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The fluctuation theorem is a representative theorem in non-equilibrium statistical physics actively studied in the 1990's. Relating to entropy production in non-equilibrium states, the theorem has been used to estimate the driving power of…

生物物理 · 物理学 2018-07-04 Kumiko Hayashi

The stochastic driving force exerted by a single molecular motor (e.g., a kinesin, or myosin) moving on a periodic molecular track (microtubule, actin filament, etc.) is discussed from a general viewpoint open to experimental test. An…

统计力学 · 物理学 2009-10-31 Michael E. Fisher , Anatoly B. Kolomeisky

We introduce an alternative route for obtaining reliable cyclic engines, based on interacting Brownian particles under time-periodic drivings. General expressions for the thermodynamic fluxes, such as power and heat, are obtained using the…

The movement of a Brownian particle in a fluctuating two-state periodic potential is investigated. At high transition rate, we use a perturbation method to obtain the analytical solution of the model. It is found that the net current is a…

生物物理 · 物理学 2007-09-17 Bao-Quan Ai , Liqiu Wang , Liang-Gang Liu

We study a Brownian motor, based on cold atoms in optical lattices, where atomic motion can be induced in a controlled manner in an arbitrary direction, by rectification of isotropic random fluctuations. In contrast with ratchet mechanisms,…

The precise details of how myosin-V coordinates the biochemical reactions and mechanical motions of its two head elements to engineer effective processive molecular motion along actin filaments remain unresolved. We compare a quantitative…

生物大分子 · 定量生物学 2009-11-13 K. I. Skau , R. B. Hoyle , M. S Turner

In this work, we study in detail the distribution of stochastic forces generated by the molecular motors activity, in the actin cortex of pre-muscular cells. By combining active and passive rheology experiments, performed on the same…

生物物理 · 物理学 2019-12-10 P. Bohec , J. Tailleur , F. van Wijland , A. Richert , F. Gallet

We present a mode-coupling theory (MCT) for the high-density dynamics of two-dimensional spherical active Brownian particles (ABP). The theory is based on the integration-through-transients (ITT) formalism and hence provides a starting…

软凝聚态物质 · 物理学 2017-12-20 Alexander Liluashvili , Jonathan Onody , Thomas Voigtmann

We demonstrate a Brownian motor, based on cold atoms in optical lattices, where isotropic random fluctuations are rectified in order to induce controlled atomic motion in arbitrary directions. In contrast to earlier demonstrations of…

In this work, we study the dynamics of a single active Brownian particle, as well as the collective behavior of interacting active Brownian particles, in a fluctuating heterogeneous environment. We employ a variant of the diffusing…

软凝聚态物质 · 物理学 2022-01-05 S. M. J. Khadem , N. H. Siboni , S. H. L. Klapp

The molecular motor myosin V exhibits a wide repertoire of pathways during the stepping process, which is intimately connected to its biological function. The best understood of these is hand-over-hand stepping by a swinging lever arm…

生物大分子 · 定量生物学 2013-10-28 Michael Hinczewski , Riina Tehver , D. Thirumalai

An asymmetric Brownian particle subjected to an external time-dependent force may acquire a net drift velocity, and thus operate as a motor or ratchet, even if the external force is represented by an unbiased time-periodic function or by a…

统计力学 · 物理学 2018-11-14 A. V. Plyukhin

In order to optimize the directed motion of an inertial Brownian motor, we identify the operating conditions that both maximize the motor current and minimize its dispersion. Extensive numerical simulation of an inertial rocked ratchet…

统计力学 · 物理学 2009-11-11 Lukasz Machura , Marcin Kostur , Fabio Marchesoni , Peter Talkner , Peter Hänggi , Jerzy Luczka

In contrast to the classical concept of a Carnot engine that alternates contact between heat baths of different temperatures, naturally occurring processes usually harvest energy from anisotropy, being exposed simultaneously to chemical and…

系统与控制 · 电气工程与系统科学 2022-12-27 Olga Movilla Miangolarra , Amirhossein Taghvaei , Yongxin Chen , Tryphon T. Georgiou

Myosin motor is the machine, which performs mechanical work in the course of adenosine triphosphate molecule hydrolysis and myosin head conformations accompanying this process. For displacement of individual fragments of large molecule…

生物大分子 · 定量生物学 2007-05-23 E. V. Rosenfeld

We present a study on filamentous actin solutions containing heavy meromyosin subfragments of myosin II motor molecules. We focus on the viscoelastic phase behavior and internal dynamics of such networks during ATP depletion. Upon…

生物物理 · 物理学 2007-05-23 Joerg Uhde , Manfred Keller , Erich Sackmann , Andrea Parmeggiani , Erwin Frey

Molecular motors fulfill critical functions within all living beings. Understanding their underlying working principles is therefore of great interest. Here we develop a simple model inspired by the two-component biomolecular motor Fo-F1…

统计力学 · 物理学 2024-12-30 Mathis Grelier , David A. Sivak , Jannik Ehrich

Biological activity gives rise to non-equilibrium fluctuations in the cytoplasm of cells; however, there are few methods to directly measure these fluctuations. Using a reconstituted actin cytoskeleton, we show that the bending dynamics of…

软凝聚态物质 · 物理学 2009-11-13 C. P. Brangwynne , G. H. Koenderink , F. C. MacKintosh , D. A. Weitz

The transport of interacting Brownian particles in a periodic asymmetric (ratchet) substrate is studied numerically. In a zero-temperature regime, the system behaves as a reversible step motor, undergoing multiple sign reversals of the…

统计力学 · 物理学 2008-12-31 Rogério M. da Silva , Clécio C. de Souza Silva , Sérgio Coutinho

We present a model of an ATP-fueled molecular machine which push a polymer through a pore channel. The machine acts between two levels (working-waiting), and the working one remains active for a fixed time giving a constant force. The…

软凝聚态物质 · 物理学 2012-02-24 Alessandro Fiasconaro , Juan José Mazo , Fernando Falo