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Deep neural networks (DNNs) enhance the accuracy and efficiency of reconstructing key parameters from time-resolved photon arrival signals recorded by single-photon detectors. However, the performance of conventional backpropagation-based…

机器学习 · 计算机科学 2025-04-15 Zhenya Zang , Xingda Li , David Day Uei Li

Nuclear magnetic resonance (NMR) imaging with shallow nitrogen-vacancy (NV) centers in diamond offers an exciting route toward sensitive and localized chemical characterization at the nanoscale. Remarkable progress has been made to combat…

Fundamental understanding of ionic transport at the nanoscale is essential for developing biosensors based on nanopore technology and new generation high-performance nanofiltration membranes for separation and purification applications. We…

In this paper, we present an accurate and robust scaling operator based on material optical thickness (OT) for the least-squares spherical harmonics (LSP$_N$) method for solving neutron transport problems. LSP$_N$ without proper scaling is…

计算物理 · 物理学 2017-05-17 Weixiong Zheng , Ryan G. McClarren

Superconducting Nanowire Single-Photon Detectors (SNSPDs) are key building blocks for photonic quantum technologies due to their ability to detect single photons with ultra-high efficiency, low dark counts and fast temporal resolution.…

Rare earth cerium oxide (ceria) nanoparticles are stabilized using end-functional phosphonated-PEG oligomers. The complexation process and structure of the resulting hybrid core-shell singlet nanocolloids are described, characterized and…

软凝聚态物质 · 物理学 2008-04-23 L. Qi , A. Sehgal , J. -C. Castaing , J. -P. Chapel , J. Fresnais , J. -F. Berret , F. Cousin

Single-beam scanning microscopy (SBSM) is one of the most robust strategies for commercial optical systems. Although structured illumination combined with Fourier-domain spatial spectrum fusion can enhance SBSM resolution beyond the…

光学 · 物理学 2025-07-15 Yongtao Liu , Tianxiao Wu , Xiao Zhou , Fan Wang

Orbital angular momentum (OAM) recognition of vortex beams is critical for applications ranging from optical communications to quantum technologies. However, conventional approaches designed for free-space propagation struggle when light…

Nanopore sequencing is an emerging DNA sequencing technology that has been proposed for use in DNA storage systems. We propose the noisy nanopore channel model for nanopore sequencing. This model captures duplications, inter-symbol…

信息论 · 计算机科学 2022-05-10 Brendon McBain , Emanuele Viterbo , James Saunderson

Mesoporous silica nanoparticles (MSNPs) have many potential applications in biomedical fields. However, when MSNPs are exposed to plasma, protein adsorption leads to opsonization and decreases blood circulation time. A new multifunctional…

Spectroscopy requires high-precision wavelength discrimination but typically requires bulky, alignment-sensitive instrumentation. To address this, we present a compact computational spectrometer built from a single germanium PN photodiode.…

Since their inception, superconducting nanowire single-photon detectors have been enabling quantum optical applications and the rise of the photonic quantum industry. The evolution in the detector design and read-out strategies has led to…

量子物理 · 物理学 2024-12-19 Lorenzo Stasi , Towsif Taher , Giovanni V. Resta , Hugo Zbinden , Rob Thew , Félix Bussières

Double-stranded DNA translocates through sufficiently large nanopores either in a linear, single-file fashion or in a folded hairpin conformation when captured somewhere along its length. We show that the folding state of DNA can be…

生物物理 · 物理学 2018-08-15 Niklas Ermann , Nikita Hanikel , Vivian Wang , Kaikai Chen , Ulrich F. Keyser

Surface enhanced Raman scattering (SERS) is optically sensitive and chemically specific to detect single molecule spectroscopic signatures. Facilitating this capability in optically-trapped nanoparticles at low laser power remains a…

光学 · 物理学 2021-09-10 Sunny Tiwari , Utkarsh Khandelwal , Vandana Sharma , G. V. Pavan Kumar

In recent years, magnetic particle spectroscopy (MPS) has become a highly sensitive and versatile sensing technique for quantitative bioassays. It relies on the dynamic magnetic responses of magnetic nanoparticles (MNPs) for the detection…

Nanopores -- nanosized holes that can transport ions and molecules -- are very promising devices for genomic screening, in particular DNA sequencing. Both solid-state and biological pores suffer from the drawback, however, that the channel…

Given a graph with a source vertex $s$, the Single Source Replacement Paths (SSRP) problem is to compute, for every vertex $t$ and edge $e$, the length $d(s,t,e)$ of a shortest path from $s$ to $t$ that avoids $e$. A Single-Source Distance…

数据结构与算法 · 计算机科学 2021-07-01 Davide Bilò , Sarel Cohen , Tobias Friedrich , Martin Schirneck

In single-molecule super-resolution microscopy, engineered point-spread functions (PSFs) are designed to efficiently encode new molecular properties, such as 3D orientation, into complex spatial features captured by a camera. To fully…

图像与视频处理 · 电气工程与系统科学 2019-07-16 Hesam Mazidi , Eshan S. King , Oumeng Zhang , Arye Nehorai , Matthew D. Lew

Electrokinetic force has been the major choice for driving the translocation of molecules through a nanopore. However, the use of this approach is limited by an uncontrollable translocation speed, resulting in non-uniform conductance…

应用物理 · 物理学 2024-04-22 Jianxin Yang , Tianle Pan , Zhenming Xie , Wu Yuan , Ho-Pui Ho

Single-image HDR reconstruction aims to recover high dynamic range radiance from a single low dynamic range (LDR) input, but remains highly ill-posed due to detail saturation in over-exposed regions and noise amplification in under-exposed…

计算机视觉与模式识别 · 计算机科学 2026-05-05 Aoyu Liu , Zhen Liu , Ziyi Wang , Dian Chen , Bing Zeng , Shuaicheng Liu