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In the drug discovery process, where experiments can be costly and time-consuming, computational models that predict drug-target interactions are valuable tools to accelerate the development of new therapeutic agents. Estimating the…

机器学习 · 计算机科学 2024-07-22 Hannah Rosa Friesacher , Ola Engkvist , Lewis Mervin , Yves Moreau , Adam Arany

This paper investigates a hybrid learning framework for reinforcement learning (RL) in which the agent can leverage both an offline dataset and online interactions to learn the optimal policy. We present a unified algorithm and analysis and…

机器学习 · 计算机科学 2025-07-01 Ruiquan Huang , Donghao Li , Chengshuai Shi , Cong Shen , Jing Yang

Conformal prediction is a framework that provides valid uncertainty quantification for general models with exchangeable data. However, in the online learning and time-series settings, exchangeability is not satisfied. Existing online…

机器学习 · 计算机科学 2026-05-11 Yuheng Lai , Garvesh Raskutti

The majority of high energy physics experiments rely on data acquisition and hardware-based trigger systems performing a number of stringent selections before storing data for offline analysis. The online reconstruction and selection…

仪器与探测器 · 物理学 2022-06-15 Matteo Migliorini , Jacopo Pazzini , Andrea Triossi , Marco Zanetti , Alberto Zucchetta

Standard methods in computer model calibration treat the calibration parameters as constant throughout the domain of control inputs. In many applications, systematic variation may cause the best values for the calibration parameters to…

统计方法学 · 统计学 2017-02-09 D. Andrew Brown , Sez Atamturktur

For constrained linear systems with bounded disturbances and parametric uncertainty, we propose a robust adaptive model predictive control strategy with online parameter estimation. Constraints enforcing persistently exciting closed loop…

最优化与控制 · 数学 2023-03-08 Xiaonan Lu , Mark Cannon

Extrinsic calibration is essential for multi-sensor fusion, existing methods rely on structured targets or fully-excited data, limiting real-world applicability. Online calibration further suffers from weak excitation, leading to unreliable…

机器人学 · 计算机科学 2025-08-11 Baorun Li , Chengrui Zhu , Siyi Du , Bingran Chen , Jie Ren , Wenfei Wang , Yong Liu , Jiajun Lv

In a sequential regression setting, a decision-maker may be primarily concerned with whether the future observation will increase or decrease compared to the current one, rather than the actual value of the future observation. In this…

机器学习 · 计算机科学 2023-06-09 Youngseog Chung , Aaron Rumack , Chirag Gupta

In reinforcement learning (RL) research, it is common to assume access to direct online interactions with the environment. However in many real-world applications, access to the environment is limited to a fixed offline dataset of logged…

机器学习 · 计算机科学 2019-11-27 Yifan Wu , George Tucker , Ofir Nachum

Pushing is a useful robotic capability for positioning and reorienting objects. The ability to accurately predict the effect of pushes can enable efficient trajectory planning and complicated object manipulation. Physical prediction models…

机器人学 · 计算机科学 2019-10-21 Huidong Gao , Yi Ouyang , Masayoshi Tomizuka

Researchers have identified various sources of tool positioning errors for articulated industrial robots and have proposed dedicated compensation strategies. However, these typically require individual, specialized experiments with separate…

机器人学 · 计算机科学 2026-01-26 Philip Tobuschat , Simon Duenser , Markus Bambach , Ivo Aschwanden

Online and AI-based symptom checkers are applications that assist medical laypeople in diagnosing their symptoms and determining which course of action to take. When evaluating these tools, previous studies primarily used an approach…

人机交互 · 计算机科学 2025-06-30 Marvin Kopka , Markus A. Feufel

This paper presents a distributed simulation based method for harmonic resonance assessment (HRA) in multi-area large-scale power systems. Further consideration is devoted to the early harmonic frequency-scan formulation to shape them into…

信号处理 · 电气工程与系统科学 2018-08-22 Amirreza Sahami , Shahram Montaser Kouhsari

The field of algorithms with predictions incorporates machine learning advice in the design of online algorithms to improve real-world performance. A central consideration is the extent to which predictions can be trusted -- while existing…

机器学习 · 统计学 2026-03-26 Judy Hanwen Shen , Ellen Vitercik , Anders Wikum

This paper presents a novel framework for collective control of Distributed Energy Resources (DERs) in active Distribution Networks (DNs). The proposed approach unifies the commonly employed local (i.e., decentralized) voltage and frequency…

系统与控制 · 电气工程与系统科学 2024-06-19 Ognjen Stanojev , Yi Guo , Gabriela Hug

Since 2022, the LHCb detector has been taking both proton-proton and lead-ion data at the LHC collision rate using a fully software-based trigger. This has been implemented on GPUs at its first stage and CPUs at its second. The setup allows…

高能物理 - 实验 · 物理学 2024-12-09 Andy Morris

Online feedback-based optimization has become a promising framework for real-time optimization and control of complex engineering systems. This tutorial paper surveys the recent advances in the field as well as provides novel convergence…

最优化与控制 · 数学 2023-09-07 Andrey Bernstein , Joshua Comden , Yue Chen , Jing Wang

Ordinary differential equation models are nowadays widely used for the mechanistic description of biological processes and their temporal evolution. These models typically have many unknown and non-measurable parameters, which have to be…

定量方法 · 定量生物学 2021-05-27 Alejandro F. Villaverde , Dilan Pathirana , Fabian Fröhlich , Jan Hasenauer , Julio R. Banga

Accurate calibration of sensor extrinsic parameters for ground robotic systems (i.e., relative poses) is crucial for ensuring spatial alignment and achieving high-performance perception. However, existing calibration methods typically…

机器人学 · 计算机科学 2025-06-17 Jiang Wang , Yaozhong Kang , Linya Fu , Kazuhiro Nakadai , He Kong

The web is complex, open-ended, and constantly changing, making it challenging to scale training data for visual web agents. Existing data collection attempts remain limited to offline trajectories for supervised fine-tuning or a handful of…