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Objective: To analyze the frequency and co-occurrence of dermoscopic patterns in BCC lesions and their relationship with histopathologic subtypes, using statistical analysis and Information Theory tools such as entropy, conditional entropy,…

Accurate modeling of cognitive decline in Alzheimer's disease is essential for early stratification and personalized management. While tabular predictors provide robust markers of global risk, their ability to capture subtle brain changes…

计算机视觉与模式识别 · 计算机科学 2025-11-19 Nathaniel Putera , Daniel Vilet Rodríguez , Noah Videcrantz , Julia Machnio , Mostafa Mehdipour Ghazi

In recent years, there has been increasing interest in developing models and tools to address the complex patterns of connectivity found in brain tissue. Specifically, this is due to a need to understand how emergent properties emerge from…

神经元与认知 · 定量生物学 2022-04-15 Sean Knight , Navjot Gadda

Intracranial hemorrhage (ICH) refers to the leakage or accumulation of blood within the skull, which occurs due to the rupture of blood vessels in or around the brain. If this condition is not diagnosed in a timely manner and appropriately…

计算机视觉与模式识别 · 计算机科学 2026-02-10 Mehdi Hosseini Chagahi , Niloufar Delfan , Behzad Moshiri , Md. Jalil Piran , Jaber Hatam Parikhan

We present a mathematical model that describes how tumour heterogeneity evolves in a tissue slice that is oxygenated by a single blood vessel. Phenotype is identified with the stemness level of a cell, $s$, that determines its proliferative…

细胞行为 · 定量生物学 2023-11-14 Giulia L. Celora , Helen M. Byrne , P. G. Kevrekidis

Understanding the structure of the brain, and how it changes with time and disease, is a core goal of structural neuroimaging. Contemporary approaches to structural brain analysis are dominated by voxel-wise, mass-univariate methods such as…

代数拓扑 · 数学 2026-04-28 Donato Quiccione , Mariam Pirashvili , Nathan Broomhead , Sean J. Fallon

Objective: The Mapper algorithm is a qualitative method in topological data analysis that constructs graphs from point clouds by combining dimensionality reduction and clustering techniques. The aim of this study is to apply Mapper,…

Objective: To develop a fast image reconstruction method for stroke monitoring with electrical impedance tomography with image quality comparable to computationally expensive nonlinear model-based methods. Methods: A post-processing…

图像与视频处理 · 电气工程与系统科学 2024-12-12 J. Toivanen , V. Kolehmainen , A. Paldanius , A. Hänninen , A. Hauptmann , S. J. Hamilton

While generative models have shown promise in pediatric sleep analysis, the latent structure of their multimodal embeddings remains poorly understood. This work investigates session-wide diagnostic information contained in the sequences of…

机器学习 · 计算机科学 2026-05-15 Scott Ye , Harlin Lee

Phenotyping is the process of distinguishing groups of patients to identify different types of disease progression. A recent trend employs low-rank matrix and tensor factorization methods for their capability of dealing with multi-modal,…

机器学习 · 计算机科学 2025-06-26 Cristian Minoccheri , Sophia Tesic , Kayvan Najarian , Ryan Stidham

The accurate understanding of ischemic stroke lesions is critical for efficient therapy and prognosis of stroke patients. Magnetic resonance imaging (MRI) is sensitive to acute ischemic stroke and is a common diagnostic method for stroke.…

计算机视觉与模式识别 · 计算机科学 2025-11-11 R. P. Chowdhury , T. Rahman

In this study, we propose the use of persistent homology -- specifically Betti curves for brain age prediction and for distinguishing between healthy and pathological aging. The proposed framework is applied to 100 structural MRI scans from…

神经元与认知 · 定量生物学 2025-11-11 Debanjali Bhattacharya , Neelam Sinha

Learning how to estimate a connectional brain template(CBT) from a population of brain multigraphs, where each graph (e.g., functional) quantifies a particular relationship between pairs of brain regions of interest (ROIs), allows to pin…

机器学习 · 计算机科学 2021-10-08 Oytun Demirbilek , Islem Rekik

Accurate brain tumor diagnosis relies on the assessment of multiple Magnetic Resonance Imaging (MRI) sequences. However, in clinical practice, the acquisition of certain sequences may be affected by factors like motion artifacts or contrast…

图像与视频处理 · 电气工程与系统科学 2025-05-30 Moinak Bhattacharya , Saumya Gupta , Annie Singh , Chao Chen , Gagandeep Singh , Prateek Prasanna

Myocardial Infarction (MI) has the highest mortality of all cardiovascular diseases (CVDs). Detection of MI and information regarding its occurrence-time in particular, would enable timely interventions that may improve patient outcomes,…

信号处理 · 电气工程与系统科学 2021-04-06 Girmaw Abebe Tadesse , Hamza Javed , Yong Liu , Jin Liu , Jiyan Chen , Komminist Weldemariam , Tingting Zhu

In this paper, we demonstrate the feasibility and performance of deep residual neural networks for volumetric segmentation of irreversibly damaged brain tissue lesions on T1-weighted MRI scans for chronic stroke patients. A total of 239…

图像与视频处理 · 电气工程与系统科学 2019-11-27 Naofumi Tomita , Steven Jiang , Matthew E. Maeder , Saeed Hassanpour

Volume change measures derived from longitudinal MRI (e.g. hippocampal atrophy) are a well-studied biomarker of disease progression in Alzheimer's Disease (AD) and are used in clinical trials to track the therapeutic efficacy of…

Brain stroke is a leading cause of mortality and long-term disability worldwide, underscoring the need for precise and rapid prediction techniques. Computed Tomography (CT) scan is considered one of the most effective methods for diagnosing…

Clinical outcome prediction plays an important role in stroke patient management. From a machine learning point-of-view, one of the main challenges is dealing with heterogeneous data at patient admission, i.e. the image data which are…

图像与视频处理 · 电气工程与系统科学 2022-05-12 Nima Hatami , Tae-Hee Cho , Laura Mechtouff , Omer Faruk Eker , David Rousseau , Carole Frindel

Visual summarization of clinical data collected on patients contained within the electronic health record (EHR) may enable precise and rapid triage at the time of patient presentation to an emergency department (ED). The triage process is…

人机交互 · 计算机科学 2019-07-26 Nathan C. Hurley , Adrian D. Haimovich , R. Andrew Taylor , Bobak J. Mortazavi