相关论文: Analyzing Vaccine Manufacturing Supply Chain Disru…

COVID-19 resulted in some of the largest supply chain disruptions in recent history. To mitigate the impact of future disruptions, we propose an integrated hybrid simulation framework to couple nonstationary demand signals from an event…

The COVID19 pandemic has highlighted the lack of resilience in supply chains, as global networks fail from disruptions at single nodes and connections. Through an overview of the existing vaccine and pharmaceutical supply chain publications…

Vaccines play a crucial role in the prevention and control of infectious diseases. However, the vaccine supply chain faces numerous challenges that hinder its efficiency. To address these challenges and enhance public health outcomes, many…

Timely and effective decision-making is critical during epidemics to reduce preventable infections and deaths. This demands integrated models that jointly capture disease dynamics, vaccine distribution, regional disparities, and behavioral…

Recent pandemics have highlighted vulnerabilities in our global economic systems, especially supply chains. Possible future pandemic raises a dilemma for businesses owners between short-term profitability and long-term supply chain…

This research investigates a multi-product, multi-echelon, and multi-period vaccine supply chain network model under uncertainty and quality inspection errors. The objective function seeks optimizing the total cost of the supply chain.…

Purpose: Only few companies were able to produce vaccine again COVID-19. Thus, one producer supplied it to many countries. The distribution was not effective. Some countries overstocked the vaccine while other countries were not able to buy…

In this study, a vaccine supply chain model is developed considering the humanitarian aspects under uncertain conditions in Iran. There are three main components to supply the required vaccines for vaccination centers that can be designed…

The Covid-19 pandemic drastically emphasized the fragility of national and international supply networks (SNs),leading to significant supply shortages of essential goods for people, such as food and medical equipment. Severe disruptions…

Drug shortages occur frequently and are often caused by supply chain disruptions. For improvements to occur, it is necessary to be able to estimate the vulnerability of pharmaceutical supply chains. In this work, we present the first model…

During various stages of the COVID-19 pandemic, countries implemented diverse vaccine management approaches, influenced by variations in infrastructure and socio-economic conditions. This article provides a comprehensive overview of…

The COVID-19 pandemic highlighted significant challenges in the allocation of vital healthcare resources. Existing epidemiological models, specifically compartmental models, aimed to predict the spread of the COVID-19 virus and its impact…

Modern supply chains are increasingly exposed to disruptions from geopolitical events, demand shocks, trade restrictions, to natural disasters. While many of these disruptions originate deep in the supply network, most companies still lack…

Operational disruptions can significantly impact companies performance. Ford, with its 37 plants globally, uses 17 billion parts annually to manufacture six million cars and trucks. With up to ten tiers of suppliers between the company and…

Millions of young people are not immunized in low- and middle-income (LMI) countries because of low vaccine availability resulting from inefficiencies in cold supply chains. We create supply chain network design and distribution models to…

Clinical trials of a vaccine during an epidemic face particular challenges, such as the pressure to identify an effective vaccine quickly to control the epidemic, and the effect that time-space-varying infection incidence has on the power…

In this paper, we present a decision support framework for optimizing multiple aspects of vaccine distribution across a multitier cold chain network. We propose two multi-period optimization formulations within this framework: first to…

The COVID-19 pandemic showed that stocking and procuring vaccines are different from the inventory holding problems of production. The safety of the supply is more important than cost minimization. The Hungarian inventory model is applied…

Disasters and disruptions such as the COVID-19 pandemic can significantly interrupt supply chains and industries. To control these disruptions, decision-makers must focus on supply chain resiliency. This paper proposes a multi-stage,…

Motivated by the COVID-19 pandemic, this paper explores the supply chain viability of medical equipment, an industry whose supply chain was put under a crucial test during the pandemic. This paper includes an empirical network-level…