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This thesis responds to the challenges of using a large number, such as thousands, of features in regression and classification problems. There are two situations where such high dimensional features arise. One is when high dimensional…

机器学习 · 统计学 2007-09-20 Longhai Li

Bayesian optimization works effectively optimizing parameters in black-box problems. However, this method did not work for high-dimensional parameters in limited trials. Parameters can be efficiently explored by nonlinearly embedding them…

机器学习 · 计算机科学 2022-06-14 Shoki Miyagawa , Atsuyoshi Yano , Naoko Sawada , Isamu Ogawa

Geometric matching is a key step in computer vision tasks. Previous learning-based methods for geometric matching concentrate more on improving alignment quality, while we argue the importance of naturalness issue simultaneously. To deal…

计算机视觉与模式识别 · 计算机科学 2018-07-16 Yifang Xu , Tianli Liao , Jing Chen

Bayesian learning with Gaussian processes demonstrates encouraging regression and classification performances in solving computer vision tasks. However, Bayesian methods on 3D manifold-valued vision data, such as meshes and point clouds,…

计算机视觉与模式识别 · 计算机科学 2021-11-02 Yonghui Fan , Yalin Wang

Protein design is the inverse approach of the three-dimensional (3D) structure prediction for elucidating the relationship between the 3D structures and amino acid sequences. In general, the computation of the protein design involves a…

生物物理 · 物理学 2021-07-14 Tomoei Takahashi , George Chikenji , Kei Tokita

Many analyses require linking records from two databases comprising overlapping sets of individuals. In the absence of unique identifiers, the linkage procedure often involves matching on a set of categorical variables, such as…

应用统计 · 统计学 2017-06-12 Nicole M. Dalzell , Jerome P. Reiter

Shape matching has been a long-studied problem for the computer graphics and vision community. The objective is to predict a dense correspondence between meshes that have a certain degree of deformation. Existing methods either consider the…

计算机视觉与模式识别 · 计算机科学 2022-02-04 Mahdi Saleh , Shun-Cheng Wu , Luca Cosmo , Nassir Navab , Benjamin Busam , Federico Tombari

Removing geometrical details from a complex domain is a classical operation in computer aided design. This procedure simplifies the meshing process, and it enables faster simulations with less memory requirements. However, depending on the…

数值分析 · 数学 2024-07-18 Annalisa Buffa , Ondine Chanon , Rafael Vázquez

Understanding sub-cellular protein localisation is an essential component to analyse context specific protein function. Recent advances in quantitative mass-spectrometry (MS) have led to high resolution mapping of thousands of proteins to…

应用统计 · 统计学 2019-03-12 Oliver M. Crook , Kathryn S. Lilley , Laurent Gatto , Paul D. W. Kirk

Inverse protein folding -- the task of predicting a protein sequence from its backbone atom coordinates -- has surfaced as an important problem in the "top down", de novo design of proteins. Contemporary approaches have cast this problem as…

Unlabeled shape analysis is a rapidly emerging and challenging area of statistics. This has been driven by various novel applications in bioinformatics. We consider here the situation where two configurations are matched under various…

应用统计 · 统计学 2012-09-28 Kanti V. Mardia , Emma M. Petty , Charles C. Taylor

The performance of many machine learning models depends on their hyper-parameter settings. Bayesian Optimization has become a successful tool for hyper-parameter optimization of machine learning algorithms, which aims to identify optimal…

机器学习 · 计算机科学 2020-08-04 Lidan Wang , Franck Dernoncourt , Trung Bui

Fitting models to data using Bayesian inference is quite common, but when each point in parameter space gives a curve, fitting the curve to a data set requires new nuisance parameters, which specify the metric embedding the one-dimensional…

数据分析、统计与概率 · 物理学 2018-02-23 Andrew W. Steiner

Calibration or parameter identification is used with computational mechanics models related to observed data of the modeled process to find model parameters such that good similarity between model prediction and observation is achieved. We…

计算工程、金融与科学 · 计算机科学 2022-12-26 Harald Willmann , Jonas Nitzler , Sebastian Brandstaeter , Wolfgang A. Wall

Bayesian calibration of computer models tunes unknown input parameters by comparing outputs with observations. For model outputs that are distributed over space, this becomes computationally expensive because of the output size. To overcome…

统计方法学 · 统计学 2018-10-05 Kai-Lan Chang , Serge Guillas

In statistical applications, it is common to encounter parameters supported on a varying or unknown dimensional space. Examples include the fused lasso regression, the matrix recovery under an unknown low rank, etc. Despite the ease of…

统计方法学 · 统计学 2022-10-04 Maoran Xu , Hua Zhou , Yujie Hu , Leo L. Duan

We propose the first Bayesian methods for detecting change points in high-dimensional mean and covariance structures. These methods are constructed using pairwise Bayes factors, leveraging modularization to identify significant changes in…

统计方法学 · 统计学 2024-11-25 Jaehoon Kim , Kyoungjae Lee , Lizhen Lin

Introduction : Mass spectrometry approaches are very attractive to detect protein panels in a sensitive and high speed way. MS can be coupled to many proteomic separation techniques. However, controlling technological variability on these…

基因组学 · 定量生物学 2012-02-23 Pierre Grangeat , Pascal Szacherski , Laurent Gerfault , Jean-François Giovannelli

Many real-world problems can be formulated as the alignment between two geometric patterns. Previously, a great amount of research focus on the alignment of 2D or 3D patterns in the field of computer vision. Recently, the alignment problem…

计算机视觉与模式识别 · 计算机科学 2023-07-11 Hu Ding , Wenjie Liu , Mingquan Ye

Machine learning holds tremendous promise for transforming the fundamental practice of scientific discovery by virtue of its data-driven nature. With the ever-increasing stream of research data collection, it would be appealing to…

机器学习 · 计算机科学 2024-03-06 Jianan Fan , Dongnan Liu , Hang Chang , Heng Huang , Mei Chen , Weidong Cai