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相关论文: DNA double helices for single molecule electronics

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A rapid and low-cost method to sequence DNA would usher in a revolution in medicine. We propose and theoretically show the feasibility of a protocol for sequencing based on the distributions of transverse electrical currents of…

软凝聚态物质 · 物理学 2015-06-25 Johan Lagerqvist , Michael Zwolak , Massimiliano Di Ventra

An ideal nanofabrication method should allow the organization of nanoparticles and molecules with nanometric positional precision, stoichiometric control and well-defined orientation. The DNA origami technique has evolved into a highly…

We studied the electrical conductivity of DNA molecules with conducting atomic force microscopy as a function of the chemical nature of the substrate surfaces, the nature of the electrical contact, and the number of DNA molecules (from a…

材料科学 · 物理学 2009-11-10 Thomas Heim , Dominique Deresmes , Dominique Vuillaume

It has been suggested by several authors that nonlinear excitations, in particular solitary waves, could play a fundamental functional role in the process of DNA transcription, effecting the opening of the double chain needed for RNA…

其他定量生物学 · 定量生物学 2016-09-08 G. Gaeta

We present a first-principle study of the electronic and conduction properties of a few classes of nanowires constituted of guanine (G) molecules, self-assembled in different geometries. We first analyze the effect of the vertical…

软凝聚态物质 · 物理学 2009-11-10 Arrigo Calzolari , Rosa Di Felice , Elisa Molinari

DNA nanostructures are made using synthetic DNA strands, the sequences of which are designed such that they will self-assemble into the desired form by hybridization of complementary domains. Various structures and devices have been…

生物物理 · 物理学 2015-06-02 Katherine E. Dunn

The two strands of a DNA molecule with a repetitive sequence can pair into many different basepairing patterns. For perfectly periodic sequences, early bulk experiments of Poerschke indicate the existence of a sliding process, permitting…

生物大分子 · 定量生物学 2007-05-23 Richard A. Neher , Ulrich Gerland

The electrodynamic response of DNA in the millimeter wave range is investigated. By performing measurements under a wide range of humidity conditions and comparing the response of single strand DNA and double strand DNA, we show that the…

无序系统与神经网络 · 物理学 2015-06-24 M. Briman , N. P. Armitage , E. Helgren , G. Gruner

We propose two-terminal devices for DNA sequencing which consist of a metallic graphene nanoribbon with zigzag edges (ZGNR) and a nanopore in its interior through which the DNA molecule is translocated. Using the nonequilibrium Green…

介观与纳米尺度物理 · 物理学 2012-01-26 Kamal K. Saha , Marija Drndic , Branislav K. Nikolic

Intracellular positive ions neutralise negative charges on the phosphates of a DNA strand conferring greater strength on the hydrogen bonds that connect complementary strands into a double helix and so confer enhanced stability. Beyond a…

软凝聚态物质 · 物理学 2016-04-25 Arghya Maity , Amar Singh , Navin Singh

Because of DNA appealing features as perfect material, including minuscule size, defined structural repeat and rigidity, programmable DNA-mediated processing is a promising computing paradigm, which employs DNAs as information storing and…

生物物理 · 物理学 2015-08-17 Jian-Jun Shu , Qi-Wen Wang , Kian-Yan Yong , Fangwei Shao , Kee Jin Lee

Charge inversion of a DNA double helix by an oppositely charged flexible polyelectrolyte (PE) is considered. We assume that, in the neutral state of the DNA-PE complex, each of the DNA charges is locally compensated by a PE charge. When an…

软凝聚态物质 · 物理学 2009-11-07 T. T. Nguyen , B. I. Shklovskii

The dielectrophoresis method for trapping and attaching nanoscale double-stranded DNA between nanoelectrodes was developed. The method gives a high yield of trapping single or a few molecules only which enables transport measurements at the…

软凝聚态物质 · 物理学 2007-05-23 S. Tuukkanen , A. Kuzyk , J. J. Toppari , V. P. Hytonen , T. Ihalainen , P. Torma

DNA is an ideal candidate to organize matter on the nanoscale, primarily due to the specificity and complexity of DNA based interactions. Recent advances in this direction include the self-assembly of colloidal crystals using DNA grafted…

软凝聚态物质 · 物理学 2009-11-13 Nicholas A. Licata , Alexei V. Tkachenko

The aim of the present paper is the study of the entropic elasticity of the dsDNA molecule, having a cristallographic length L of the order of 10 to 30 persistence lengths A, when it is subject to spatial obstructions. We have not tried to…

软凝聚态物质 · 物理学 2009-11-11 C. Bouchiat

The translocation of a short DNA fragment through a nanopore is addressed when the perforated membrane contains an embedded electrode. Accurate numerical solutions of the coupled Poisson, Nernst-Planck, and Stokes equations for a realistic,…

软凝聚态物质 · 物理学 2017-06-29 Thomas Töws , Peter Reimann

We study the electric properties of single-stranded DNA molecules with hairpin-like shapes in the presence of a magnetic flux. It is shown that the current amplitude can be modulated by the applied field. The details of the electric…

介观与纳米尺度物理 · 物理学 2007-05-23 Juyeon Yi , Henri Orland

Nanopores -- nanosized holes that can transport ions and molecules -- are very promising devices for genomic screening, in particular DNA sequencing. Both solid-state and biological pores suffer from the drawback, however, that the channel…

This paper introduces the use of cable dynamics models as a means to explore the mechanics of DNA on long-length scales. It is on these length scales that DNA forms twisted and curved three-dimensional shapes known as supercoils and loops.…

生物物理 · 物理学 2007-05-23 Sachin Goyal , Todd Lillian , Noel C. Perkins , Edgar Meyhofer

Single T4-DNA molecules were confined in rectangular-shaped channels with a depth of 300 nm and a width in the range 150-300 nm casted in a poly(dimethylsiloxane) nanofluidic chip. The extensions of the DNA molecules were measured with…

生物物理 · 物理学 2009-11-13 Ce Zhang , Fang Zhang , Jeroen A. van Kan , Johan R. C. van der Maarel