相关论文: Stability of adhesion clusters under constant forc…
We investigate the dynamics of cellular solidification patterns using three-dimensional phase-field simulations. The cells can organize into stable hexagonal patterns or exhibit unsteady evolutions. We identify the relevant secondary…
Mechanical forces acting on cell adhesion receptor proteins regulate a range of cellular functions by formation and rupture of non-covalent interactions with ligands. Typically, force decreases the lifetimes of intact complexes…
Collective oscillation of cells in a population has been reported under diverse biological contexts and with vastly different molecular constructs. Could there be common principles similar to those that govern spontaneous oscillation in…
The formation, movement and gluing of clusters can be described through a system of non local balance laws. Here, the well posedness of this system is obtained, as well as various stability estimates. Remarkably, qualitative properties of…
We study the onset of delamination blisters in a growing elastic sheet adhered to a flat stiff substrate. When the ends of the sheet are kept fixed, its growth arouses residual stresses that lead to delamination. This instability can be…
We analyze systems of clusters and interacting upon colliding---a collision between two clusters may lead to merging or fragmentation---and we also investigate the influence of additional spontaneous fragmentation events. We consider both…
To insight the relationships between the self-organizing structures of cells, such as the cell clusters, and the properties of biotissues is helpful in revealing the function and designing biomaterial. Traditional random foam model neglects…
Adhesive contact between a thin elastic sheet and a substrate in a liquid environment arises in a range of biological, physical and technological applications. By considering the dynamics of this process that naturally couples fluid flow,…
We present a unified classical treatment of partially constrained elastic rods. Partial constraints often entail singularities in both shapes and reactions. Our approach encompasses both sleeve and adhesion problems, and provides simple and…
Cell-cell adhesion is one the most fundamental mechanisms regulating collective cell migration during tissue development, homeostasis and repair, allowing cell populations to self-organize and eventually form and maintain complex tissue…
This model describes cluster aggregation in a stirred colloidal solution Interacting clusters compete for growth in this 'winner-takes-all' model; for finite assemblies, the largest cluster always wins, i.e. there is a uniform sediment. In…
Monolayer cluster growth in far-from-equilibrium systems is investigated by applying simulation and analytic techniques to minimal hard core particle (exclusion) models. The first model (I), for post-deposition coarsening dynamics, contains…
Using molecular dynamic simulation, we study the stretching of an adsorbed homopolymer in a poor solvent with one end held at a distance $z_e$ from the substrate. We measure the vertical force $f$ on the end of the chain as a function of…
Even the most regular stick-slip frictional sliding is always stochastic, with irregularity in both the intervals between slip events and the sizes of the associated stress drops. Applying small-amplitude oscillations to the shear force, we…
I introduce several simplified schemes for the approximation of the self-consistency condition of the dynamical cluster approximation. The applicability of the schemes is tested numerically using the fluctuation-exchange approximation as a…
Stochasticity is a defining feature of the pairwise forces governing interactions in biological systems-from molecular motors to cell-cell adhesion-yet its consequences on large-scale dynamics remain poorly understood. Here, we show that…
We study numerically how multiple deformable capsules squeeze into a constriction. This situation is largely encountered in microfluidic chips designed to manipulate living cells, which are soft entities. We use fully three-dimensional…
How multicellular life forms evolved out from unicellular ones constitutes a major problem in our understanding of the evolution of our biosphere. A recent set of experiments involving yeast cell populations has shown that selection for…
Many biological processes are supported by special molecules, called motor proteins or molecular motors, that transport cellular cargoes along linear protein filaments and can reversibly associate to their tracks. Stimulated by these…
Constitutive equations are derived for the viscoelastic behavior of filled elastomers at isothermal loading with finite strains. A particle-reinforced rubber is thought of as a composite where regions with low concentrations of junctions…