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Resting-state functional MRI (rs-fMRI) scans hold the potential to serve as a diagnostic or prognostic tool for a wide variety of conditions, such as autism, Alzheimer's disease, and stroke. While a growing number of studies have…

计算机视觉与模式识别 · 计算机科学 2018-06-14 Meenakshi Khosla , Keith Jamison , Amy Kuceyeski , Mert Sabuncu

Parkinson's disease is a neurodegenerative disorder that can be very tricky to diagnose and treat. Such early symptoms can include tremors, wheezy breathing, and changes in voice quality as critical indicators of neural damage. Notably,…

声音 · 计算机科学 2025-11-20 Abishek Karthik , Pandiyaraju V , Dominic Savio M , Rohit Swaminathan S

Multi-sequence of cardiac magnetic resonance (CMR) images can provide complementary information for myocardial pathology (scar and edema). However, it is still challenging to fuse these underlying information for pathology segmentation…

图像与视频处理 · 电气工程与系统科学 2020-08-14 Zhen Zhang , Chenyu Liu , Wangbin Ding , Sihan Wang , Chenhao Pei , Mingjing Yang , Liqin Huang

Early diagnosis, playing an important role in preventing progress and treating the Alzheimer's disease (AD), is based on classification of features extracted from brain images. The features have to accurately capture main AD-related…

机器学习 · 计算机科学 2016-07-05 Ehsan Hosseini-Asl , Georgy Gimel'farb , Ayman El-Baz

Early and accurate identification of parkinsonian syndromes (PS) involving presynaptic degeneration from non-degenerative variants such as Scans Without Evidence of Dopaminergic Deficit (SWEDD) and tremor disorders, is important for…

应用统计 · 统计学 2017-03-07 R. Prashanth , Sumantra Dutta Roy , Pravat K. Mandal , Shantanu Ghosh

Early and accurate detection of Parkinson's disease (PD) is a crucial diagnostic challenge carrying immense clinical significance, for effective treatment regimens and patient management. For instance, a group of subjects termed SWEDD who…

图像与视频处理 · 电气工程与系统科学 2025-06-24 R. Prashanth

It is essential to understand the complex structure of the human brain to develop new treatment approaches for neurodegenerative disorders (NDDs). This review paper comprehensively discusses the challenges associated with modelling the…

神经元与认知 · 定量生物学 2024-11-01 Hina Shaheen , Roderick Melnik

Subject: In this article, convolutional networks of one, two, and three dimensions are compared with respect to their ability to distinguish between the drawing tests produced by Parkinson's disease patients and healthy control subjects.…

Brain-related diseases are more sensitive than other diseases due to several factors, including the complexity of surgical procedures, high costs, and other challenges. Alzheimer's disease is a common brain disorder that causes memory loss…

图像与视频处理 · 电气工程与系统科学 2024-03-11 Maleka Khatun , Md Manowarul Islam , Habibur Rahman Rifat , Md. Shamim Bin Shahid , Md. Alamin Talukder , Md Ashraf Uddin

Parkinson's disease (PD) is a slowly progressing neurodegenerative disease with early manifestation of motor signs. Recently, there has been a growing interest in developing automatic tools that can assess motor function in PD patients.…

信息检索 · 计算机科学 2018-05-04 Liron Allerhand , Brit Youngmann , Elad Yom-Tov , David Arkadir

Parkinson's disease (PD) is a progressive neurodegenerative disorder that results in a variety of motor dysfunction symptoms, including tremors, bradykinesia, rigidity and postural instability. The diagnosis of PD mainly relies on clinical…

计算机视觉与模式识别 · 计算机科学 2022-07-15 Haozheng Zhang , Edmond S. L. Ho , Xiatian Zhang , Hubert P. H. Shum

Current diagnosis and prognosis for Parkinson's disease (PD) face formidable challenges due to the heterogeneous nature of the disease course, including that (i) the impairment severity varies hugely between patients, (ii) whether a symptom…

应用统计 · 统计学 2024-10-03 Kai Kang , Yuqi Gu

Parkinson's Disease (PD) is one of the most common types of neurological diseases caused by progressive degeneration of dopamin- ergic neurons in the brain. Even though there is no fixed cure for this neurodegenerative disease, earlier…

计算机视觉与模式识别 · 计算机科学 2018-06-21 Sara Soltaninejad , Irene Cheng , Anup Basu

In this paper, we propose a novel deep learning method based on a new Hybrid ConvNet-Transformer architecture to detect and stage Parkinson's disease (PD) from gait data. We adopt a two-step approach by dividing the problem into two…

计算机视觉与模式识别 · 计算机科学 2023-10-27 Safwen Naimi , Wassim Bouachir , Guillaume-Alexandre Bilodeau

In heterogeneous disorders like Parkinson's disease (PD), differentiating the affected population into subgroups plays a key role in future research. Discovering subgroups can lead to improved treatments through more powerful enrichment of…

统计方法学 · 统计学 2023-08-08 Elliot Burghardt , Daniel Sewell , Joseph Cavanaugh

Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects cognitive functions such as memory, thinking, and behavior. In this disease, there is a critical phase, mild cognitive impairment, that is really…

信号处理 · 电气工程与系统科学 2024-04-02 Arezoo Borji , Taha-Hossein Hejazi , Abbas Seifi

Alzheimer's disease (AD) is the most prevalent form of dementia, and its early diagnosis is essential for slowing disease progression. Recent studies on multimodal neuroimaging fusion using MRI and PET have achieved promising results by…

计算机视觉与模式识别 · 计算机科学 2025-11-05 Delin Ma , Menghui Zhou , Jun Qi , Yun Yang , Po Yang

Despite the promising performance of state of the art approaches for Parkinsons Disease (PD) detection, these approaches often analyze individual speech segments in isolation, which can lead to suboptimal results. Dysarthric cues that…

机器学习 · 计算机科学 2024-09-17 Shakeel A. Sheikh , Yacouba Kaloga , Md Sahidullah , Ina Kodrasi

We propose a novel optimization framework to predict clinical severity from resting state fMRI (rs-fMRI) data. Our model consists of two coupled terms. The first term decomposes the correlation matrices into a sparse set of representative…

神经元与认知 · 定量生物学 2024-11-25 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart H. Mostofsky , Archana Venkataraman

Parkinson's Disease (PD) is a progressive neurodegenerative disorder that significantly impacts both motor and non-motor functions, including speech. Early and accurate recognition of PD through speech analysis can greatly enhance patient…

数值分析 · 数学 2024-07-24 Niloofar Fadavi , Nazanin Fadavi