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P-splines provide a flexible and computationally efficient smoothing framework and are commonly used for derivative estimation in functional data. Including an additive penalty term in P-splines has been shown to improve estimates of…

统计方法学 · 统计学 2026-02-24 Yueyun Zhu , Steven Golovkine , Norma Bargary , Andrew J. Simpkin

Existing computationally efficient methods for penalized likelihood GAM fitting employ iterative smoothness selection on working linear models (or working mixed models). Such schemes fail to converge for a non-negligible proportion of…

统计方法学 · 统计学 2015-11-13 Simon N. Wood

Fitting statistical models to spatiotemporal data requires finding the right balance between imposing smoothness and following the data. In the context of p-splines, we propose a Bayesian framework for choosing the smoothing parameter which…

应用统计 · 统计学 2013-10-30 A. W. Bowman , L. Evers , D. Molinari , W. R. Jones , M. J. Spence

We present an energy-stable scheme for simulating the incompressible Navier-Stokes equations based on the generalized Positive Auxiliary Variable (gPAV) framework. In the gPAV-reformulated system the original nonlinear term is replaced by a…

计算物理 · 物理学 2020-07-15 L. Lin , N. Ni , Z. Yang , S. Dong

This paper focuses on the problem of modeling and estimating interaction effects between covariates and a continuous treatment variable on an outcome, using a single-index regression approach. The primary motivation is to estimate an…

统计方法学 · 统计学 2021-02-02 Hyung Park , Eva Petkova , Thaddeus Tarpey , R. Todd Ogden

We propose a generalized partially linear functional single index risk score model for repeatedly measured outcomes where the index itself is a function of time. We fuse the nonparametric kernel method and regression spline method, and…

统计理论 · 数学 2015-10-15 Fei Jiang , Yanyuan Ma , Yuanjia Wang

The Gaussian graphical model (GGM) incorporates an undirected graph to represent the conditional dependence between variables, with the precision matrix encoding partial correlation between pair of variables given the others. To achieve…

统计方法学 · 统计学 2023-07-03 Yueqi Qian , Xianghong Hu , Can Yang

Sparse regularized regression methods are now widely used in genome-wide association studies (GWAS) to address the multiple testing burden that limits discovery of potentially important predictors. Linear mixed models (LMMs) have become an…

统计方法学 · 统计学 2022-06-27 Julien St-Pierre , Karim Oualkacha , Sahir Rai Bhatnagar

The generalized partially linear additive model (GPLAM) is a flexible and interpretable approach to building predictive models. It combines features in an additive manner, allowing each to have either a linear or nonlinear effect on the…

统计方法学 · 统计学 2018-03-29 Yin Lou , Jacob Bien , Rich Caruana , Johannes Gehrke

Longitudinal binary or count functional data are common in neuroscience, but are often too large to analyze with existing functional regression methods. We propose one-step penalized generalized estimating equations that supports…

统计方法学 · 统计学 2026-03-31 Gabriel Loewinger , Alex W. Levis , Erjia Cui , Francisco Pereira

Single-index models are natural extensions of linear models and circumvent the so-called curse of dimensionality. They are becoming increasingly popular in many scientific fields including biostatistics, medicine, economics and financial…

统计理论 · 数学 2012-11-26 Xia Cui , Wolfgang Karl Härdle , Lixing Zhu

Generalized additive index models (GAIMs) offer a flexible semiparametric framework for capturing complex data relationships, balancing the interpretability of parametric models with the flexibility of nonparametric approaches. However,…

统计方法学 · 统计学 2026-05-29 Ziyu Peng , Linglingzhi Zhu , Yao Xie

The multivariate regression interpretation of the Gaussian chain graph model simultaneously parametrizes (i) the direct effects of $p$ predictors on $q$ outcomes and (ii) the residual partial covariances between pairs of outcomes. We…

统计方法学 · 统计学 2024-03-28 Yunyi Shen , Claudia Solís-Lemus , Sameer K. Deshpande

We consider estimation and inference in a single index regression model with an unknown but smooth link function. In contrast to the standard approach of using kernels or regression splines, we use smoothing splines to estimate the smooth…

统计方法学 · 统计学 2019-05-28 Arun Kumar Kuchibhotla , Rohit Kumar Patra

State-space models are used in a wide range of time series analysis formulations. Kalman filtering and smoothing are work-horse algorithms in these settings. While classic algorithms assume Gaussian errors to simplify estimation, recent…

Covariate adjustment is a widely used technique in randomized clinical trials (RCTs) for improving the efficiency of treatment effect estimators. By adjusting for predictive baseline covariates, variance can be reduced, enhancing…

统计方法学 · 统计学 2025-10-16 Mathias Lerbech Jeppesen , Emilie Højbjerre-Frandsen

Generalized additive models (GAMs) are a well-established statistical tool for modeling complex nonlinear relationships between covariates and a response assumed to have a conditional distribution in the exponential family. In this article,…

统计方法学 · 统计学 2021-03-02 Oswaldo Gressani , Philippe Lambert

There are proposals that extend the classical generalized additive models (GAMs) to accommodate high-dimensional data ($p>>n$) using group sparse regularization. However, the sparse regularization may induce excess shrinkage when estimating…

统计方法学 · 统计学 2022-07-07 Boyi Guo , Byron C. Jaeger , A. K. M. Fazlur Rahman , D. Leann Long , Nengjun Yi

We propose a novel method to model nonlinear regression problems by adapting the principle of penalization to Partial Least Squares (PLS). Starting with a generalized additive model, we expand the additive component of each variable in…

统计理论 · 数学 2010-08-13 Nicole Kraemer , Anne-Laure Boulesteix , Gerhard Tutz

Generalized partially linear single-index models (GPLSIMs) provide a flexible and interpretable semiparametric framework for longitudinal outcomes by combining a low-dimensional parametric component with a nonparametric index component. For…

统计方法学 · 统计学 2026-02-19 Tianni Zhang , Yuyao Wang , Yu Lu , Mengfei Ran
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