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We propose the following simple stochastic model for phylogenetic trees. New types are born and die according to a birth and death chain. At each birth we associate a fitness to the new type sampled from a fixed distribution. At each death…

概率论 · 数学 2013-06-29 T. M. Liggett , R. B. Schinazi

For birth and death chains, we derive bounds on the spectral gap and mixing time in terms of birth and death rates. Together with the results of Ding et al. in 2010, this provides a criterion for the existence of a cutoff in terms of the…

概率论 · 数学 2013-04-17 Guan-Yu Chen , Laurent Saloff-Coste

Genomic evolution can be viewed as string-editing processes driven by mutations. An understanding of the statistical properties resulting from these mutation processes is of value in a variety of tasks related to biological sequence data,…

信息论 · 计算机科学 2018-12-07 Hao Lou , Farzad Farnoud , Moshe Schwartz , Jehoshua Bruck

Which factors govern the evolution of mutation rates and emergence of species? Here, we address this question using a first principles model of life where population dynamics of asexual organisms is coupled to molecular properties and…

种群与进化 · 定量生物学 2009-11-13 Muyoung Heo , Louis Kang , Eugene I. Shakhnovich

Good generative models should not only synthesize high quality data, but also utilize interpretable representations that aid human understanding of their behavior. However, it is difficult to measure objectively if and to what degree…

机器学习 · 计算机科学 2025-04-09 Daniel Galperin , Ullrich Köthe

Phylogenetic trees describe the relationships between species in the evolutionary process, and provide information about the rates of diversification. To understand the mechanisms behind macroevolution, we consider a class of multitype…

种群与进化 · 定量生物学 2024-10-07 Mingqi He , Sophie Hautphenne , Yao-ban Chan

Populations are often subject to catastrophes that cause mass removal of individuals. Many stochastic growth models have been considered to explain such dynamics. Among the results reported, it has been considered whether dispersion…

概率论 · 数学 2023-08-21 F. Duque , V. V. Junior , F. P. Machado , A. Roldan-Correa

Exact string matching has been a fundamental problem in computer science for decades because of many practical applications. Some are related to common procedures, such as searching in files and text editors, or, more recently, to more…

数据结构与算法 · 计算机科学 2019-07-29 Konstantinos F. Xylogiannopoulos

We derive tractable criteria for the consistency of Bayesian tree reconstruction procedures, which constitute a central class of algorithms for inferring common ancestry among DNA sequence samples in phylogenetics. Our results encompass…

统计理论 · 数学 2025-08-05 Alisa Kirichenko , Luke J. Kelly , Jere Koskela

Grouped data are commonly encountered in applications. The Bernstein polynomial model is proposed as an approximate model in this paper for estimating a univariate density function based on grouped data. The coefficients of the Bernstein…

统计方法学 · 统计学 2015-07-21 Zhong Guan

We present an elementary model of random size varying population given by a stationary continuous state branching process. For this model we compute the joint distribution of: the time to the most recent common ancestor, the size of the…

概率论 · 数学 2010-09-07 Yu-Ting Chen , Jean-François Delmas

Min-entropy sampling gives a bound on the min-entropy of a randomly chosen subset of a string, given a bound on the min-entropy of the whole string. K\"onig and Renner showed a min-entropy sampling theorem that holds relative to quantum…

量子物理 · 物理学 2011-07-18 Jürg Wullschleger

The planted bisection model is a random graph model in which the nodes are divided into two equal-sized communities and then edges are added randomly in a way that depends on the community membership. We establish necessary and sufficient…

概率论 · 数学 2020-07-14 Elchanan Mossel , Joe Neeman , Allan Sly

Predicting an individual's aging trajectory is a central challenge in preventative medicine and bioinformatics. While machine learning models can predict chronological age from biomarkers, they often fail to capture the dynamic,…

机器学习 · 计算机科学 2025-08-14 Nazira Dunbayeva , Yulong Li , Yutong Xie , Imran Razzak

We consider diploid bi-parental analogues of Cannings models: in a population of fixed size $N$ the next generation is composed of $V_{i,j}$ offspring from parents $i$ and $j$, where $V=(V_{i,j})_{1\le i\neq j \le N}$ is a (jointly)…

概率论 · 数学 2018-03-29 Matthias Birkner , Huili Liu , Anja Sturm

We investigate Eigen's model for the evolution of the genetic code of microorganisms using a novel method based on population dynamics analysis. This model, for a given number of offspring, determines long-term survival as a function of the…

种群与进化 · 定量生物学 2024-06-21 Hermano Velten , Carlos Felipe Pinheiro , Alcides Castro e Silva

We consider two versions of stochastic population models with mutation and selection. The first approach relies on a multitype branching process; here, individuals reproduce and change type (i.e., mutate) independently of each other,…

种群与进化 · 定量生物学 2009-02-19 E. Baake , R. Bialowons

Increasing pressures on the environment are generating an ever-increasing need to manage animal and plant populations sustainably, and to protect and rebuild endangered populations. Effective management requires reliable mathematical…

统计方法学 · 统计学 2009-09-29 Stephen T. Buckland , Ken B. Newman , Carmen Fernández , Len Thomas , John Harwood

We develop the qualitative theory of the solutions of the McKendrick partial differential equation of population dynamics. We calculate explicitly the weak solutions of the McKendrick equation and of the Lotka renewal integral equation with…

种群与进化 · 定量生物学 2007-05-23 Rui Dilao , Abdelkader Lakmeche

Under mild non-degeneracy assumptions on branching rates in each generation, we provide a criterion for almost-sure extinction of a multi-type branching process with time-dependent branching rates. We also provide a criterion for the total…

概率论 · 数学 2018-11-22 Dmitry Dolgopyat , Pratima Hebbar , Leonid Koralov , Mark Perlman
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