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Adhesive interactions between elastic structures such as graphene sheets, carbon nanotubes, and microtubules have been shown to exhibit hysteresis due to irrecoverable energy loss associated with bond breakage, even in static…

生物物理 · 物理学 2021-02-02 Edvin Memet , Feodor Hilitski , Zvonimir Dogic , L. Mahadevan

The interplay between gravitational and dispersive forces in a multi-streamed medium leads to an effect which is exposed in the present note as the genuine driving force of stabilization of large-scale structure. The conception of `adhesive…

天体物理学 · 物理学 2009-09-25 Thomas Buchert

This paper deals with the adhesive interaction arising between a cell circulating in the blood flow and the vascular wall. The purpose of this work is to investigate the effect of the blood flow velocity on the cell dynamics, and in…

偏微分方程分析 · 数学 2019-12-13 Christèle Etchegaray , Nicolas Meunier

Biological adhesion is a critical mechanical function of complex organisms operating at multiple scales. At the cellular scale, cell-cell adhesion is remarkably tunable to enable both cohesion and malleability during development,…

软凝聚态物质 · 物理学 2022-03-07 Dimitri Kaurin , Pradeep K. Bal , Marino Arroyo

We propose a model of mass-conserving heterogeneous nucleation to describe the dynamics of ligand-receptor binding in closed cellular compartments. When the ligand dissociation rate is small, competition among receptors for free ligands…

软凝聚态物质 · 物理学 2015-05-30 T. Chou , M. D'Orsogna

Inspired by motile cells in tissue formation, we find that active systems of self-aligning adhesive particles undergo ballistic aggregation through a flocking transition. This kinetic regime emerges when the cluster persistence length grows…

Focal adhesions are the loci of cellular adhesion to the extracellular matrix. At these sites, various integrins forge connections between the intracellular cytoskeleton and the outside world: large patches of multiple types of integrins…

生物物理 · 物理学 2021-03-10 Elizaveta A. Novikova , Cornelis Storm

We study the steady state of an assembly of microtubules in a confined volume, analogous to the situation inside a cell where the cell boundary forms a natural barrier to growth. We show that the dynamical equations for growing and…

亚细胞过程 · 定量生物学 2012-08-27 Bindu S. Govindan , William. B. Spillman,

We investigate a class of stochastic aggregation processes involving two types of clusters: active and passive. The mass distribution is obtained analytically for several aggregation rates. When the aggregation rate is constant, we find…

统计力学 · 物理学 2007-05-23 P. L. Krapivsky , E. Ben-Naim

Mechanical force regulates the formation and growth of cell-cell junctions. Cadherin is a prominent homotypic cell adhesion molecule that plays a crucial role in establishment of intercellular adhesion. It is known that the transmitted…

生物物理 · 物理学 2017-10-11 Mohammad Tehrani , Alireza Sarvestani

Stochastic chemical reaction or population dynamics in finite systems often terminates in an absorbing state. Yet in large spatially extended systems, the time to reach species extinction (or fixation) becomes exceedingly long. Tuning…

种群与进化 · 定量生物学 2025-11-17 Kenneth A. V. Distefano , Sara Shabani , Uwe C. Täuber

Experiments are carried out with a globally coupled, externally forced population of limit-cycle electrochemical oscillators with an approximately unimodal distribution of heterogeneities. Global coupling induces mutually entrained (at…

混沌动力学 · 物理学 2009-11-13 Istvan Z. Kiss , Yumei Zhai , John L. Hudson

The breakage of a polymer chain of segments, coupled by anharmonic bonds with applied constant external tensile force is studied by means of Molecular Dynamics simulation. We show that the mean life time of the chain becomes progressively…

软凝聚态物质 · 物理学 2015-05-27 J. Paturej , A. Milchev , V. G. Rostiashvili , T. A. Vilgis

Depletion-induced aggregation of rods enhanced by clustering is observed to produce a novel model of attractive pairs of rods separated by a line of spheres in a quasi-2D, vertically-shaken, granular gas of rods and spheres. We show that…

软凝聚态物质 · 物理学 2016-08-08 Gustavo M. Rodríguez-Liñán , Yuri Nahmad-Molinari , Gabriel Pérez-Ángel

We consider reversible breaking of adhesion bonds or folding of proteins under the influence of a constant external force. We discuss the stochastic properties of the unbinding/rebinding events and analyze their mean number and their…

软凝聚态物质 · 物理学 2009-11-13 Gregor Diezemann , Andreas Janshoff

Lifetimes of bound states of protein complexes or biomolecule folded states typically decrease when subject to mechanical force. However, a plethora of biological systems exhibit the counter-intuitive phenomenon of catch bonding, where…

生物大分子 · 定量生物学 2016-01-12 Shaon Chakrabarti , Michael Hinczewski , D. Thirumalai

The stability of the insulating regime of the Hubbard model on a $d$-dimensional lattice, which is characterized by an exponential decay of the Green's functions, is investigated in terms of a cluster expansion. This expansion for the…

凝聚态物理 · 物理学 2007-05-23 K. Ziegler

Irreversible diffusion limited cluster aggregation (DLCA) of hard spheres was simulated using Brownian cluster dynamics. Bound spheres were allowed to move freely within a specified range, but no bond breaking was allowed. The structure and…

软凝聚态物质 · 物理学 2009-03-25 Sujin Babu , Jean-Christophe Gimel , Taco Nicolai

Epithelial cell clusters often move collectively on a substrate. Mechanical signals play a major role in organizing this behavior. There are a number of experimental observations in these systems which await a comprehensive explanation.…

生物物理 · 物理学 2021-01-22 Youyuan Deng , Herbert Levine , Xiaoming Mao , Leonard M. Sander

By means of molecular dynamics, we study a model system for colloidal suspensions where the interaction is based on a competition between attraction and repulsion. At low temperatures the relaxation time $\tau$ first increases as a power…

软凝聚态物质 · 物理学 2009-11-10 A. de Candia , E. Del Gado , A. Fierro , N. Sator , A. Coniglio