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Randomized controlled trials are the standard method for estimating causal effects, ensuring sufficient statistical power and confidence through adequate sample sizes. However, achieving such sample sizes is often challenging. This study…

统计方法学 · 统计学 2025-03-28 Keisuke Hanada , Masahiro Kojima

Random-effects meta-analyses are used to combine evidence of treatment effects from multiple studies. Since treatment effects may vary across trials due to differences in study characteristics, heterogeneity in treatment effects between…

统计方法学 · 统计学 2017-07-10 Tim Friede , Christian Röver , Simon Wandel , Beat Neuenschwander

Randomized controlled trials often do not represent the populations where decisions are made, and covariate shift across studies can invalidate standard IPD meta-analysis and transport estimators. We propose a placebo-anchored transport…

机器学习 · 统计学 2026-04-08 Zilong Wang , Ali Abdeen , Turgay Ayer

Methods for estimating heterogeneous treatment effect in observational data have largely focused on continuous or binary outcomes, and have been relatively less vetted with survival outcomes. Using flexible machine learning methods in the…

应用统计 · 统计学 2021-07-09 Liangyuan Hu , Jiayi Ji , Fan Li

Motivated by the Acute Respiratory Distress Syndrome Network (ARDSNetwork) ARDS respiratory management (ARMA) trial, we developed a flexible Bayesian machine learning approach to estimate the average causal effect and heterogeneous causal…

应用统计 · 统计学 2024-10-29 Xinyuan Chen , Michael O. Harhay , Guangyu Tong , Fan Li

While randomized trials may be the gold standard for evaluating the effectiveness of the treatment intervention, in some special circumstances, single-arm clinical trials utilizing external control may be considered. The causal treatment…

统计方法学 · 统计学 2025-05-26 Huan Wang , Fei Wu , Yeh-Fong Chen

T-wave alternans (TWA) is a potential marker for sudden cardiac death, but its reliable analysis is often constrained to noise-free environments, limiting its utility in real-world settings. We explore model-based T-wave estimation to…

医学物理 · 物理学 2025-04-28 Zuzana Koscova , Amit Shah , Ali Bahrami Rad , Qiao Li , Gari D Clifford , Reza Sameni

This paper presents a research devoted to the study of instability phenomena in non-linear model with a constant brake friction coefficient. This paper outlines the stability analysis and a procedure to reduce and simplify the non-linear…

混沌动力学 · 物理学 2012-09-28 Jean-Jacques Sinou , Fabrice Thouverez , Louis Jezequel

The average treatment effect on the treated (ATT) in a staggered-adoption panel is estimated using an intercept-augmented synthetic-control (SCM) estimator. A weighted parallel trends plus an intercept shift, together with mild regularity…

统计方法学 · 统计学 2025-08-08 Michael Guggisberg

We study the estimation of the ATE in randomized controlled trials under a dynamically evolving interference structure. This setting arises in applications such as ride-sharing, where drivers move over time, and social networks, where…

统计理论 · 数学 2025-11-11 Su Jia , Peter Frazier , Nathan Kallus , Christina Lee Yu

In many practical situations, randomly assigning treatments to subjects is uncommon due to feasibility constraints. For example, economic aid programs and merit-based scholarships are often restricted to those meeting specific income or…

统计方法学 · 统计学 2025-04-25 Kevin Christian Wibisono , Debarghya Mukherjee , Moulinath Banerjee , Ya'acov Ritov

Based on the reliability budget and percentile travel time (PTT) concept, a new travel time index named combined mean travel time (CMTT) under stochastic traffic network was proposed. CMTT here was defined as the convex combination of the…

最优化与控制 · 数学 2015-03-12 Wen-Yi Zhang , Wei Guan , Li-Ying Song , Hui-Jun Sun

Network meta-analysis (NMA) is widely used to compare multiple interventions simultaneously by synthesizing direct and indirect evidence. The general fixed or random effects contrast-based NMA model can be applied to different outcomes and…

统计方法学 · 统计学 2026-03-03 Harlan Campbell , Jeroen P. Jansen

While attention-based encoder-decoder (AED) models have been successfully extended to the online variants for streaming automatic speech recognition (ASR), such as monotonic chunkwise attention (MoChA), the models still have a large label…

音频与语音处理 · 电气工程与系统科学 2021-07-16 Hirofumi Inaguma , Tatsuya Kawahara

We address the problem of estimating heterogeneous treatment effects in panel data, adopting the popular Difference-in-Differences (DiD) framework under the conditional parallel trends assumption. We propose a novel doubly robust…

机器学习 · 统计学 2025-04-29 Hui Lan , Haoge Chang , Eleanor Dillon , Vasilis Syrgkanis

Meta-analysis is a statistical method used in evidence synthesis for combining, analyzing and summarizing studies that have the same target endpoint and aims to derive a pooled quantitative estimate using fixed and random effects models or…

统计方法学 · 统计学 2022-04-25 Ivette Raices Cruz , Matthias C. M. Troffaes , Johan Lindström , Ullrika Sahlin

Meta-analysis is a powerful tool for assessing drug safety by combining treatment-related toxicological findings across multiple studies, as clinical trials are typically underpowered for detecting adverse drug effects. However, incomplete…

统计方法学 · 统计学 2024-02-12 Xinyue Qi , Shouhao Zhou , Christine B. Peterson , Yucai Wang , Xinying Fang , Michael L. Wang , Chan Shen

We consider the setting of an aggregate data meta-analysis of a continuous outcome of interest. When the distribution of the outcome is skewed, it is often the case that some primary studies report the sample mean and standard deviation of…

We consider the problem of designing a randomized experiment on a source population to estimate the Average Treatment Effect (ATE) on a target population. We propose a novel approach which explicitly considers the target when designing the…

统计方法学 · 统计学 2021-09-07 My Phan , David Arbour , Drew Dimmery , Anup B. Rao

We propose a framework for testing the homogeneity of conditional average treatment effects (CATEs) across multiple experimental and observational studies. Our approach leverages multiple randomized trials to assess whether treatment…

计量经济学 · 经济学 2026-02-25 Ana Armendariz , Martin Huber
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