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In this article, we propose a generalized weighted version of the well-known Benjamini-Hochberg (BH) procedure. The rigorous weighting scheme used by our method enables it to encode structural information from simultaneous multi-way…

统计方法学 · 统计学 2021-05-25 Shinjini Nandi , Sanat K. Sarkar

Controlling the false discovery rate (FDR) in variable selection becomes challenging when predictors are correlated, as existing methods often exclude all members of correlated groups and consequently perform poorly for prediction. We…

统计方法学 · 统计学 2026-03-03 Sarah Organ , Toby Kenney , Hong Gu

In multiple testing problems, where a large number of hypotheses are tested simultaneously, false discovery rate (FDR) control can be achieved with the well-known Benjamini-Hochberg procedure, which adapts to the amount of signal present in…

统计方法学 · 统计学 2017-09-14 Ang Li , Rina Foygel Barber

We propose a novel multiple testing methodology for controlling the false discovery rate (FDR) in high-dimensional linear models that integrates model-X knockoff techniques with debiased penalized regression estimators. At the foundation of…

统计方法学 · 统计学 2026-03-17 Jinyuan Chang , Chenlong Li , Cheng Yong Tang , Zhengtian Zhu

In multiple hypothesis testing, it is well known that adaptive procedures can enhance power via incorporating information about the number of true nulls present. Under independence, we establish that two adaptive false discovery rate (FDR)…

统计方法学 · 统计学 2024-01-25 Dennis Leung , Ninh Tran

In large-scale multiple hypothesis testing problems, the false discovery exceedance (FDX) provides a desirable alternative to the widely used false discovery rate (FDR) when the false discovery proportion (FDP) is highly variable. We…

统计方法学 · 统计学 2023-04-21 Pallavi Basu , Luella Fu , Alessio Saretto , Wenguang Sun

False discovery rate (FDR) control is a popular approach for maintaining the integrity of statistical analyses, especially in high-dimensional data settings, where multiple comparisons increase the risk of false positives. FDR control has…

信号处理 · 电气工程与系统科学 2026-03-03 Fabian Scheidt , Jasin Machkour , Michael Muma

In online multiple testing, an a priori unknown number of hypotheses are tested sequentially, i.e. at each time point a test decision for the current hypothesis has to be made using only the data available so far. Although many powerful…

统计方法学 · 统计学 2025-03-11 Vincent Jankovic , Lasse Fischer , Werner Brannath

When testing multiple hypothesis in a survey --e.g. many different source locations, template waveforms, and so on-- the final result consists in a set of confidence intervals, each one at a desired confidence level. But the probability…

广义相对论与量子宇宙学 · 物理学 2009-11-11 L. Baggio , G. A. Prodi

In many scientific applications, hypotheses are generated and tested continuously in a stream. We develop a framework for improving online multiple testing procedures with false discovery rate (FDR) control under arbitrary dependence. Our…

统计方法学 · 统计学 2026-03-27 Ziyu Xu , Lasse Fischer , Aaditya Ramdas

This paper develops a general framework for controlling the false discovery rate (FDR) in multiple testing of Gaussian means against two-sided alternatives. The widely used Benjamini-Hochberg (BH) procedure provides exact FDR control under…

统计方法学 · 统计学 2025-11-26 Deepra Ghosh , Sanat K. Sarkar

Modern biological studies often involve testing many hypotheses organized in a group or a hierarchical structure, such as a directed acyclic graph (DAG). In these studies, researchers often wish to control the false discovery rate (FDR)…

统计方法学 · 统计学 2025-09-22 Marina Bogomolov , Shinjini Nandi

Diagnostic accuracy studies assess sensitivity and specificity of a new index test in relation to an established comparator or the reference standard. The development and selection of the index test is usually assumed to be conducted prior…

统计方法学 · 统计学 2022-08-30 Max Westphal , Antonia Zapf

In contemporary research, data scientists often test an infinite sequence of hypotheses $H_1,H_2,\ldots$ one by one, and are required to make real-time decisions without knowing the future hypotheses or data. In this paper, we consider such…

统计方法学 · 统计学 2025-12-16 Lasse Fischer , Aaditya Ramdas

In multiple testing several criteria to control for type I errors exist. The false discovery rate, which evaluates the expected proportion of false discoveries among the rejected null hypotheses, has become the standard approach in this…

统计方法学 · 统计学 2023-11-03 Jacobo de Uña-Álvarez

The positive false discovery rate (pFDR) is a useful overall measure of errors for multiple hypothesis testing, especially when the underlying goal is to attain one or more discoveries. Control of pFDR critically depends on how much…

统计理论 · 数学 2011-11-09 Zhiyi Chi

A statistical test can be seen as a procedure to produce a decision based on observed data, where some decisions consist of rejecting a hypothesis (yielding a significant result) and some do not, and where one controls the probability to…

统计理论 · 数学 2017-10-19 Aaron McDaid , Zoltan Kutalik , Valentin Rousson

We introduce a multiple testing procedure (TreeBH) which addresses the challenge of controlling error rates at multiple levels of resolution. Conceptually, we frame this problem as the selection of hypotheses which are organized…

统计方法学 · 统计学 2018-10-25 Marina Bogomolov , Christine B. Peterson , Yoav Benjamini , Chiara Sabatti

This is a chapter of the forthcoming Handbook of Multiple Testing. We consider a variety of model selection strategies in a high-dimensional setting, where the number of potential predictors p is large compared to the number of available…

统计方法学 · 统计学 2020-11-25 Malgorzata Bogdan , Florian Frommlet

Multiple hypothesis testing problems arise naturally in science. In this paper, we introduce the new Fast Closed Testing (FACT) method for multiple testing, controlling the family-wise error rate. This error rate is state of the art in many…

统计方法学 · 统计学 2020-01-22 Edgar Dobriban