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We have gained access to vast amounts of multi-omics data thanks to Next Generation Sequencing. However, it is challenging to analyse this data due to its high dimensionality and much of it not being annotated. Lack of annotated data is a…

机器学习 · 计算机科学 2022-10-04 Sayed Hashim , Karthik Nandakumar , Mohammad Yaqub

In this manuscript we analyze a data set containing information on children with Hodgkin Lymphoma (HL) enrolled on a clinical trial. Treatments received and survival status were collected together with other covariates such as demographics…

定量方法 · 定量生物学 2021-03-29 Cédric Beaulac , Jeffrey S. Rosenthal , Qinglin Pei , Debra Friedman , Suzanne Wolden , David Hodgson

Traditional survival models such as the Cox proportional hazards model are typically based on scalar or categorical clinical features. With the advent of increasingly large image datasets, it has become feasible to incorporate quantitative…

计算机视觉与模式识别 · 计算机科学 2020-01-09 Christoph Haarburger , Philippe Weitz , Oliver Rippel , Dorit Merhof

Wide heterogeneity exists in cancer patients' survival, ranging from a few months to several decades. To accurately predict clinical outcomes, it is vital to build an accurate predictive model that relates patients' molecular profiles with…

机器学习 · 统计学 2023-10-12 Yaohua Rong , Sihai Dave Zhao , Xia Zheng , Yi Li

Prognostic task is of great importance as it closely related to the survival analysis of patients, the optimization of treatment plans and the allocation of resources. The existing prognostic models have shown promising results on specific…

图像与视频处理 · 电气工程与系统科学 2025-01-14 Binyu Zhang , Shichao Li , Junpeng Jian , Zhu Meng , Limei Guo , Zhicheng Zhao

Most existing few-shot learning (FSL) methods require a large amount of labeled data in meta-training, which is a major limit. To reduce the requirement of labels, a semi-supervised meta-training (SSMT) setting has been proposed for FSL,…

计算机视觉与模式识别 · 计算机科学 2025-05-20 Xingping Dong , Tianran Ouyang , Shengcai Liao , Bo Du , Ling Shao

Prediction of Overall Survival (OS) of brain cancer patients from multi-modal MRI is a challenging field of research. Most of the existing literature on survival prediction is based on Radiomic features, which does not consider either…

定量方法 · 定量生物学 2021-09-08 Subhashis Banerjee , Sushmita Mitra , Lawrence O. Hall

Multimodal machine learning integrating histopathology and molecular data shows promise for cancer prognostication. We systematically reviewed studies combining whole slide images (WSIs) and high-throughput omics to predict overall…

定量方法 · 定量生物学 2025-07-30 Charlotte Jennings , Andrew Broad , Lucy Godson , Emily Clarke , David Westhead , Darren Treanor

Semi-supervised learning (SSL) leverages both labeled and unlabeled data for training models when the labeled data is limited and the unlabeled data is vast. Frequently, the unlabeled data is more widely available than the labeled data,…

图像与视频处理 · 电气工程与系统科学 2022-11-07 Isaac Benavides-Mata , Saul Calderon-Ramirez

Morphological attributes from histopathological images and molecular profiles from genomic data are important information to drive diagnosis, prognosis, and therapy of cancers. By integrating these heterogeneous but complementary data, many…

机器学习 · 计算机科学 2022-02-28 Kaiwen Tan , Weixian Huang , Xiaofeng Liu , Jinlong Hu , Shoubin Dong

Prevalent cohort sampling is commonly used to study the natural history of a disease when the disease is rare or it usually takes a long time to observe the failure event. It is known, however, that the collected sample in this situation is…

统计方法学 · 统计学 2022-09-05 Omidali Aghababaei Jazi

Medical practitioners use survival models to explore and understand the relationships between patients' covariates (e.g. clinical and genetic features) and the effectiveness of various treatment options. Standard survival models like the…

So-called unsupervised anomaly detection is better described as semi-supervised, as it assumes all training data are nominal. This assumption simplifies training but requires manual data curation, introducing bias and limiting adaptability.…

计算机视觉与模式识别 · 计算机科学 2025-10-29 Muhammad Aqeel , Shakiba Sharifi , Marco Cristani , Francesco Setti

The study explores Artificial Intelligence (AI) powered modeling to predict the evolution of cancer tumor cells in mice under different forms of treatment. The AI models are analyzed against varying ambient and systemic parameters, e.g.…

Survival prediction is a major concern for cancer management. Deep survival models based on deep learning have been widely adopted to perform end-to-end survival prediction from medical images. Recent deep survival models achieved promising…

图像与视频处理 · 电气工程与系统科学 2024-10-17 Mingyuan Meng , Bingxin Gu , Michael Fulham , Shaoli Song , Dagan Feng , Lei Bi , Jinman Kim

The absence of adequately sufficient expert-level tumor annotations hinders the effectiveness of supervised learning based opportunistic cancer screening on medical imaging. Clinical reports (that are rich in descriptive textual details)…

计算机视觉与模式识别 · 计算机科学 2024-05-24 Guangyu Guo , Jiawen Yao , Yingda Xia , Tony C. W. Mok , Zhilin Zheng , Junwei Han , Le Lu , Dingwen Zhang , Jian Zhou , Ling Zhang

Semi-supervised learning reduces the costly manual annotation burden in medical image segmentation. A popular approach is the mean teacher (MT) strategy, which applies consistency regularization using a temporally averaged teacher model. In…

计算机视觉与模式识别 · 计算机科学 2025-11-10 Pengchen Zhang , Alan J. X. Guo , Sipin Luo , Zhe Han , Lin Guo

We present a semi-supervised algorithm for lung cancer screening in which a 3D Convolutional Neural Network (CNN) is trained using the Expectation-Maximization (EM) meta-algorithm. Semi-supervised learning allows a smaller labelled data-set…

机器学习 · 计算机科学 2020-10-06 Sumeet Menon , David Chapman , Phuong Nguyen , Yelena Yesha , Michael Morris , Babak Saboury

Survival analysis is a challenging variation of regression modeling because of the presence of censoring, where the outcome measurement is only partially known, due to, for example, loss to follow up. Such problems come up frequently in…

机器学习 · 计算机科学 2022-06-28 Chirag Nagpal , Steve Yadlowsky , Negar Rostamzadeh , Katherine Heller

Survival analysis/time-to-event models are extremely useful as they can help companies predict when a customer will buy a product, churn or default on a loan, and therefore help them improve their ROI. In this paper, we introduce a new…

机器学习 · 统计学 2018-01-18 Stephane Fotso