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Fully supervised deep models have shown promising performance for many medical segmentation tasks. Still, the deployment of these tools in clinics is limited by the very timeconsuming collection of manually expert-annotated data. Moreover,…

图像与视频处理 · 电气工程与系统科学 2024-11-06 Robin Trombetta , Olivier Rouvière , Carole Lartizien

Esophageal cancer is a major cause of cancer-related mortality internationally, with high recurrence rates and poor survival even among patients treated with curative-intent surgery. Investigating relevant prognostic factors and predicting…

Cancer is a highly heterogeneous condition that can occur almost anywhere in the human body. 18F-fluorodeoxyglucose is an imaging modality commonly used to detect cancer due to its high sensitivity and clear visualisation of the pattern of…

图像与视频处理 · 电气工程与系统科学 2023-04-17 Ashay Patel , Petru-Danial Tudiosu , Walter H. L. Pinaya , Gary Cook , Vicky Goh , Sebastien Ourselin , M. Jorge Cardoso

A prevalent feature of high-dimensional data is the dependence among covariates, and model selection is known to be challenging when covariates are highly correlated. To perform model selection for the high-dimensional Cox proportional…

统计方法学 · 统计学 2022-10-04 Pierre Bayle , Jianqing Fan

In this paper, we make an experimental comparison of semi-parametric (Cox proportional hazards model, Aalen's additive regression model), parametric (Weibull AFT model), and machine learning models (Random Survival Forest, Gradient Boosting…

机器学习 · 计算机科学 2020-03-20 Camila Fernandez , Chung Shue Chen , Pierre Gaillard , Alonso Silva

In the context of the global coronavirus pandemic, different deep learning solutions for infected subject detection using chest X-ray images have been proposed. However, deep learning models usually need large labelled datasets to be…

计算机视觉与模式识别 · 计算机科学 2021-09-03 Saul Calderon-Ramirez , Shengxiang Yang , David Elizondo , Armaghan Moemeni

Early cancer detection is crucial for prognosis, but many cancer types lack large labelled datasets required for developing deep learning models. This paper investigates self-supervised learning (SSL) as an alternative to the standard…

图像与视频处理 · 电气工程与系统科学 2024-11-27 Hamish Haggerty , Rohitash Chandra

Deep learning (DL) has proven highly effective for ultrasound-based computer-aided diagnosis (CAD) of breast cancers. In an automaticCAD system, lesion detection is critical for the following diagnosis. However, existing DL-based methods…

图像与视频处理 · 电气工程与系统科学 2023-06-13 Jian Wang , Liang Qiao , Shichong Zhou , Jin Zhou , Jun Wang , Juncheng Li , Shihui Ying , Cai Chang , Jun Shi

We study inference for censored survival data where some covariates are distorted by some unknown functions of an observable confounding variable in a multiplicative form. Example of this kind of data in medical studies is the common…

统计方法学 · 统计学 2020-06-03 Yanyan Liu , Yuanshan Wu , Jing Zhang , Haibo Zhou

In this study, we address the challenge of survival analysis within heterogeneous patient populations, where traditional reliance on a single regression model such as the Cox proportional hazards (Cox PH) model often falls short.…

统计方法学 · 统计学 2025-04-15 Ahmad Talafha

Identification of biomarkers is an emerging area in Oncology. In this article, we develop an efficient statistical procedure for classification of protein markers according to their effect on cancer progression. A high-dimensional…

应用统计 · 统计学 2021-01-08 Souvik Banerjee , Gajendra K. Vishwakarma , Atanu Bhattacharjee

Time-to-event data is widespread across the life sciences and engineering, but it is typically encountered together with censoring, which complicates the application of standard machine learning methods. Deep Cox models have emerged as a…

机器学习 · 统计学 2026-05-19 Anchit Jain , Kevin Zhang , Stephen Bates

Segmentation of head and neck (H\&N) tumours and prediction of patient outcome are crucial for patient's disease diagnosis and treatment monitoring. Current developments of robust deep learning models are hindered by the lack of large…

图像与视频处理 · 电气工程与系统科学 2021-11-09 Emmanuelle Bourigault , Daniel R. McGowan , Abolfazl Mehranian , Bartłomiej W. Papież

Deep learning has achieved unprecedented success in various object detection tasks with huge amounts of labeled data. However, obtaining large-scale annotations for medical images is extremely challenging due to the high demand of labour…

图像与视频处理 · 电气工程与系统科学 2022-03-21 Zhizhong Chai , Luyang Luo , Huangjing Lin , Hao Chen , Anjia Han , Pheng-Ann Heng

The time-consuming task of manual segmentation challenges routine systematic quantification of disease burden. Convolutional neural networks (CNNs) hold significant promise to reliably identify locations and boundaries of tumors from PET…

Targeted Radionuclide Therapy (TRT) is a modern strategy in radiation oncology that aims to administer a potent radiation dose specifically to cancer cells using cancer-targeting radiopharmaceuticals. Accurate radiation dose estimation…

医学物理 · 物理学 2025-09-15 Jing Zhang , Alexandre Bousse , Chi-Hieu Pham , Kuangyu Shi , Julien Bert

This study presents a comparative methodological analysis of six machine learning models for survival analysis (MLSA). Using data from nearly 45,000 colorectal cancer patients in the Hospital-Based Cancer Registries of S\~ao Paulo, we…

An important goal in cancer research is the survival prognosis of a patient based on a minimal panel of genomic and molecular markers such as genes or proteins. Purely data-driven models without any biological knowledge can produce…

统计方法学 · 统计学 2025-10-02 Tobias Østmo Hermansen , Manuela Zucknick , Zhi Zhao

Deep learning-based diagnostic performance increases with more annotated data, but large-scale manual annotations are expensive and labour-intensive. Experts evaluate diagnostic images during clinical routine, and write their findings in…

图像与视频处理 · 电气工程与系统科学 2024-07-01 Joeran S. Bosma , Anindo Saha , Matin Hosseinzadeh , Ilse Slootweg , Maarten de Rooij , Henkjan Huisman

Survival analysis is a crucial semi-supervised task in machine learning with numerous real-world applications, particularly in healthcare. Currently, the most common approach to survival analysis is based on Cox's partial likelihood, which…

机器学习 · 计算机科学 2023-04-27 Andre Vauvelle , Benjamin Wild , Aylin Cakiroglu , Roland Eils , Spiros Denaxas