Noise in neurons is message-dependent
Abstract
Neuronal responses are conspicuously variable. We focus on one particular aspect of that variability: the precision of action potential timing. We show that for common models of noisy spike generation, elementary considerations imply that such variability is a function of the input, and can be made arbitrarily large or small by a suitable choice of inputs. Our considerations are expected to extend to virtually any mechanism of spike generation, and we illustrate them with data from the visual pathway. Thus, a simplification usually made in the application of information theory to neural processing is violated: noise {\sl is not independent of the message}. However, we also show the existence of {\sl error-correcting} topologies, which can achieve better timing reliability than their components.
Cite
@article{arxiv.cond-mat/0004492,
title = {Noise in neurons is message-dependent},
author = {Guillermo A. Cecchi and Mariano Sigman and Jose-Manuel Alonso and Luis Martinez and Dante R. Chialvo and Marcelo O. Magnasco},
journal= {arXiv preprint arXiv:cond-mat/0004492},
year = {2009}
}
Comments
6 pages,6 figures. Proceedings of the National Academy of Sciences (in press)