相关论文: A chemically driven fluctuating ratchet model for …
We consider the motion of a overdamped Brownian particle in periodic asymmetric potential with space dependent friction coefficient. In the presence of external time periodic forcing, the system shows multiple current reversals on varying…
Living cells adapt and respond actively to the mechanical properties of their environment. In addition to biochemical mechanotransduction, evidence exists for a myosin-dependent, purely mechanical sensitivity to the stiffness of the…
Inspired by recent experiments on the dynamics of particles and polymers in artificial cytoskeletons and in cells, we introduce a modified Langevin equation for a particle in an environment that is a viscoelastic medium and that is brought…
Feynman's ratchet is a microscopic machine in contact with two heat reservoirs, at temperatures $T_A$ and $T_B$, that was proposed by Richard Feynman to illustrate the second law of thermodynamics. In equilibrium ($T_A=T_B$), thermal…
We derive a mode-coupling theory (MCT) to describe the dynamics of tracer particles in dense systems of active Brownian particles (ABPs) in two spatial dimensions. The ABP undergo translational and rotational Brownian dynamics, and are…
Two simple (rotator and one-particle) mechanistic models are suggested to describe simultaneously at a minimal level of sophistication two basic functions of F$_1$-ATPase: a motor regime driven by ATP hydrolysis and its inverted function as…
A molecular motor is made of either a single macromolecule or a macromolecular complex. Just like their macroscopic counterparts, molecular motors "transduce" input energy into mechanical work. All the nano-motors considered here operate…
Cytoskeletal networks, which are essentially motor-filament assemblies, play a major role in many developmental processes involving structural remodeling and shape changes. These are achieved by nonequilibrium self-organization processes…
Autonomous active Brownian ratchets rectify active Brownian particle motion solely by means of a spatially modulated but stationary activity, without external forces. We argue that such ratcheting requires at least a two-dimensional…
Biochemistry and mechanics are closely coupled in cell adhesion. At sites of cell-matrix adhesion, mechanical force triggers signaling through the Rho-pathway, which leads to structural reinforcement and increased contractility in the actin…
The actomyosin cytoskeleton, a protein assembly comprising actin fibers and the myosin molecular motor, drives various cellular dynamics through contractile force generation at high densities. However, the relationship between the density…
A light-driven molecular motor system is investigated using a multi-state Brownian ratchet model described by a single effective coordinate with multiple electronic states in a dissipative environment. The rotational motion of the motor…
The Kinesin family of motor proteins are involved in a variety of cellular processes that transport materials and generate force. With recent advances in experimental techniques, such as optical tweezers which can probe individual…
A novel equality relating the rate of energy dissipation to a degree of violation of the fluctuation-response relation (FRR) in nonequilibrium Langevin systems is described. The FRR is a relation between the correlation function of the…
Relevance of mode coupling to energy/information transfer during protein function, particularly in the context of allosteric interactions is widely accepted. However, existing evidence in favor of this hypothesis comes essentially from…
Brownian information engines can extract work from thermal fluctuations by utilizing information. So far, the studies on Brownian information engines consider the system in a thermal bath; however, many processes in nature occur in a…
We address the question of how interacting active systems in a non-equilibrium steady-state respond to an external perturbation. We establish an extended fluctuation-dissipation theorem for Active Brownian Particles (ABP) which highlights…
A simple tight-coupling model of a molecular chemical engine is proposed. The efficiency of the chemical engine and its average velocity can be explicitly calculated. The diffusion constant is evaluated approximately using the fluctuation…
We present a quantitative analysis of recent data on the kinetics of ATP hydrolysis, which has presented a puzzle regarding the load dependence of the Michaelis constant. Within the framework of coarse grained two-state ratchet models, our…
We present a Brownian dynamics simulation of the bacterial Stirling engine studied by Krishnamurthy et al., Nat. Phys. 12, 1134 (2016). In their experimental setup, an overdamped colloid in an optical trap with time-modulated stiffness…