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Endoscopic imaging is commonly used to diagnose Ulcerative Colitis (UC) and classify its severity. It has been shown that deep learning based methods are effective in automated analysis of these images and can potentially be used to aid…

图像与视频处理 · 电气工程与系统科学 2023-11-13 Ümit Mert Çağlar , Alperen İnci , Oğuz Hanoğlu , Görkem Polat , Alptekin Temizel

Estimating how a treatment affects units individually, known as heterogeneous treatment effect (HTE) estimation, is an essential part of decision-making and policy implementation. The accumulation of large amounts of data in many domains,…

机器学习 · 计算机科学 2022-06-28 Christopher Tran , Elena Zheleva

Machine Learning applications have brought new insights into a secondary analysis of medical data. Machine Learning helps to develop new drugs, define populations susceptible to certain illnesses, identify predictors of many common…

机器学习 · 计算机科学 2020-12-29 YuanZheng Hu , Marina Sokolova

Estimating treatment effects (TE) from observational data is a critical yet complex task in many fields, from healthcare and economics to public policy. While recent advances in machine learning and causal inference have produced powerful…

Understanding causal heterogeneity is essential for scientific discovery in domains such as biology and medicine. However, existing methods lack causal awareness, with insufficient modeling of heterogeneity, confounding, and observational…

机器学习 · 计算机科学 2025-10-29 Wenrui Li , Qinghao Zhang , Xiaowo Wang

The importance of clinical variables in the prognosis of the disease is explained using statistical correlation or machine learning (ML). However, the predictive importance of these variables may not represent their causal relationships…

机器学习 · 统计学 2025-06-04 Yina Hou , Shourav B. Rabbani , Liang Hong , Norou Diawara , Manar D. Samad

Inflammatory bowel disease (IBD), in particular ulcerative colitis (UC), is graded by endoscopists and this assessment is the basis for risk stratification and therapy monitoring. Presently, endoscopic characterisation is largely operator…

计算机视觉与模式识别 · 计算机科学 2022-07-13 Ziang Xu , Sharib Ali , Soumya Gupta , Simon Leedham , James E East , Jens Rittscher

Understanding treatment effect heterogeneity is vital to many scientific fields because the same treatment may affect different individuals differently. Quantile regression provides a natural framework for modeling such heterogeneity. We…

统计方法学 · 统计学 2023-07-12 Alexander Giessing , Jingshen Wang

Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by relapsing inflammation of the large intestine. The severity of UC is often represented by the Mayo Endoscopic Subscore (MES) which quantifies mucosal disease…

图像与视频处理 · 电气工程与系统科学 2021-10-01 Evan Schwab , Gabriela Oana Cula , Kristopher Standish , Stephen S. F. Yip , Aleksandar Stojmirovic , Louis Ghanem , Christel Chehoud

Estimating personalized effects of treatments is a complex, yet pervasive problem. To tackle it, recent developments in the machine learning (ML) literature on heterogeneous treatment effect estimation gave rise to many sophisticated, but…

机器学习 · 计算机科学 2022-06-17 Jonathan Crabbé , Alicia Curth , Ioana Bica , Mihaela van der Schaar

Machine learning has shown much promise in helping improve the quality of medical, legal, and financial decision-making. In these applications, machine learning models must satisfy two important criteria: (i) they must be causal, since the…

机器学习 · 计算机科学 2021-10-12 Carolyn Kim , Osbert Bastani

In healthcare, predictive models increasingly inform patient-level decisions, yet little attention is paid to the variability in individual risk estimates and its impact on treatment decisions. For overparameterized models, now standard in…

机器学习 · 计算机科学 2026-04-16 Elizabeth W. Miller , Jeffrey D. Blume

Kernel methods are widely used in causal inference for tasks such as treatment effect estimation, policy evaluation, and policy learning. The bootstrap is a standard tool for uncertainty quantification because of its broad applicability. As…

统计方法学 · 统计学 2026-03-17 Matthew Kosko , Falco J , Bargagli-Stoffi , Lin Wang , Michele Santacatterina

Patient stratification identifying clinically meaningful subgroups is essential for advancing personalized medicine through improved diagnostics and treatment strategies. Electronic health records (EHRs), particularly those from intensive…

机器学习 · 计算机科学 2025-06-09 Dimitrios Proios , Alban Bornet , Anthony Yazdani , Jose F Rodrigues , Douglas Teodoro

Predicting whether a treatment leads to meaningful improvement is a central challenge in personalized medicine, particularly when disease progression manifests as subtle visual changes over time. While data-driven deep learning (DL) offers…

图像与视频处理 · 电气工程与系统科学 2025-11-21 Jana Armouti , Nikhil Madaan , Rohan Panda , Tom Fox , Laura Hutchins , Amita Krishnan , Ricardo Rodriguez , Bennett DeBoisblanc , Deva Ramanan , John Galeotti , Gautam Gare

The use of machine learning to guide clinical decision making has the potential to worsen existing health disparities. Several recent works frame the problem as that of algorithmic fairness, a framework that has attracted considerable…

机器学习 · 统计学 2021-06-16 Stephen R. Pfohl , Agata Foryciarz , Nigam H. Shah

With the rise of the digital economy and an explosion of available information about consumers, effective personalization of goods and services has become a core business focus for companies to improve revenues and maintain a competitive…

机器学习 · 计算机科学 2022-11-04 Zhaonan Qu , Isabella Qian , Zhengyuan Zhou

Infrastructure deterioration poses significant challenges for asset management, yet existing approaches rely on population-averaged models that overlook equipment-specific heterogeneity. We present a novel framework that combines Bayesian…

应用统计 · 统计学 2026-05-21 Takato Yasuno

With the advent of massive data sets much of the computational science and engineering community has moved toward data-intensive approaches in regression and classification. However, these present significant challenges due to increasing…

统计计算 · 统计学 2024-04-25 Julio E. Castrillon-Candas

The preclinical stage of many neurodegenerative diseases can span decades before symptoms become apparent. Understanding the sequence of preclinical biomarker changes provides a critical opportunity for early diagnosis and effective…

统计方法学 · 统计学 2024-06-11 Yizhen Xu , Scott Zeger , Zheyu Wang