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Confocal laser endomicroscopy (CLE) is a novel imaging modality that provides in vivo histological cross-sections of examined tissue. Recently, attempts have been made to develop miniaturized in vivo imaging devices, specifically confocal…

计算机视觉与模式识别 · 计算机科学 2018-06-22 Saeed Izadi , Kathleen P. Moriarty , Ghassan Hamarneh

Purpose: To present a computational procedure for accelerated, calibrationless magnetic resonance image (Cl-MRI) reconstruction that is fast, memory efficient, and scales to high-dimensional imaging. Theory and Methods: Cl-MRI methods can…

图像与视频处理 · 电气工程与系统科学 2021-07-23 Shen Zhao , Lee C. Potter , Rizwan Ahmad

Confocal laser endomicroscopy (CLE), although capable of obtaining images at cellular resolution during surgery of brain tumors in real time, creates as many non-diagnostic as diagnostic images. Non-useful images are often distorted due to…

计算机视觉与模式识别 · 计算机科学 2018-01-09 Mohammadhassan Izadyyazdanabadi , Evgenii Belykh , Nikolay Martirosyan , Jennifer Eschbacher , Peter Nakaji , Yezhou Yang , Mark C. Preul

Confocal laser endomicroscopy (CLE) is an advanced optical fluorescence technology undergoing assessment for applications in brain tumor surgery. Despite its promising potential, interpreting the unfamiliar gray tone images of fluorescent…

Confocal Laser Endomicroscope (CLE) is a novel handheld fluorescence imaging device that has shown promise for rapid intraoperative diagnosis of brain tumor tissue. Currently CLE is capable of image display only and lacks an automatic…

Significance: Confocal laser scanning enables optical sectioning in fiber bundle endomicroscopy but limits the frame rate. To be able to better explore tissue morphology it is useful to stitch sequentially acquired frames into a mosaic.…

光学 · 物理学 2021-07-14 Andrew D. Thrapp , Michael R. Hughes

Confocal Laser Endomicroscopy (CLE), an optical imaging technique allowing non-invasive examination of the mucosa on a (sub)cellular level, has proven to be a valuable diagnostic tool in gastroenterology and shows promising results in…

计算机视觉与模式识别 · 计算机科学 2018-05-07 Maike P. Stoeve , Marc Aubreville , Nicolai Oetter , Christian Knipfer , Helmut Neumann , Florian Stelzle , Andreas Maier

High-resolution real-time intraocular imaging of retina at the cellular level is very challenging due to the vulnerable and confined space within the eyeball as well as the limited availability of appropriate modalities. A probe-based…

Purpose: Probe-based Confocal Laser Endomicroscopy (pCLE) is a recent imaging modality that allows performing in vivo optical biopsies. The design of pCLE hardware, and its reliance on an optical fibre bundle, fundamentally limits the image…

计算机视觉与模式识别 · 计算机科学 2018-04-25 Daniele Ravì , Agnieszka Barbara Szczotka , Dzhoshkun Ismail Shakir , Stephen P Pereira , Tom Vercauteren

Motivated by single-particle cryo-electron microscopy, multi-reference alignment (MRA) models the task of recovering an unknown signal from multiple noisy observations corrupted by random rotations. The standard approach,…

信号处理 · 电气工程与系统科学 2026-01-09 Shay Kreymer , Amnon Balanov , Tamir Bendory

To effectively leverage user-specific data, retrieval augmented generation (RAG) is employed in multimodal large language model (MLLM) applications. However, conventional retrieval approaches often suffer from limited retrieval accuracy.…

计算机视觉与模式识别 · 计算机科学 2026-03-04 Maoliang Li , Ke Li , Yaoyang Liu , Jiayu Chen , Zihao Zheng , Yinjun Wu , Chenchen Liu , Xiang Chen

Despite recent advances, high performance single-shot 3D microscopy remains an elusive task. By introducing designed diffractive optical elements (DOEs), one is capable of converting a microscope into a 3D "kaleidoscope", in which case the…

We study the performance of CLAIRE -- a diffeomorphic multi-node, multi-GPU image-registration algorithm, and software -- in large-scale biomedical imaging applications with billions of voxels. At such resolutions, most existing software…

计算机视觉与模式识别 · 计算机科学 2022-09-20 Naveen Himthani , Malte Brunn , Jae-Youn Kim , Miriam Schulte , Andreas Mang , George Biros

Recent development of lensless imagers has enabled three-dimensional (3D) imaging through a thin piece of optics in close proximity to a camera sensor. A general challenge of wide-field lensless imaging is the high computational complexity…

光学 · 物理学 2021-08-17 Feng Tian , Junjie Hu , Weijian Yang

We extend our previously proposed image reconstruction method, which allows confocal microscopes to capture periodically moving objects at frequencies beyond their frame rates, to three-dimensional and two-dimensional wide-field imaging.…

光学 · 物理学 2026-03-03 Kanta Adachi , Soyoka Hemmi , Nobutomo Nakamura

Confocal laser endomicroscopy (CLE) allow on-the-fly in vivo intraoperative imaging in a discreet field of view, especially for brain tumors, rather than extracting tissue for examination ex vivo with conventional light microscopy.…

Fast, volumetric imaging over large scales has been a long-standing goal in biological microscopy. Scanning techniques such as fluorescence confocal microscopy can acquire 2D images at high resolution and high speed, but extending the…

This paper presents a multilevel framework for inertial and inexact proximal algorithms, that encompasses multilevel versions of classical algorithms such as forward-backward and FISTA. The methods are supported by strong theoretical…

最优化与控制 · 数学 2024-04-03 Guillaume Lauga , Elisa Riccietti , Nelly Pustelnik , Paulo Gonçalves

The surgical removal of head and neck tumors requires safe margins, which are usually confirmed intraoperatively by means of frozen sections. This method is, in itself, an oversampling procedure, which has a relatively low sensitivity…

Large Multimodal Models (LMMs) have made significant strides in visual question-answering for single images. Recent advancements like long-context LMMs have allowed them to ingest larger, or even multiple, images. However, the ability to…

计算机视觉与模式识别 · 计算机科学 2025-03-12 Tsung-Han Wu , Giscard Biamby , Jerome Quenum , Ritwik Gupta , Joseph E. Gonzalez , Trevor Darrell , David M. Chan
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