. Umar Qureshi , Mitchel J. Colebank , Naomi C. Chesler , Mette S. Olufsen

Arrhythmias are potentially fatal disruptions to the normal heart rhythm, but their underlying dynamics is still poorly understood. Theoretical modeling is an important tool to fill this gap. Typical studies often employ detailed…

组织与器官 · 定量生物学 2022-03-08 R. V. Stenzinger , M. H. R. Tragtenberg

Continuous blood pressure (BP) monitoring is essential for timely diagnosis and intervention in critical care settings. However, BP varies significantly across individuals, this inter-patient variability motivates the development of…

机器学习 · 计算机科学 2024-09-10 Cheng Wan , Chenjie Xie , Longfei Liu , Dan Wu , Ye Li

Cardiac alternans, a beat-to-beat alternation in action potential duration (at the cellular level) or in ECG morphology (at the whole heart level), is a marker of ventricular fibrillation, a fatal heart rhythm that kills hundreds of…

生物物理 · 物理学 2009-11-13 Xiaopeng Zhao

Heart rate variability (HRV) series reflects the dynamical variation of heartbeat-to-heartbeat intervals in time and is one of the outputs of the cardiovascular system. Over the years, this system has been recognized for generating…

信号处理 · 电气工程与系统科学 2024-04-18 M. Bianco , A. Scarciglia , C. Bonanno , G. Valenza

In type I intermittency, simple models known for at least twenty years show that a characteristic u-shaped probability distribution is obtained for the laminar phase length. We have shown elsewhere that, for some cases of pathology, the…

混沌动力学 · 物理学 2007-05-23 J. J. Zebrowski , R. Baranowski

Cardiovascular diseases (CVDs) encompass a group of disorders affecting the heart and blood vessels, including conditions such as coronary artery disease, heart failure, stroke, and hypertension. In cardiovascular diseases, heart failure is…

人工智能 · 计算机科学 2024-07-12 Ershadul Haque , Manoranjan Paul , Faranak Tohidi

This work presents an algorithm for determining the parameters of a nonlinear dynamic model of the respiratory system in patients undergoing assisted ventilation. Using the pressure and flow signals measured at the mouth, the model's…

系统与控制 · 电气工程与系统科学 2024-03-01 Diego A. Riva , Carolina A. Evangelista , Paul F. Puleston , Luis Corsiglia , Nahuel Dargains

The rhythmic pumping motion of the heart stands as a cornerstone in life, as it circulates blood to the entire human body through a series of carefully timed contractions of the individual chambers. Changes in the size, shape and movement…

"Mayer waves" are long-period (6 to 12 seconds) oscillations in arterial blood pressure, which have been observed and studied for more than 100 years in the cardiovascular system of humans and other mammals. A mathematical model of the…

动力系统 · 数学 2008-02-03 Roselyn M. Abbiw-Jackson , William Langford

Irregular multivariate time series with missing values present significant challenges for predictive modeling in domains such as healthcare. While deep learning approaches often focus on temporal interpolation or complex architectures to…

机器学习 · 计算机科学 2026-03-16 Dingyi Nie , Yixing Wu , C. -C. Jay Kuo

In the field of cardio-thoracic surgery, valve function is monitored over time after surgery. The motivation for our research comes from a study which includes patients who received a human tissue valve in the aortic position. These…

Transitions in the dynamics of complex systems can be characterized by changes in the synchronization behavior of their components. Taking the human cardio-respiratory system as an example and using an automated procedure for screening the…

数据分析、统计与概率 · 物理学 2009-11-13 Ronny Bartsch , Jan W. Kantelhardt , Thomas Penzel , Shlomo Havlin

The classic heuristic formula for calculating the mean arterial blood pressure (MAP) in the human cardiac cycle using 1/3 of the systolic pressure (P_S) plus 2/3 of the diastolic pressure (P_D) importantly neglects the nonlinear effect of…

组织与器官 · 定量生物学 2025-04-01 Maximilian Nguyen

Patients at high risk for sudden death often exhibit complex heart rhythms in which abnormal heartbeats are interspersed with normal heartbeats. We analyze such a complex rhythm in a single patient over a 12-hour period and show that the…

- Modeling Human cardiovascular system is always an important issue. One of the most effective methods is using lumped model to reach to a complete model of human cardiovascular system. Such modeling with advanced considerations is used in…

Experiments that discuss influence of noise to H. Seidel and H. Herzel dynamics model of human cardiovascular system are presented. Noise is introduced by considering stochastic delays in response to the sympathetic system. It appears that…

组织与器官 · 定量生物学 2007-05-23 Aleksandra Dudkowska , Danuta Makowiec

The paper deals with the estimation of a signal model in the form of the output of a continuous linear time-invariant system driven by a sequence of instantaneous impulses, i.e. an impulsive time series. This modeling concept arises in,…

系统与控制 · 电气工程与系统科学 2023-04-27 Håkan Runvik , Alexander Medvedev

Signal-based early detection of illnesses has been a key topic in research and hospital settings; it reduces technological costs and paves the way for quick and effective patient-care operations. Elementary machine learning and signal…

其他定量生物学 · 定量生物学 2020-11-04 Camille Dunning