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Chemical reactions in cell are subject to intense stochastic fluctuations. An important question is how the fundamental physiological behavior of cell is kept stable against those noisy perturbations. In this paper a stochastic model of…

分子网络 · 定量生物学 2009-11-13 Yurie Okabe , Masaki Sasai

Demographic noise has profound effects on evolutionary and population dynamics, as well as on chemical reaction systems and models of epidemiology. Such noise is intrinsic and due to the discreteness of the dynamics in finite populations.…

物理与社会 · 物理学 2015-05-14 Tobias Galla

We present simple classical dynamical models to address the question of introducing a stochastic nature in a time variable. These models include noise in the time variable but not in the "space" variable, which is opposite to the normal…

其他凝聚态物理 · 物理学 2007-05-23 Toru Ohira

A key goal of systems biology is the predictive mathematical description of gene regulatory circuits. Different approaches are used such as deterministic and stochastic models, models that describe cell growth and division explicitly or…

分子网络 · 定量生物学 2012-10-12 Rahul Marathe , Veronika Bierbaum , David Gomez , Stefan Klumpp

The response of neurons is highly sensitive to the stimulus. The stimulus can be associated with a direct injection in vitro experimentation (e.g., time dependent and independent inputs); or post-synaptic potentials resulting from the…

神经元与认知 · 定量生物学 2024-01-09 Afifurrahman , Mohd Hafiz Mohd , Farah Aini Abdullah

We investigate a nonlinear dynamical system which ``remembers'' preselected values of a system parameter. The deterministic version of the system can encode many parameter values during a transient period, but in the limit of long times,…

凝聚态物理 · 物理学 2009-10-31 M. L. Povinelli , S. N. Coppersmith , L. P. Kadanoff , S. R. Nagel , S. C. Venkataramani

Neuronal responses are conspicuously variable. We focus on one particular aspect of that variability: the precision of action potential timing. We show that for common models of noisy spike generation, elementary considerations imply that…

无序系统与神经网络 · 物理学 2009-10-31 Guillermo A. Cecchi , Mariano Sigman , Jose-Manuel Alonso , Luis Martinez , Dante R. Chialvo , Marcelo O. Magnasco

Neural spikes in the brain form stochastic sequences, i.e., belong to the class of pulse noises. This stochasticity is a counterintuitive feature because extracting information - such as the commonly supposed neural information of mean…

神经与进化计算 · 计算机科学 2015-03-31 Laszlo B. Kish , Claes-Goran Granqvist , Sergey M. Bezrukov , Tamas Horvath

While noise is generally associated with uncertainties and often has a negative connotation in engineering, living organisms have evolved to adapt to (and even exploit) such uncertainty to ensure the survival of a species or implement…

分子网络 · 定量生物学 2022-09-29 Corentin Briat , Mustafa Khammash

We introduce a deep learning model for speech denoising, a long-standing challenge in audio analysis arising in numerous applications. Our approach is based on a key observation about human speech: there is often a short pause between each…

声音 · 计算机科学 2020-10-26 Ruilin Xu , Rundi Wu , Yuko Ishiwaka , Carl Vondrick , Changxi Zheng

Adding noise to a sensory signal generally decreases human performance. However noise can improve performance too, due to a process called stochastic resonance (SR). This paradoxical effect may be exploited in psychophysical experiments, to…

神经元与认知 · 定量生物学 2017-11-15 Jeroen J. A. van Boxtel

Noise plays a fundamental role in a wide variety of physical and biological dynamical systems. It can arise from an external forcing or due to random dynamics internal to the system. It is well established that even weak noise can result in…

偏微分方程分析 · 数学 2019-08-06 Eric Forgoston , Richard O. Moore

The particle-in-cell numerical method of plasma physics balances a trade-off between computational cost and intrinsic noise. Inference on data produced by these simulations generally consists of binning the data to recover the particle…

等离子体物理 · 物理学 2022-02-03 John Donaghy , Kai Germaschewski

Neurons in the nervous system are submitted to distinct sources of noise, such as ionic-channel and synaptic noise, which introduces variability in their responses to repeated presentations of identical stimuli. This motivates the use of…

The effects of noise on memory in a linear recurrent network are theoretically investigated. Memory is characterized by its ability to store previous inputs in its instantaneous state of network, which receives a correlated or uncorrelated…

神经与进化计算 · 计算机科学 2025-10-02 JingChuan Guan , Tomoyuki Kubota , Yasuo Kuniyoshi , Kohei Nakajima

Stochastic resonance is a non-linear phenomenon, in which the sensitivity of signal detectors can be enhanced by adding random noise to the detector input. Here, we demonstrate that noise can also improve the information flux in recurrent…

神经元与认知 · 定量生物学 2018-11-30 Patrick Krauss , Karin Prebeck , Achim Schilling , Claus Metzner

The effect of stochasticity, in the form of Gaussian white noise, in a predator-prey model with two distinct time-scales is presented. A supercritical singular Hopf bifurcation yields a Type II excitability in the deterministic model. We…

动力系统 · 数学 2017-07-20 Susmita Sadhu

The effects of intrinsic noise on stochastic delay systems is studied within an expansion in the inverse system size. We show that the stochastic nature of the underlying dynamics may induce oscillatory behaviour in parameter ranges where…

分子网络 · 定量生物学 2015-05-13 Tobias Galla

Neural-network models of high-level brain functions such as memory recall and reasoning often rely on the presence of stochasticity. The majority of these models assumes that each neuron in the functional network is equipped with its own…

Analytic, first-principles performance modeling of distributed-memory applications is difficult due to a wide spectrum of random disturbances caused by the application and the system. These disturbances (commonly called "noise") destroy the…

性能 · 计算机科学 2020-06-25 Ayesha Afzal , Georg Hager , Gerhard Wellein