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As an injury heals, an embryo develops, or a carcinoma spreads, epithelial cells systematically change their shape. In each of these processes cell shape is studied extensively, whereas variation of shape from cell-to-cell is dismissed most…

Stochastic dynamics govern many important processes in cellular biology, and an underlying theoretical approach describing these dynamics is desirable to address a wealth of questions in biology and medicine. Mathematical tools exist for…

定量方法 · 定量生物学 2016-02-17 Iain G. Johnston , Nick S. Jones

When we try to solve a system of linear equations, we can consider a simple iterative algorithm in which an equation including only one variable is chosen at each step, and the variable is fixed to the value satisfying the equation. The…

离散数学 · 计算机科学 2015-06-03 Ryuhei Mori , Osamu Watanabe

An electro-chemo-mechanical phase-field formulation is developed to simulate pitting and stress corrosion in polycrystalline materials. The formulation incorporates dependencies of mechanical properties and corrosion potential on…

计算工程、金融与科学 · 计算机科学 2024-04-01 M. Makuch , S. Kovacevic , M. R. Wenman , E. Martínez-Pañeda

In these lecture notes I describe some of the main theoretical ideas emerged to explain the aging dynamics. This is meant to be a very short introduction to aging dynamics and no previous knowledge is assumed. I will go through simple…

统计力学 · 物理学 2009-11-11 Giulio Biroli

We study the long-time behaviour of the first-moment semigroup of a non conservative piecewise deterministic measure-valued stochastic process with support on R 2 + driven by a deterministic flow between random jump times, with a transition…

偏微分方程分析 · 数学 2024-03-20 Ignacio Madrid

Projection-based embedding offers a simple framework for embedding correlated wavefunction methods in density functional theory. Partitioning between the correlated wavefunction and density functional subsystems is performed in the space of…

化学物理 · 物理学 2018-10-16 Matthew Welborn , Frederick R. Manby , Thomas F. Miller

Given a quantum many-body system and the expectation-value dynamics of some operator, we study how this reference dynamics is altered due to a perturbation of the system's Hamiltonian. Based on projection operator techniques, we unveil that…

We investigate aging in glassy systems based on a simple model, where a point in configuration space performs thermally activated jumps between the minima of a random energy landscape. The model allows us to show explicitly a subaging…

统计力学 · 物理学 2009-10-31 Bernd Rinn , Philipp Maass , Jean-Philippe Bouchaud

We introduce a high dimensional symplectic map, modeling a large system consisting of weakly interacting chaotic subsystems, as a toy model to analyze the interplay between single-particle chaotic dynamics and particles interactions in…

混沌动力学 · 物理学 2011-11-10 Massimo Falcioni , Luigi Palatella , Simone Pigolotti , Lamberto Rondoni , Angelo Vulpiani

Aging remains a fundamental open problem in modern biology. Although there exist a number of theories on aging on the cellular scale, nearly nothing is known about how microscopic failures cascade to macroscopic failures of tissues, organs…

组织与器官 · 定量生物学 2017-07-10 Aylin Acun , Dervis Can Vural , Pinar Zorlutuna

Numerical studies are providing novel information on the physical processes associated to physical aging. The process of aging has been shown to consist in a slow process of explorations of deeper and deeper minima of the system potential…

软凝聚态物质 · 物理学 2009-11-07 Stefano Mossa , Giancarlo Ruocco , Francesco Sciortino , Piero Tartaglia

This work deals with the average scattering entropy of quantum graphs. We explore this concept in several distinct scenarios that involve periodic, aperiodic and random distribution of vertices of distinct degrees. In particular, we compare…

量子物理 · 物理学 2022-04-13 Alison A. Silva , Fabiano M. Andrade , D. Bazeia

Molten metallic nanoparticles have recently been used to construct graphene nanostructures with crystallographic edges. The mechanism by which this happens, however, remains unclear. Here, we present a simple model that explains how a…

介观与纳米尺度物理 · 物理学 2010-08-16 Sujit S. Datta

Recent experiments at the level of a single cell have shown that gene expression occurs in abrupt stochastic bursts. Further, in an ensemble of cells, the levels of proteins produced have a bimodal distribution. In a large fraction of…

软凝聚态物质 · 物理学 2009-11-07 Siddhartha Roy , Indrani Bose , Subhrangshu Sekhar Manna

Localized growth in driven materials is often governed by intermittent failure, yet how a material's history biases failure sites remains poorly understood. Using pause-restart experiments on chemical precipitate membranes, we quantify the…

斑图形成与孤子 · 物理学 2026-02-10 Amari Morris , Oliver Steinbock

Battery degradation is governed by complex and randomized cyclic conditions, yet existing modeling and prediction frameworks usually rely on rigid, unchanging protocols that fail to capture real-world dynamics. The stochastic electrical…

信号处理 · 电气工程与系统科学 2025-04-08 Yuqi Li , Han Zhang , Xiaofan Gui , Zhao Chen , Yu Li , Xiwen Chi , Quan Zhou , Shun Zheng , Ziheng Lu , Wei Xu , Jiang Bian , Liquan Chen , Hong Li

Laboratory and numerical corrosion experiments impose an electric potential on the metal surface, differing from natural corrosion conditions, where corrosion typically occurs in the absence of external current sources. In this work, we…

化学物理 · 物理学 2023-05-23 Tim Hageman , Carmen Andrade , Emilio Martínez-Pañeda

Although species longevity is subject to a diverse range of selective forces, the mortality curves of a wide variety of organisms are rather similar. We argue that aging and its universal characteristics may have evolved by means of a…

种群与进化 · 定量生物学 2013-02-01 Dervis Can Vural , Greg Morrison , L. Mahadevan

Lymphocyte populations, stimulated in vitro or in vivo, grow as cells divide. Stochastic models are appropriate because some cells undergo multiple rounds of division, some die, and others of the same type in the same conditions do not…

细胞行为 · 定量生物学 2021-12-02 Giulia Belluccini , Martín López-García , Grant Lythe , Carmen Molina-París