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Synaptic connections in neuronal circuits are modulated by pre- and post-synaptic spiking activity. Heuristic models of this process of synaptic plasticity can provide excellent fits to results from in-vitro experiments in which pre- and…

神经元与认知 · 定量生物学 2022-07-14 Federico Devalle , Alex Roxin

Spontaneous cortical population activity exhibits a multitude of oscillatory patterns, which often display synchrony during slow-wave sleep or under certain anesthetics and stay asynchronous during quiet wakefulness. The mechanisms behind…

神经元与认知 · 定量生物学 2018-06-20 Rodrigo F. O. Pena , Michael A. Zaks , Antonio C. Roque

Neural oscillations are universal phenomena and can be observed at different levels of neural systems, from single neuron to macroscopic brain. The frequency of those oscillations are related to the brain functions. However, little is know…

神经元与认知 · 定量生物学 2015-07-30 Lianchun Yu , Longfei Wang , Fei Jia , Duojie Jia

We study a stochastic process describing the continuous time evolution of the membrane potentials of finite system of neurons in the absence of external stimuli. The values of the membrane potentials evolve under the effect of {\it chemical…

概率论 · 数学 2017-07-14 Aline Duarte , Guilherme Ost

Complex coherent dynamics is present in a wide variety of neural systems. A typical example is the voltage transitions between up and down states observed in cortical areas in the brain. In this work, we study this phenomenon via a…

神经元与认知 · 定量生物学 2015-05-19 Jorge F. Mejias , Hilbert J. Kappen , Joaquin J. Torres

Synaptic integration is a prominent aspect of neuronal information processing. The detailed mechanisms that modulate synaptic inputs determine the computational properties of any given neuron. We study a simple model for the summation of…

神经元与认知 · 定量生物学 2021-07-15 Adrian Joseph Alva , Harjinder Singh

We propose a stochastic dynamical model of noisy neural networks with complex architectures and discuss activation of neural networks by a stimulus, pacemakers and spontaneous activity. This model has a complex phase diagram with…

无序系统与神经网络 · 物理学 2015-05-13 A. V. Goltsev , F. V. de Abreu , S. N. Dorogovtsev , J. F. F. Mendes

The response of a neural cell to an external stimulus can follow one of the two patterns: Nonresonant neurons monotonously relax to the resting state after excitation while resonant ones show subthreshold oscillations. We investigate how do…

神经元与认知 · 定量生物学 2009-11-10 T. Verechtchaguina , L. Schimansky-Geier , I. M. Sokolov

The theory of Balanced Neural Networks is a very popular explanation for the high degree of variability and stochasticity in the brain's activity. Roughly speaking, it entails that typical neurons receive many excitatory and inhibitory…

概率论 · 数学 2025-05-27 James MacLaurin , Pedro Vilanova

Learning is based on synaptic plasticity, which affects and is driven by neural activity. Because pre- and postsynaptic spiking activity is shaped by randomness, the synaptic weights follow a stochastic process, requiring a probabilistic…

神经元与认知 · 定量生物学 2026-01-14 Jakob Stubenrauch , Naomi Auer , Richard Kempter , Benjamin Lindner

Noise is an inherent part of neuronal dynamics, and thus of the brain. It can be observed in neuronal activity at different spatiotemporal scales, including in neuronal membrane potentials, local field potentials, electroencephalography,…

神经元与认知 · 定量生物学 2019-01-03 Daqing Guo , Matjaz Perc , Tiejun Liu , Dezhong Yao

Using a stochastic generalization of the Hodgkin–Huxley model, we consider the influence of intrinsic channel noise on the synchronization between the spiking activity of the excitable membrane and an externally applied periodic…

生物物理 · 物理学 2007-05-23 Gerhard Schmid , Igor Goychuk , Peter Hanggi

Neurons in the central nervous system are affected by complex and noisy signals due to fluctuations in their cellular environment and in the inputs they receive from many other cells 1,2. Such noise usually increases the probability that a…

神经元与认知 · 定量生物学 2008-05-06 Boris S. Gutkin , Juergen Jost , Henry C. Tuckwell

Neural dynamics is determined by the transmission of discrete synaptic pulses (synaptic shot-noise) among neurons. However, the neural responses are usually obtained within the diffusion approximation modeling synaptic inputs as continuous…

无序系统与神经网络 · 物理学 2025-10-17 Denis S. Goldobin , Maria V. Ageeva , Matteo di Volo , Ferdinand Tixidre , Alessandro Torcini

Self-sustained subthreshold oscillations in a discrete-time model of neuronal behavior are considered. We discuss bifurcation scenarios explaining the birth of these oscillations and their transformation into tonic spikes. Specific features…

细胞行为 · 定量生物学 2009-11-10 Andrey L. Shilnikov , Nikolai F. Rulkov

This paper deals with the problem of inferring the signals and parameters that cause neural activity to occur. The ultimate challenge being to unveil brain's connectivity, here we focus on a microscopic vision of the problem, where single…

统计计算 · 统计学 2015-11-13 Pau Closas , Antoni Guillamon

Neuronal oscillations are closely related to the symptoms of Parkinson's disease (PD). In this study, we explore how random fluctuations (or "stochastic inputs") affect these oscillations in brain states, which reflect the collective…

神经元与认知 · 定量生物学 2025-02-24 Thoa Thieu , Roderick Melnik

Brain rhythms contribute to every aspect of brain function. Here, we study critical and resonance phenomena that precede the emergence of brain rhythms. Using an analytical approach and simulations of a cortical circuit model of neural…

无序系统与神经网络 · 物理学 2015-06-12 A. V. Goltsev , M. A. Lopes , K. -E. Lee , J. F. F. Mendes

Intrinsic stochasticity can induce highly non-trivial effects on dynamical systems, including stochastic and coherence resonance, noise induced bistability, noise-induced oscillations, to name but a few. In this paper we revisit a mechanism…

无序系统与神经网络 · 物理学 2018-07-17 Serena di Santo , Pablo Villegas , Raffaella Burioni , Miguel A. Muñoz

We continue the work of a series of previous studies of a mathematical model that describes the mean-field limit behavior of a homogeneous network of excitatory point spiking neurons. Contrary to other models, here noise is intrinsic to the…

神经元与认知 · 定量生物学 2017-07-20 Guillem Via