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The classical macroscopic chemotaxis equations have previously been derived from an individual-based description of the tactic response of cells that use a "run-and-tumble" strategy in response to environmental cues. Here we derive…

细胞行为 · 定量生物学 2007-05-23 Radek Erban , Hans G. Othmer

Biological systems like ciliated microorganisms are capable to respond to the external chemical gradients, a process known as chemotaxis which has been studied here using the chiral squirmer model. This theoretical model considers the…

生物物理 · 物理学 2018-04-18 Ruma Maity , P. S. Burada

Chemotaxis refers to the directed movement of cells in response to a chemical signal called chemoattractant. A crucial point in the mathematical modeling of chemotactic processes is the correct description of the chemotactic sensitivity and…

偏微分方程分析 · 数学 2015-01-08 Herbert Egger , Jan-Frederik Pietschmann , Matthias Schlottbom

In chemotaxis, cells are modulating their migration patterns in response to concentration gradients of a guiding substance. Immune cells are believed to use such chemotactic sensing for remotely detecting and homing in on pathogens.…

细胞行为 · 定量生物学 2019-02-28 Claus Metzner

In this article we highlight chemotaxis (cellular movement) as a rich source of potential engineering applications and computational models, highlighting current research and possible future work. We first give a brief description of the…

细胞行为 · 定量生物学 2007-05-23 Martyn Amos , David A. Hodgson , Alan Gibbons

We study single cell E.coli chemotaxis in a spatio-temporally varying attractant environment. Modeling the attractant concentration in the form of a traveling sine wave, we measure in our simulations, the chemotactic drift velocity of the…

细胞行为 · 定量生物学 2025-06-06 Shobhan Dev Mandal , Sakuntala Chatterjee

Many phenomena in biology involve both reactions and chemotaxis. These processes can clearly influence each other, and chemotaxis can play an important role in sustaining and speeding up the reaction. In continuation of our earlier work, we…

偏微分方程分析 · 数学 2015-06-04 Alexander Kiselev , Lenya Ryzhik

Chemotaxis and reactions are fundamental processes in biology, often intricately intertwined. Chemotaxis, in particular, can be crucial in maintaining and accelerating a reaction. In this work, we extend the investigation initiated by…

偏微分方程分析 · 数学 2024-12-31 Crystianne L. De Andrade , Alexander A. Kiselev

Bacteria can chemotactically migrate up attractant gradients by controlling run-and-tumble motility patterns. In addition to this well-known chemotactic behaviour, several soil and marine bacterial species perform chemokinesis: they adjust…

A wide array of biological systems can navigate in shallow gradients of chemoattractant with remarkable precision. Whilst previous approaches model such systems using coarse-grained chemical density profiles, we construct a dynamical model…

生物物理 · 物理学 2023-12-19 Jacob Knight , Paula García-Galindo , Johannes Pausch , Gunnar Pruessner

Active particles with their characteristic feature of self-propulsion are regarded as the simplest models for motility in living systems. The accumulation of active particles in low activity regions has led to the general belief that…

软凝聚态物质 · 物理学 2021-05-26 Hidde D. Vuijk , Holger Merlitz , Michael Lang , Abhinav Sharma , Jens-Uwe Sommer

As motivated by studies of cellular motility driven by spatiotemporal chemotactic gradients in microdevices, we develop a framework for constructing approximate analytical solutions for the location, speed and cellular densities for cell…

偏微分方程分析 · 数学 2022-11-09 Jacobo Ayensa-Jiménez , Mohamed H. Doweidar , Manuel Doblaré , Eamonn A. Gaffney

Chemotaxis plays a crucial role in a variety of processes in biology and ecology. Quite often it acts to improve efficiency of biological reactions; one example is the immune system signalling, where infected tissues release chemokines…

偏微分方程分析 · 数学 2025-08-20 Jing An , Alexander Kiselev , Yao Yao

Chemotaxis, the movement of an organism in response to chemical stimuli, is a typical feature of many microbiological systems. In particular, the social amoeba \textit{Disctyostelium discoideum} is widely used as a model organism, but it is…

细胞行为 · 定量生物学 2025-08-04 Daniele Proverbio , Marco Maggiora

Cells encounter a diverse array of physical and chemical signals as they navigate their natural surroundings. However, their response to the simultaneous presence of multiple cues remains elusive. Particularly, the impact of topography…

偏微分方程分析 · 数学 2026-03-10 Valeria Cuentas , Elio Espejo

Bacteria are able to respond to environmental signals by changing their rules of movement. When we take into account chemical signals in the environment, this behaviour is often called chemotaxis. At the individual-level, chemotaxis…

偏微分方程分析 · 数学 2007-05-23 Radek Erban , Hyung Ju Hwang

Chemotaxis describes the movement of an organism, such as single or multi-cellular organisms and bacteria, in response to a chemical stimulus. Two widely used models to describe the phenomenon are the celebrated Keller-Segel equation and a…

偏微分方程分析 · 数学 2024-01-11 Kathrin Hellmuth , Christian Klingenberg , Qin Li , Min Tang

Chemotaxis is typically modeled in the context of cellular motion towards a static, exogenous source of chemoattractant. Here, we propose a time-dependent mechanism of chemotaxis in which a self-propelled particle ({\it e.g.}, a cell)…

细胞行为 · 定量生物学 2026-05-12 Sarah A. Nowak , Buddhapriya Chakrabarti , Tom Chou , Ajay Gopinathan

Chemotaxis is the process by which cells behave in a way that follows the chemical gradient. Applications to bacteria growth, tissue inflammation, and vascular tumors provide a focus on optimization strategies. Experiments can characterize…

最优化与控制 · 数学 2007-07-18 K. Renee Fister , Maeve L. McCarthy

Directed cell motion in response to an external chemical gradient occurs in many biological phenomena such as wound healing, angiogenesis, and cancer metastasis. Chemotaxis is often characterized by the accuracy, persistence, and speed of…

细胞行为 · 定量生物学 2019-06-19 Julien Varennes , Hye-ran Moon , Soutick Saha , Andrew Mugler , Bumsoo Han