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A stochastic model of intracellular calcium oscillations is analytically studied. The governing master equation is expanded under the linear noise approximation and a closed prediction for the power spectrum of fluctuations analytically…

统计力学 · 物理学 2013-07-15 Laura Cantini , Claudia Cianci , Duccio Fanelli , Emma Massi , Luigi Barletti

According to the conventional approach to model neural ensembles the extracellular environment has fixed ionic concentrations. However, in many cases the extracellular concentration of potassium ions can not be regarded as constant. That…

无序系统与神经网络 · 物理学 2015-05-13 D. E. Postnov , F. Müller , R. B. Schuppner , L. Schimansky-Geier

We propose a simple discrete stochastic model for calcium dynamics in living cells. Specifically, the calcium concentration distribution is assumed to give rise to a set of probabilities for the opening/closing of channels which release…

patt-sol · 物理学 2009-10-31 Markus Baer , Martin Falcke , Herbert Levine , Lev S. Tsimring

It is known that curvature relation plays a key role in the propagation of two-dimensional waves in an excitable model. Such a relation is believed to obey the eikonal equation for typical excitable models (e.g., the FitzHugh-Nagumo (FHN)…

动力系统 · 数学 2014-02-20 Wenjun Zhang , James Sneyd , Je-Chiang Tsai

The Fitzhugh-Nagumo equations have been used as a caricature of the Hodgkin-Huxley equations of neuron firing to better understand the essential dynamics of the interaction of the membrane potential and the restoring force and to capture,…

神经元与认知 · 定量生物学 2007-05-23 F. Berezovskaya , E. Camacho , S. Wirkus , G. Karev

The calcium transport in biological systems is modelled as a reaction-diffusion process. Nonlinear calcium waves are then simulated using a stochastic cellular automaton whose rules are derived from the corresponding coupled partial…

斑图形成与孤子 · 物理学 2010-03-30 Xin-She Yang

We study reaction-diffusion waves on curved two-dimensional surfaces, and determine the influence of curvature upon the nucleation and propagation of spatially localized waves in an excitable medium modelled by the generic FitzHugh-Nagumo…

斑图形成与孤子 · 物理学 2014-08-13 Frederike Kneer , Eckehard Schöll , Markus A. Dahlem

Noise induced Brownian dynamics in underdamped medium is studied numerically to understand the firing time of excitable systems. By considering Brownian particles that move in underdamped medium, we study how the first arrival time behaves…

统计力学 · 物理学 2018-10-10 Solomon F. Duki , Mesfin A. Taye

We examine traveling-wave solutions on a regular ring network with one additional long-range link that spans a distance d. The nodes obey the FitzHugh-Nagumo kinetics in the excitable regime. The additional shortcut induces a plethora of…

适应与自组织系统 · 物理学 2015-06-23 Thomas Isele , Benedikt Hartung , Philipp Hövel , Eckehard Schöll

The presynaptic free calcium dynamics of neurons due to various stimulation protocols is investigated in a mathematical model. The model includes calcium influx through voltage-dependent calcium channels, calcium buffering by endogenous and…

生物物理 · 物理学 2007-05-23 Frido Erler , Michael Meyer-Hermann , Gerhard Soff

We consider a stochastic version of an excitable system based on the Morris-Lecar model of a neuron, in which the noise originates from stochastic Sodium and Potassium ion channels opening and closing. One can analyze neural excitability in…

神经元与认知 · 定量生物学 2015-06-15 Jay M. Newby , Paul C. Bressloff , James P. Keener

The FitzHugh-Nagumo equation, originally conceived in neuroscience during the 1960s, became a key model providing a simplified view of excitable neuron cell behavior. Its applicability, however, extends beyond neuroscience into fields like…

斑图形成与孤子 · 物理学 2025-01-08 Daniel Cebrián-Lacasa , Pedro Parra-Rivas , Daniel Ruiz-Reynés , Lendert Gelens

Stochastic transitions between discrete microscopic states play an important role in many physical and biological systems. Often, these transitions lead to fluctuations on a macroscopic scale. A classic example from neuroscience is the…

统计力学 · 物理学 2024-02-20 Lukas Ramlow , Benjamin Lindner

The Fitzhugh-Nagumo neuronal model is used to explore the influence of the electric field on thermosensitive neurons' dynamics. This study investigates how the electric field affects polarization modulation in cell media induced by changes…

混沌动力学 · 物理学 2025-02-13 Ediline L. F. Nguessap , Fernando F. Ferreira , Antonio C. Roque

Brain operates at remarkably low signal power. It has been noted that noise may play a constructive role in neural networks and facilitate the subthreshold signaling. The process of spiking pattern excitation at the characteristic neuronal…

神经元与认知 · 定量生物学 2024-08-12 Mariia Sorokina

We consider the coaction of two distinct noise sources on the activation process of a single and two interacting excitable units, which are mathematically described by the Fitzhugh-Nagumo equations. We determine the most probable activation…

混沌动力学 · 物理学 2016-04-19 Igor Franović , Kristina Todorović , Matjaz Perc , Nebojša Vasović , Nikola Burić

Linearization around unstable travelling waves in excitable systems can be used to approximate strength-extent curves in the problem of initiation of excitation waves for a family of spatially confined perturbations to the rest state. This…

斑图形成与孤子 · 物理学 2020-04-08 Christopher D. Marcotte , Vadim N. Biktashev

Calcium dynamics is the highly responsible for intracellular electrical (action potential) and chemical (neurotransmitter) signaling in neuron cell. The Mathematical modeling of calcium dynamics in neurons lead to the reaction diffusion…

细胞行为 · 定量生物学 2013-01-08 Amrita tripathi , Neeru Adlakha

We propose to introduce a new stochastic process in molecular dynamics in order to improve the description of the nucleon emission process from a hot nucleus. We give momentum fluctuations originating from the momentum width of the nucleon…

核理论 · 物理学 2008-11-26 Akira Ono , Hisashi Horiuchi

We investigate the dynamics of single microparticles immersed in water that are driven out of equilibrium in the presence of an additional external colored noise. As a case study, we trap a single polystyrene particle in water with optical…

统计力学 · 物理学 2014-09-17 Pau Mestres , Ignacio A. Martinez , Antonio Ortiz-Ambriz , Raul A. Rica , Edgar Roldan
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