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The forest of mutations associated to a multitype branching forest is obtained by merging together all vertices of its clusters and by preserving connections between them. We first show that the forest of mutations of any mulitype branching…

概率论 · 数学 2015-10-06 Loïc Chaumont , Thi Ngoc Anh Nguyen

In biological systems, expression dynamics that can provide fitted phenotype patterns with respect to a specific function have evolved through mutations. This has been observed in the evolution of proteins for realizing folding dynamics…

无序系统与神经网络 · 物理学 2015-05-13 Ayaka Sakata , Koji Hukushima , Kunihiko Kaneko

We consider an aggregation model for two interacting species. The coupling between the species is via their velocities, that incorporate self- and cross-interactions. Our main interest is categorizing the possible steady states of the…

偏微分方程分析 · 数学 2016-12-26 Joep H. M. Evers , Razvan C. Fetecau , Theodore Kolokolnikov

A prediction interval covers a future observation from a random process in repeated sampling, and is typically constructed by identifying a pivotal quantity that is also an ancillary statistic. Analogously, a tolerance interval covers a…

统计方法学 · 统计学 2022-01-19 Geoffrey S Johnson

Identifying and quantifying the benefits of sex and recombination is a long standing problem in evolutionary theory. In particular, contradictory claims have been made about the existence of a benefit of recombination on high dimensional…

种群与进化 · 定量生物学 2014-11-11 Stefan Nowak , Johannes Neidhart , Ivan G. Szendro , Joachim Krug

Mechanisms leading to speciation are a major focus in evolutionary biology. In this paper, we present and study a stochastic model of population where individuals, with type a or A, are equivalent from ecological, demographical and spatial…

种群与进化 · 定量生物学 2017-04-20 Camille Coron , Manon Costa , Hélène Leman , Charline Smadi

Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

种群与进化 · 定量生物学 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

Multilevel or hierarchical data structures can occur in many areas of research, including economics, psychology, sociology, agriculture, medicine, and public health. Over the last 25 years, there has been increasing interest in developing…

统计方法学 · 统计学 2018-01-08 Bernet S. Kato , Carel F. W. Peeters

We review models of biological evolution in which the population frequency changes deterministically with time. If the population is self-replicating, although the equations for simple prototypes can be linearised, nonlinear equations arise…

种群与进化 · 定量生物学 2015-05-27 Kavita Jain , Sarada Seetharaman

The Schelling model of segregation looks to explain the way in which a population of agents or particles of two types may come to organise itself into large homogeneous clusters, and can be seen as a variant of the Ising model in which the…

离散数学 · 计算机科学 2015-08-13 George Barmpalias , Richard Elwes , Andy Lewis-Pye

A microscopic model is developed, within the frame of the theory of quantitative traits, to study both numerically and analytically the combined effect of competition and assortativity on the sympatric speciation process, i.e. speciation in…

种群与进化 · 定量生物学 2007-05-23 Franco Bagnoli , Carlo Guardiani

Randomly coupled Ising spins constitute the classical model of collective phenomena in disordered systems, with applications covering ferromagnetism, combinatorial optimization, protein folding, stock market dynamics, and social dynamics.…

无序系统与神经网络 · 物理学 2016-08-24 David Dahmen , Hannah Bos , Moritz Helias

The presence of phenomena analogous to phase transition in Statistical Mechanics, has been suggested in the evolution of a polygenic trait under stabilizing selection, mutation and genetic drift. By using numerical simulations of a model…

种群与进化 · 定量生物学 2017-02-13 Annalisa Fierro , Sergio Cocozza , Antonella Monticelli , Giovanni Scala , Gennaro Miele

We are interested in modeling some two-level population dynamics, resulting from the interplay of ecological interactions and phenotypic variation of individuals (or hosts) and the evolution of cells (or parasites) of two types living in…

概率论 · 数学 2011-01-21 Sylvie Méléard , Sylvie Roelly

Some recent works reveal that there are models of differential equations for the mean and variance of infected individuals that reproduce the SIS epidemic model at some point. This stochastic SIS epidemic model can be interpreted as a…

种群与进化 · 定量生物学 2020-08-07 Oğul Esen , Eduardo Fernández-Saiz , Cristina Sardón , Marcin Zając

A parameter-dependent model involving nonlinear diffusion for an age-structured population is studied. The parameter measures the intensity of the mortality. A bifurcation approach is used to establish existence of positive equilibrium…

偏微分方程分析 · 数学 2010-02-10 Christoph Walker

Phenotypic variation is a hallmark of cellular physiology. Metabolic heterogeneity, in particular, underpins single-cell phenomena such as microbial drug tolerance and growth variability. Much research has focussed on transcriptomic and…

分子网络 · 定量生物学 2019-01-31 Mona K. Tonn , Philipp Thomas , Mauricio Barahona , Diego A Oyarzún

Spectral statistics of systems that undergo many--body localization transition are studied. An analysis of the gap ratio statistics from the perspective of inter- and intra-sample randomness allows us to pin point differences between…

无序系统与神经网络 · 物理学 2019-03-06 Piotr Sierant , Jakub Zakrzewski

We analyze a nonlocal PDE model describing the dynamics of adaptation of a phenotypically structured population, under the effects of mutation and selection, in a changing environment. Previous studies have analyzed the large-time behavior…

偏微分方程分析 · 数学 2020-09-25 Lionel Roques , Florian Patout , Olivier Bonnefon , Guillaume Martin

Exploiting the mathematical curiosity of intransitive dice, we present a simple theoretical model for co-evolution that captures scales ranging from the genome of the individual to the system-wide emergence of species diversity. We study a…

种群与进化 · 定量生物学 2022-12-02 Julius B. Kirkegaard , Kim Sneppen