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相关论文: DNA double helices for single molecule electronics

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Based on modern single molecule techniques, we devise a number of possible experimental setups to probe local properties of DNA such as the presence of DNA-knots, loops or folds, or to obtain information on the DNA-sequence. Similarly, DNA…

软凝聚态物质 · 物理学 2007-05-23 Ralf Metzler , Tobias Ambjoernsson

Synthetic molecular motors are an appealing means to control motion at the nanoscale, but understanding their behaviour as single-molecule actuators and integrating them into larger, functional systems remain technical challenges.…

We report on our theoretical investigations of the electronic states in a DNA molecule. We have used a two-leg charge ladder model where electron-electron interactions and the electron spin have been taken into account. The energy spectra…

无序系统与神经网络 · 物理学 2009-11-10 V. M. Apalkov , Tapash Chakraborty

The computational modelling of DNA is becoming crucial in light of new advances in DNA nanotechnology, single-molecule experiments and in vivo DNA tampering. Here we present a mesoscopic model for double stranded DNA (dsDNA) at the single…

软凝聚态物质 · 物理学 2025-02-03 Y. A. G. Fosado , D. Michieletto , J. Allan , C. Brackley , O. Henrich , D. Marenduzzo

Measurements of electron transfer rates as well as of charge transport characteristics in DNA produced a number of seemingly contradictory results, ranging from insulating behaviour to the suggestion that DNA is an efficient medium for…

软凝聚态物质 · 物理学 2007-05-23 R. Bulla , R. Gutierrez , G. Cuniberti

Within a simple elastic theory, we study the elongation versus force characteristics of a supercoiled DNA molecule at thermal equilibrium in the regime of small supercoiling. The partition function is mapped to the path integral…

软凝聚态物质 · 物理学 2016-08-31 C. Bouchiat , M. Mezard

It is a standard exercise in mechanical engineering to infer the external forces and torques on a body from its static shape and known elastic properties. Here we apply this kind of analysis to distorted double-helical DNA in complexes with…

生物大分子 · 定量生物学 2009-11-13 Nils B. Becker , Ralf Everaers

A solid-state nanopore can electrophoretically capture a DNA molecule and pull it through in a folded configuration. The resulting ionic current signal indicates where along its length the DNA was captured. A statistical study using an 8 nm…

生物物理 · 物理学 2015-06-11 Mirna Mihovilovic , Nick Hagerty , Derek Stein

In recent years significant attention has been attracted to proposals which utilize DNA for nanotechnological applications. Potential applications of these ideas range from the programmable self-assembly of colloidal crystals, to biosensors…

软凝聚态物质 · 物理学 2008-05-02 Nicholas A. Licata

In many organisms, homologous (or repetitive) chromosomal regions can associate or/and undergo concerted epigenetic changes in the absence of DNA breakage and recombination. The direct specific pairing of DNA duplexes with similar…

生物大分子 · 定量生物学 2022-10-26 Alexey K. Mazur , Eugene Gladyshev

Due to its polyionic character the DNA double helix is stable and biologically active only in salty aqueous media where its charge is compensated by solvent counterions. Monovalent metal ions are ubiquitous in DNA environment and they are…

生物物理 · 物理学 2007-05-23 Alexey K. Mazur

From a nanoscience perspective, cellular processes and their reduced in vitro imitations provide extraordinary examples for highly robust few or single molecule reaction pathways. A prime example are biochemical reactions involving DNA…

生物物理 · 物理学 2007-05-23 Ralf Metzler , Tobias Ambjoernsson , Andreas Hanke , Yongli Zhang , Stephen Levene

Motivated by the wide ranging experimental results on the conductivity of DNA, we have investigated extraordinary configurations and chemical environments in which DNA might become a true molecular wire, perticularly from enhanced…

软凝聚态物质 · 物理学 2009-09-29 R. G. Endres , D. L. Cox , R. R. P. Singh

We propose a DNA sequencing scheme based on silicene nanopores. Using first principles theory, we compute the electrical properties of such pores in the absence and presence of nucleobases. Within a two-terminal geometry, we analyze the…

定量方法 · 定量生物学 2014-05-16 Hatef Sadeghi , S. Bailey , Colin J. Lambert

A strict method is used to calculate the current-voltage characteristics of a double-stranded DNA. A more reliable model considering the electrostatic potential drop along an individual DNA molecular wire between the contacts is considered…

介观与纳米尺度物理 · 物理学 2007-05-23 Weihua Mu , Zhongcan Ou-Yang

Trapping, linearization, and imaging of single molecule DNA is of broad interest to both biophysicists who study polymer physics and engineers who build nucleic acid analyzing methods such as optical mapping. In this study, single DNA…

Thermal conductivity of isolated single molecule DNA fragments is of importance for nanotechnology, but has not yet been measured experimentally. Theoretical estimates based on simplified (1D) models predict anomalously high thermal…

介观与纳米尺度物理 · 物理学 2015-05-20 Alexander V. Savin , Mikhail A. Mazo , Irina P. Kikot , Leonid I. Manevitch , Alexey V. Onufriev

Double-stranded DNA translocates through sufficiently large nanopores either in a linear, single-file fashion or in a folded hairpin conformation when captured somewhere along its length. We show that the folding state of DNA can be…

生物物理 · 物理学 2018-08-15 Niklas Ermann , Nikita Hanikel , Vivian Wang , Kaikai Chen , Ulrich F. Keyser

The influence of decoherence and bonding on the linear conductance of single double-stranded DNA molecules is examined by fitting a phenomenological statistical model developed recently (EPJB {\bf 68}, 237 (2009)) to experimental results.…

软凝聚态物质 · 物理学 2010-09-30 M. Zilly , O. Ujsaghy , D. E. Wolf

Synthesis of tri functional electrically conducting, optical and magnetic nano-chain of Nicore-Aushell has been discussed here. Our Investigation indicates that such material attached with biomolecule DNA in chain form will have great…

材料科学 · 物理学 2009-01-05 Madhuri Mandal , Kalyan Mandal