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Dense monolayers of living cells display intriguing relaxation dynamics, reminiscent of soft and glassy materials close to the jamming transition, and migrate collectively when space is available, as in wound healing or in cancer invasion.…

We propose a formal framework based on collective coordinates to reduce infinite-dimensional stochastic partial differential equations (SPDEs) with symmetry to a set of finite-dimensional stochastic differential equations which describe the…

斑图形成与孤子 · 物理学 2019-03-26 Madeleine C. Cartwright , Georg A. Gottwald

With the aim of understanding the emergence of collective motion from local interactions of organisms in a "noisy" environment, we study biologically inspired, inherently non-equilibrium models consisting of self-propelled particles. In…

生物物理 · 物理学 2009-10-31 A. Czirok , T. Vicsek

We investigate a set of design principles that link specific features of interparticle interactions to predictable structural and dynamic outcomes in two-dimensional self-assembly, a framework relevant to soft matter and biological…

软凝聚态物质 · 物理学 2026-01-06 Cecilia Bores , Antonio Diaz-Pozuelo , Enrique Lomba

Understanding the causes and effects of spatial aggregation is one of the most fundamental problems in ecology. Aggregation is an emergent phenomenon arising from the interactions between the individuals of the population, able to sense…

种群与进化 · 定量生物学 2015-06-05 Juan A. Bonachela , Miguel A. Munoz , Simon A. Levin

The review is devoted to the theory of collective and it local pinning effects in various disordered non-linear driven systems. Although the emphasis is put on charge and spin density waves and magnetic domain walls, the theory has also…

统计力学 · 物理学 2009-11-10 Serguei Brazovskii , Thomas Nattermann

Internal feedbacks are commonly present in biological populations and can play a crucial role in the emergence of collective behavior. We consider a generalization of Fisher-KPP equation to describe the temporal evolution of the…

适应与自组织系统 · 物理学 2019-07-03 V. Dornelas , E. H. Colombo , C. Anteneodo

The formation of out-of-equilibrium patterns is a characteristic feature of spatially-extended, biodiverse, ecological systems. Intriguing examples are provided by cyclic competition of species, as metaphorically described by the…

种群与进化 · 定量生物学 2008-08-31 Tobias Reichenbach , Mauro Mobilia , Erwin Frey

Dynamics maintaining diversity of cell types in a multi-cellular system are studied in relationship with the plasticity of cellular states. First, we introduce a new theoretical framework, reaction-diffusion system on `chemical species…

适应与自组织系统 · 物理学 2007-05-23 Hiroaki Takagi , Kunihiko Kaneko

The motility of eukaryotic cells is strongly influenced by their environment, with confined cells often developing qualitatively different motility patterns from those migrating on simple two-dimensional substrates. Recent experiments,…

细胞行为 · 定量生物学 2024-12-24 Pedrom Zadeh , Brian A. Camley

In this study, we investigate the phenomenon of collective motion in binary mixtures of self-propelled particles. We consider two particle species, each of which consisting of pointlike objects that propel with a velocity of constant…

软凝聚态物质 · 物理学 2013-11-20 Andreas M. Menzel

In active matter systems, self-propelled particles can self-organize to undergo collective motion, leading to persistent dynamical behavior out of equilibrium. In cells, cytoskeletal filaments and motor proteins self-organize into complex…

软凝聚态物质 · 物理学 2020-05-19 Jeffrey M. Moore , Tyler N. Thompson , Matthew A. Glaser , Meredith D. Betterton

We investigate the nonequilibrium dynamics of active matter using a two-dimensional active Brownian particles model. In these systems, self-propelled particles undergo motility-induced phase separation (MIPS), spontaneously segregating into…

软凝聚态物质 · 物理学 2026-02-26 Toranosuke Umemura , Issei Sakai , Takuma Akimoto

A key question in evolution is how likely a mutant is to take over. This depends on natural selection and on stochastic fluctuations. Population spatial structure can impact mutant fixation probabilities. We introduce a model for structured…

种群与进化 · 定量生物学 2021-11-23 Loïc Marrec , Irene Lamberti , Anne-Florence Bitbol

We consider the rich variety of collective motion patterns emerging when aligning active particles move in the presence of randomly distributed obstacles - representing quenched noise in two dimensions. In order to get insight into the…

软凝聚态物质 · 物理学 2023-02-21 Danial Vahabli , Tamas Vicsek

Bone remodeling is a complex process involving cell-cell interactions, biochemical signaling and mechanical stimuli. Early models of the biological aspects of remodeling were non-spatial and focused on the local dynamics at a fixed location…

种群与进化 · 定量生物学 2016-09-05 Marc D. Ryser , Kevin A. Murgas

An extension of coupled maps is given which allows for the growth of the number of elements, and is inspired by the cell differentiation problem. The growth of elements is made possible first by clustering the phases, and then by…

adap-org · 物理学 2009-10-28 Kunihiko Kaneko

Self-propelled particles can navigate complex environments, including viscous fluid interfaces with curved geometries. In this work, we study the emergent dynamics of a suspension of self-propelled particles confined to a stationary curved…

流体动力学 · 物理学 2026-04-17 Yuzhu Chen , Vishal P. Patil , David Saintillan

We model an enclosed system of bacteria, whose motility-induced phase separation is coupled to slow population dynamics. Without noise, the system shows both static phase separation and a limit cycle, in which a rising global population…

统计力学 · 物理学 2017-11-08 Tobias Grafke , Michael E. Cates , Eric Vanden-Eijnden

The directed migration of cells toward stiffer substrate regions or durotaxis is relevant to tissue development and tumor progression. Here, we introduce a phenomenological model for single cell durotaxis that incorporates both elastic…

软凝聚态物质 · 物理学 2024-12-24 Subhaya Bose , Haiqin Wang , Xinpeng Xu , Arvind Gopinath , Kinjal Dasbiswas