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People with diabetes need insulin delivery to effectively manage their blood glucose levels, especially after meals, because their bodies either do not produce enough insulin or cannot fully utilize it. Accurate insulin delivery starts with…

系统与控制 · 电气工程与系统科学 2024-11-21 Hanyu Zeng , Hui Ji , Pengfei Zhou

Learning high-performance control policies that remain consistent with expert behavior is a fundamental challenge in robotics. Reinforcement learning can discover high-performing strategies but often departs from desirable human behavior,…

机器人学 · 计算机科学 2026-04-06 Siwei Ju , Jan Tauberschmidt , Oleg Arenz , Peter van Vliet , Jan Peters

This study explored healthcare professionals' perspectives on the management of Type 1 Diabetes Mellitus (T1DM) through a two-part questionnaire. The first part examined how clinicians prioritise and apply current clinical guidelines,…

人机交互 · 计算机科学 2026-03-27 Mohammed Basheikh , Rujiravee Kongdee , Hood Thabit , Bijan Parsia , Sarah Clinch , Simon Harper

This paper explores the application of reinforcement learning to optimize the parameters of a Type-1 Takagi-Sugeno fuzzy controller, designed to operate as an artificial pancreas for Type 1 diabetes. The primary challenge in diabetes…

系统与控制 · 电气工程与系统科学 2025-03-11 Omar Mameche , Abdelhadi Abedou , Taqwa Mezaache , Mohamed Tadjine

Background: Accurate week-ahead forecasts of continuous glucose monitoring (CGM) derived metrics could enable proactive diabetes management, but relative performance of modern tabular learning approaches is incompletely defined. Methods: We…

其他定量生物学 · 定量生物学 2026-01-05 Simon Lebech Cichosz , Stine Hangaard , Thomas Kronborg , Peter Vestergaard , Morten Hasselstrøm Jensen

Reinforcement learning (RL) requires skillful definition and remarkable computational efforts to solve optimization and control problems, which could impair its prospect. Introducing human guidance into reinforcement learning is a promising…

机器学习 · 计算机科学 2022-11-30 Jingda Wu , Zhiyu Huang , Wenhui Huang , Chen Lv

In session-based or sequential recommendation, it is important to consider a number of factors like long-term user engagement, multiple types of user-item interactions such as clicks, purchases etc. The current state-of-the-art supervised…

机器学习 · 计算机科学 2020-06-12 Xin Xin , Alexandros Karatzoglou , Ioannis Arapakis , Joemon M. Jose

Safe Reinforcement Learning (RL) aims to find a policy that achieves high rewards while satisfying cost constraints. When learning from scratch, safe RL agents tend to be overly conservative, which impedes exploration and restrains the…

机器人学 · 计算机科学 2023-10-16 Jinning Li , Xinyi Liu , Banghua Zhu , Jiantao Jiao , Masayoshi Tomizuka , Chen Tang , Wei Zhan

Type 1 diabetes is a serious disease in which individuals are unable to regulate their blood glucose levels, leading to various medical complications. Artificial pancreas (AP) systems have been developed as a solution for type 1 diabetic…

信号处理 · 电气工程与系统科学 2023-05-18 Ke Ma , Hongkai Chen , Shan Lin

Reinforcement Learning (RL) is increasingly used in autonomous driving (AD) and shows clear advantages. However, most RL-based AD methods overlook policy structure design. An RL policy that only outputs short-timescale vehicle control…

机器人学 · 计算机科学 2025-11-25 Guizhe Jin , Zhuoren Li , Bo Leng , Ran Yu , Lu Xiong , Chen Sun

Progress in Type 1 Diabetes (T1D) algorithm development is limited by the fragmentation and lack of standardization across existing T1D management datasets. Current datasets differ substantially in structure and are time-consuming to access…

机器学习 · 计算机科学 2026-04-23 Miriam K. Wolff , Peter Calhoun , Eleonora Maria Aiello , Yao Qin , Sam F. Royston

Managing Type 1 diabetes (T1D) aims to optimize glucose levels within the target range while minimizing hyperglycemia and hypoglycemia. Exercise presents additional challenges due to complex effects on glucose dynamics. Despite advancements…

定量方法 · 定量生物学 2025-04-03 Ahtsham Zafar , Abiodun Solanke , Dana M. Lewis , Arsalan Shahid

With continuous glucose monitoring (CGM), data-driven models on blood glucose prediction have been shown to be effective in related work. However, such (CGM) systems are not always available, e.g., for a patient at home. In this work, we…

计算机与社会 · 计算机科学 2024-04-10 Tu Nguyen , Markus Rokicki

Objective: Create precise, structured, data-backed guidelines for type 2 diabetes treatment progression, suitable for clinical adoption. Research Design and Methods: Our training cohort was composed of patient (with type 2 diabetes) visits…

人工智能 · 计算机科学 2025-04-18 Dewang Kumar Agarwal , Dimitris J. Bertsimas

Objective: The artificial pancreas (AP) has shown promising potential in achieving closed-loop glucose control for individuals with type 1 diabetes mellitus (T1DM). However, designing an effective control policy for the AP remains…

人工智能 · 计算机科学 2023-07-17 Wenzhou Lv , Tianyu Wu , Luolin Xiong , Liang Wu , Jian Zhou , Yang Tang , Feng Qian

In offline reinforcement learning (RL), an RL agent learns to solve a task using only a fixed dataset of previously collected data. While offline RL has been successful in learning real-world robot control policies, it typically requires…

机器学习 · 计算机科学 2024-08-09 Nicholas E. Corrado , Yuxiao Qu , John U. Balis , Adam Labiosa , Josiah P. Hanna

Clinical time-series forecasting is increasingly studied for decision support, yet standard aggregate metrics can obscure whether a model is actually useful for the task it is meant to serve. In safety-critical settings, low average error…

机器学习 · 计算机科学 2026-05-04 Alireza Namazi , Heman Shakeri

Significant advancements in type 1 diabetes treatment have been made in the development of state-of-the-art Artificial Pancreas Systems (APS). However, lapses currently exist in the timely treatment of unsafe blood glucose (BG) levels,…

机器学习 · 计算机科学 2023-03-20 Chloe Smith , Maxfield Kouzel , Xugui Zhou , Homa Alemzadeh

Standard reinforcement learning (RL) aims to find an optimal policy that identifies the best action for each state. However, in healthcare settings, many actions may be near-equivalent with respect to the reward (e.g., survival). We…

机器学习 · 计算机科学 2020-07-27 Shengpu Tang , Aditya Modi , Michael W. Sjoding , Jenna Wiens

Large clinical evidence acknowledges the crucial role played by physical activity in delaying the progression of type-2 diabetes. However, the literature lacks control approaches that leverage exercise for type-2 diabetes control and more…

系统与控制 · 电气工程与系统科学 2025-01-23 Pierluigi Francesco De Paola , Alessandro Borri , Fabrizio Dabbene , Pasquale Palumbo , Alessia Paglialonga