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Left-right axis specification establishes embryonic laterality through asymmetric signaling cascades originating at the cellular scale. We previously reported the presence of a directionality bias in confined pairs of endothelial (and…

细胞行为 · 定量生物学 2026-03-31 Egun Im , Ghina Badih , Laetitia Kurzawa , Andreas Buttenschön , Calina Copos

Visual recognition takes a small fraction of a second and relies on the cascade of signals along the ventral visual stream. Given the rapid path through multiple processing steps between photoreceptors and higher visual areas, information…

神经元与认知 · 定量生物学 2014-04-28 Jedediah M. Singer , Joseph R. Madsen , William S. Anderson , Gabriel Kreiman

Can neural networks learn goal-directed behaviour using similar strategies to the brain, by combining the relationships between the current state of the organism and the consequences of future actions? Recent work has shown that recurrent…

神经元与认知 · 定量生物学 2021-01-21 Justin Jude , Matthias H. Hennig

Vital to primary visual processing, retinal circuitry shows many similar structures across a very broad array of species, both vertebrate and non-vertebrate, especially functional components such as lateral inhibition. This surprisingly…

神经与进化计算 · 计算机科学 2021-02-23 Ziyi Gong , Paul Munro

Neuromorphic computing uses brain-inspired principles to design circuits that can perform computational tasks with superior power efficiency to conventional computers. Approaches that use traditional electronic devices to create artificial…

应用物理 · 物理学 2020-07-14 J. Grollier , D. Querlioz , K. Y. Camsari , K. Everschor-Sitte , S. Fukami , M. D. Stiles

We propose a theory for ocular dominance (OD) patterns in mammalian primary visual cortex. This theory is based on the premise that OD pattern is an adaptation to minimize the length of intra-cortical wiring. Thus we can understand the…

软凝聚态物质 · 物理学 2007-05-23 Dmitri B. Chklovskii , Alexei A. Koulakov

Convolutional neural nets (convnets) trained from massive labeled datasets have substantially improved the state-of-the-art in image classification and object detection. However, visual understanding requires establishing correspondence on…

计算机视觉与模式识别 · 计算机科学 2015-03-10 Jonathan Long , Ning Zhang , Trevor Darrell

Convolutional networks are ubiquitous in deep learning. They are particularly useful for images, as they reduce the number of parameters, reduce training time, and increase accuracy. However, as a model of the brain they are seriously…

机器学习 · 计算机科学 2022-01-19 Roman Pogodin , Yash Mehta , Timothy P. Lillicrap , Peter E. Latham

The various types of retinal neurons are each positioned at their respective depths within the retina where they are believed to be assembled as orderly mosaics, in which like-type neurons minimize proximity to one another. Two common…

神经元与认知 · 定量生物学 2019-10-24 Patrick W. Keeley , Stephen J. Eglen , Benjamin E. Reese

Neurons in the visual cortex are correlated in their variability. The presence of correlation impacts cortical processing because noise cannot be averaged out over many neurons. In an effort to understand the functional purpose of…

机器学习 · 计算机科学 2018-04-04 Shamak Dutta , Bryan Tripp , Graham Taylor

Why do moving objects appear rigid when projected retinal images are deformed nonrigidly? We used rotating rigid objects that can appear rigid or non-rigid to test whether shape features contribute to rigidity perception. When two circular…

神经元与认知 · 定量生物学 2023-04-12 Akihito Maruya , Qasim Zaidi

The mirror neuron theory that has enjoyed continued validations was developed with no particular attention to the phenomenon of the vision. Understandably the perception of vision has always been thought to happen, naturally, as that for…

神经元与认知 · 定量生物学 2022-03-01 Jahan N. Schad

Sensory perception originates from the responses of sensory neurons, which react to a collection of sensory signals linked to various physical attributes of a singular perceptual object. Unraveling how the brain extracts perceptual…

神经元与认知 · 定量生物学 2025-10-27 Zhichao Zhu , Yang Qi , Wenlian Lu , Jianfeng Feng

Neuronal networks constitute a special class of dynamical systems, as they are formed by individual geometrical components, namely the neurons. In the existing literature, relatively little attention has been given to the influence of…

神经元与认知 · 定量生物学 2015-05-13 Sebastian Ahnert , Luciano da Fontoura Costa

Plasticity is one of the most important properties of the nervous system, which enables animals to adjust their behavior to the ever-changing external environment. Changes in synaptic efficacy between neurons constitute one of the major…

神经元与认知 · 定量生物学 2018-01-23 Taishi Iwasaki , Hideitsu Hino , Masami Tatsuno , Shotaro Akaho , Noboru Murata

Convolutional neural networks (CNNs) have been shown to be state-of-the-art models for visual cortical neurons. Cortical neurons in the primary visual cortex are sensitive to contextual information mediated by extensive horizontal and…

计算机视觉与模式识别 · 计算机科学 2025-03-03 Isaac Lin , Tianye Wang , Shang Gao , Shiming Tang , Tai Sing Lee

For 20 years the beautiful structure in the grid cell code has presented an attractive puzzle: what computation do these representations subserve, and why does it manifest so curiously in neurons. The first question quickly attracted an…

神经元与认知 · 定量生物学 2026-03-06 William Dorrell , James C. R. Whittington

It has been argued that the emergence of roughly periodic orientation preference maps (OPMs) in the primary visual cortex (V1) of carnivores and primates can be explained by a so-called statistical connectivity model. This model assumes…

神经元与认知 · 定量生物学 2023-10-18 Manuel Schottdorf , Stephen J. Eglen , Fred Wolf , Wolfgang Keil

For long it has been known that specific patterns of folding are necessary for an optimally functioning brain. For instance, lissencephaly and polymicrogyria can lead to severe mental retardation, short life expectancy, epileptic seizures,…

生物物理 · 物理学 2020-04-03 Lucas da Costa Campos , Raphael Hornung , Gerhard Gompper , Jens Elgeti , Svenja Caspers

We show that, in contrast to classical random graph models, many real-world complex systems -- including a variety of biological regulatory networks and technological networks such as the internet -- spontaneously self-organize to a richly…

无序系统与神经网络 · 物理学 2007-05-23 B. D. MacArthur , J. W. Anderson