相关论文: Longest Life in the Best of Health

The existence of an upper limit to the human lifespan has been widely debated, with studies offering both supporting and opposing evidence. Using unique individual-level death and population records for individuals aged 90 and older in…

A fundamental issue discussed in evolutionary biology is the transition from unicellular to multicellular organisms. Here we develop non-robust models provided in [1] and attempt to get robust models investigated how differentiation of…

We examine the dynamics of an age-structured population model in which the life expectancy of an offspring may be mutated with respect to that of the parent. While the total population of the system always reaches a steady state, the…

Given a sufficiently large universe, numerous civilizations almost surely exist. Some of these civilizations will be short-lived and die out relatively early in their development, i.e., before having the chance to spread to other planets.…

We study the fate of a forager who searches for food performing a random walk on lattices. The forager consumes the available food on the site it visits and leaves it depleted but can survive up to $S$ steps without food. We introduce the…

Author's early work on aging is developed to yield a relationship between life spans and the velocity of aging. The mathematical analysis shows that the mean extent of the advancement of aging throughout one's life is conserved, or…

The "obesity paradox" has been reported in several observational studies, where obesity was shown to be associated to a decreased mortality in individuals suffering from a chronic disease, such as diabetes or heart failure. Causal arguments…

The evolutionary biology of aging is fundamental to understanding the mechanisms of aging and how to develop anti-aging treatments. Thus far most evolutionary theory concerns the genetics of aging with limited physiological integration.…

Aggregated health data such as claims data from health insurances become more and more available for research purposes. Estimates of excess mortality from prevalence and incidence of a chronic condition have only been possible for ages 50…

We study the starvation of a lattice random walker in which each site initially contains one food unit and the walker can travel $\mathcal{S}$ steps without food before starving. When the walker encounters food, the food is completely…

We investigate the dynamics of a greedy forager that moves by random walking in an environment where each site initially contains one unit of food. Upon encountering a food-containing site, the forager eats all the food there and can…

Living systems continuously transform matter and energy through the chemical processes that constitute their metabolism. The overall metabolic rate of an organism correlates positively with its body mass, however both the exact scaling…

Most people around the world still lack access to sufficient quantities of all food groups needed for an active and healthy life. This study traces historical and projected changes in global food systems toward alignment with the new…

Globally, the water crisis has become a significant problem that affects developing and industrialized nations. Water shortage can harm public health by increasing the chance of contracting water-borne diseases, dehydration, and…

Humans experience small fluctuations in their gait when walking on uneven terrain. The fluctuations deviate from the steady, energy-minimizing pattern for level walking, and have no obvious organization. But humans often look ahead when…

We study optimal consumption and retirement using a Cobb-Douglas utility and a simple model in which an interesting bifurcation arises. With high wealth, individuals plan to retire. With low wealth they plan to never retire. At a critical…

Earth-like planets are expected to provide the greatest opportunity for the detection of life beyond the Solar System. However our planet cannot be considered a fair sample, especially if intelligent life exists elsewhere. Just as a…

Recent progresses in data-driven analysis methods, including network-based approaches, are revolutionizing many classical disciplines. These techniques can also be applied to food and nutrition, which must be studied to design healthy…

Motivated by recent research of aging in E. coli, we explore the effects of aging on bacterial fitness. The disposable soma theory of aging was developed to explain how differences in lifespans and aging rates could be linked to life…

Working becomes harder as we grow tired or bored. I model individuals who underestimate these changes in marginal disutility -- as implied by "projection bias" -- when deciding whether or not to continue working. This bias causes people's…