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We introduce a multi-species lattice gas model for motor protein driven collective cargo transport on cellular filaments. We use this model to describe and analyze the collective motion of interacting vesicle cargoes being carried by…

统计力学 · 物理学 2010-09-10 Sudipto Muhuri , Ignacio Pagonabarraga

Phenotypic variation is a hallmark of cellular physiology. Metabolic heterogeneity, in particular, underpins single-cell phenomena such as microbial drug tolerance and growth variability. Much research has focussed on transcriptomic and…

分子网络 · 定量生物学 2019-01-31 Mona K. Tonn , Philipp Thomas , Mauricio Barahona , Diego A Oyarzún

Long, flexible fibers transported by a turbulent channel flow sample non-linear variations of the fluid velocity along their length. As the fibers tumble and collide with the boundaries, they bounce off with an impulse that propels them…

流体动力学 · 物理学 2023-04-20 Jeremie Bec , Christophe Brouzet , Christophe Henry

Suspensions of swimming micro-organisms provide examples of coordinated active dynamics. That has stimulated the study of a phenomenological theory combining synchronization and polar order in active matter. Here, we consider another…

软凝聚态物质 · 物理学 2019-04-08 M. Leoni

Locally broken symmetries are used across fields to transport matter, particles and information in preferential directions. Beyond local mechanisms, spatially distributed nonlinearities in crystalline media have enabled non-reciprocal…

软凝聚态物质 · 物理学 2026-03-31 Aaron Winn , Justine Parmentier , Eleni Katifori , Martin Brandenbourger

Molecules with complex internal structure in time-dependent periodic potentials are studied by using short Rubinstein-Duke model polymers as an example. We extend our earlier work on transport in stochastically varying potentials to cover…

统计力学 · 物理学 2015-05-18 Janne Kauttonen , Juha Merikoski

In two-dimensional electron systems, plasmons are gapless and long-lived collective excitations of propagating charge density oscillations. We study the fluctuation mechanism of plasmon-assisted transport in the regime of electron…

介观与纳米尺度物理 · 物理学 2023-12-15 Dmitry Zverevich , Alex Levchenko

The transport of biomolecules across a cell membrane is an important phenomena that plays a pivotal role in the functioning of biological cells. In this paper, we investigate such processes by modeling the translocation of polymers through…

软凝聚态物质 · 物理学 2022-11-01 Andri Sharma

Many natural and industrial processes rely on constrained transport, such as proteins moving through cells, particles confined in nanocomposite materials or gels, individuals in highly dense collec- tives and vehicular traffic conditions.…

The propulsion of active particles by self-diffusiophoresis is driven by asymmetric catalytic reactions on the particle surface that generate a mechanochemical coupling between the fluid velocity and the concentration fields of fuel and…

统计力学 · 物理学 2018-12-24 Pierre Gaspard , Raymond Kapral

We propose a stochastic process wherein molecular transport is mediated by asymmetric nucleation of domains on a one-dimensional substrate. Track-driven mechanisms of molecular transport arise in biophysical applications such as Holliday…

统计力学 · 物理学 2009-11-13 Amit Lakhanpal , Tom Chou

The Notch-Delta signaling pathway mediates cell differentiation implicated in many regulatory processes including spatiotemporal patterning in tissues by promoting alternate cell fates between neighboring cells. At the multicellular level,…

细胞行为 · 定量生物学 2022-10-12 Madeline Galbraith , Federico Bocci , José N. Onuchic

Quantum mechanical motion of a particle in a periodic asymmetric potential is studied theoretically at zero temperature. It is shown based on semi-classical approximation that the tunneling probability from one local minimum to the next…

统计力学 · 物理学 2009-10-30 Gen Tatara , Macoto Kikuchi , Satoshi Yukawa , Hiroshi Matsukawa

We study the dynamics of asymmetric, deformable particles in oscillatory, linear shear flow. By simulating the motion of a dumbbell, a ring polymer, and a capsule we show that cross-stream migration occurs for asymmetric elastic particles…

软凝聚态物质 · 物理学 2017-04-26 Matthias Laumann , Paul Bauknecht , Stephan Gekle , Diego Kienle , Walter Zimmermann

We use numerical simulations to examine two-dimensional particle mixtures that strongly phase separate in equilibrium. When the system is externally driven in the presence of quenched disorder, plastic flow occurs in the form of meandering…

统计力学 · 物理学 2009-11-13 A. Libal , C. Reichhardt , C. J. Olson Reichhardt

Gas permeation through nanoscale pores is ubiquitous in nature and plays an important role in a plethora of technologies. Because the pore size is typically smaller than the mean free path of gas molecules, their flow is conventionally…

介观与纳米尺度物理 · 物理学 2018-06-25 A. Keerthi , A. K. Geim , A. Janardanan , A. P. Rooney , A. Esfandiar , S. Hu , S. A. Dar , I. V. Grigorieva , S. J. Haigh , F. C. Wang , B. Radha

Many unicellular organisms allocate their key proteins asymmetrically between the mother and daughter cells, especially in a stressed environment. A recent theoretical model is able to predict when the asymmetry in segregation of key…

种群与进化 · 定量生物学 2021-08-11 Jiseon Min , Ariel Amir

Electron transmission through chiral molecules induced by circularly polarized light can be very different for mirror-image structures, a peculiar fact given that the electronic energy spectra of the systems are identical. We propose that…

化学物理 · 物理学 2009-11-13 Spiros S. Skourtis , David N. Beratan , Ron Naaman , Abraham Nitzan , David H. Waldeck

The muscle contraction, operation of ATP synthase, maintaining the shape of a cell are believed to be secured by motor proteins, which can be modelled using the Brownian ratchet mechanism. We consider the randomly flashing ratchet model of…

经典分析与常微分方程 · 数学 2013-05-09 Dmitry Vorotnikov

Biological machines like molecular motors and enzymes operate in dynamic cycles representable as stochastic flows on networks. Current stochastic dynamics describes such flows on fixed networks. Here, we develop a scalable approach to…

统计力学 · 物理学 2026-03-02 Ying-Jen Yang , Ken A. Dill