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相关论文: Formalizing the gene centered view of evolution

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Embryonic development leads to the reproducible and ordered appearance of complexity from egg to adult. The successive differentiation of different cell types, that elaborates this complexity, result from the activity of gene networks and…

定量方法 · 定量生物学 2022-05-11 David A. Rand , Archishman Raju , Meritxell Saez , Francis Corson , Eric D. Siggia

While Neutral Theory famously describes the number of discrete genetic differences in populations, we consider the number of genetic backgrounds under which such differences are observed - setting limits to the generalizability of their…

种群与进化 · 定量生物学 2023-03-21 Andre F. Ribeiro

Evolutionary forms, as well as exterior forms, are skew-symmetric differential forms. But in contrast to the exterior forms, the basis of evolutionary forms is deforming manifolds (with unclosed metric forms). Such forms possess a…

微分几何 · 数学 2007-05-23 L. I. Petrova

At any moment in time, evolution is faced with a formidable challenge: refining the already highly optimised design of biological species, a feat accomplished through all preceding generations. In such a scenario, the impact of random…

种群与进化 · 定量生物学 2024-02-20 Alessandro Fontana , Marios Kyriazis

A phylogenetic tree is a way to organize a finite set of species, individuals or other sources of related data. The species for which we have existing DNA data make up the set of leaves of the tree. The balanced minimal evolution method of…

组合数学 · 数学 2016-08-05 Stefan Forcey , Logan Keefe , William Sands

The paper discusses a connection between asymmetric reproduction -- that is reproduction in a parent-child relationship where the parent does not mutate during reproduction --, the fact that all non-viral lifeforms bear genes of their…

种群与进化 · 定量生物学 2015-08-11 Norbert Michael Mayer

Any permutation has a disjoint cycle decomposition and concept generates an equivalence class on the symmetry group called the cycle-type. The main focus of this work is on permutations of restricted cycle-types, with particular emphasis on…

组合数学 · 数学 2014-06-11 Tewodros Amdeberhan , Victor H. Moll

Centering theory posits a discourse center, a distinguished discourse entity that is the topic of a discourse. A simplified version of this theory is developed in a Dynamic Semantics framework. In the resulting system, the mechanism of…

cmp-lg · 计算机科学 2007-05-23 Daniel Hardt

The treatment of time in relativity does not conform to that in quantum theory. To resolve the discrepancy, a formalization of time is introduced in an accompanying paper, starting from the assumption that the treatment of time in physics…

量子物理 · 物理学 2024-11-06 Per Östborn

Genetic drift is stochastic fluctuations of alleles frequencies in a population due to sampling effects. We consider a model of drift in an equilibrium population, with high mutation rates: few functional mutations per generation. Such…

种群与进化 · 定量生物学 2017-01-12 Alexey A. Shadrin , Dmitri V. Parkhomchuk

In the theoretical biology framework one fundamental problem is the so-called error catastrophe in Darwinian evolution models. We reexamine Eigen's fundamental equations by mapping them into a polymer depinning transition problem in a…

凝聚态物理 · 物理学 2009-10-28 S. Galluccio , R. Graber , Y. -C. Zhang

A central goal of evolutionary biology is to explain the origins and distribution of diversity across life. Beyond species or genetic diversity, we also observe diversity in the circuits (genetic or otherwise) underlying complex functional…

种群与进化 · 定量生物学 2018-06-06 Ali Tehrani-Saleh , Thomas LaBar , Christoph Adami

Phylogenetic diversity is a measure for describing how much of an evolutionary tree is spanned by a subset of species. If one applies this to the (unknown) subset of current species that will still be present at some future time, then this…

亚细胞过程 · 定量生物学 2009-09-29 Beata Faller , Fabio Pardi , Mike Steel

A variational lattice model is proposed to define an evolution of sets from a single point (nucleation) following a criterion of "maximization" of the perimeter. At a discrete level, the evolution has a "checkerboard" structure and its…

偏微分方程分析 · 数学 2021-10-27 Andrea Braides , Giovanni Scilla , Antonio Tribuzio

A simple model of species origin resulted from dynamic features of a population, solely, is developed. The model is based on the evolution optimality in space distribution, and the selection is gone over the mobility. Some biological issues…

种群与进化 · 定量生物学 2008-04-25 Michael G. Sadovsky

We discuss how to use a Genetic Regulatory Network as an evolutionary representation to solve a typical GP reinforcement problem, the pole balancing. The network is a modified version of an Artificial Regulatory Network proposed a few years…

人工智能 · 计算机科学 2010-05-20 Miguel Nicolau , Marc Schoenauer , W. Banzhaf

We study a universal object for the genealogy of a sample in populations with mutations: the critical birth-death process with Poissonian mutations, conditioned on its population size at a fixed time horizon. We show how this process arises…

概率论 · 数学 2014-07-30 G. Achaz , C. Delaporte , A. Lambert

We apply the theory of learning to physically renormalizable systems in an attempt to develop a theory of biological evolution, including the origin of life, as multilevel learning. We formulate seven fundamental principles of evolution…

种群与进化 · 定量生物学 2022-10-12 Vitaly Vanchurin , Yuri I. Wolf , Mikhail I. Katsnelson , Eugene V. Koonin

Any process in which competing solutions replicate with errors and numbers of their copies depend on their respective fitnesses is the evolutionary optimization process. As during carcinogenesis mutated genomes replicate according to their…

种群与进化 · 定量生物学 2009-12-15 B. Brutovsky , D. Horvath

Phylogenetics is the study of the evolutionary relationships between organisms. One of the main challenges in the field is to take biological data for a group of organisms and to infer an evolutionary tree, a graph that represents these…

种群与进化 · 定量生物学 2019-06-05 Elizabeth Gross , Colby Long , Joseph Rusinko