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The United States is currently experiencing an unprecedented opioid crisis, and opioid overdose has become a leading cause of injury and death. Effective opioid addiction recovery calls for not only medical treatments, but also behavioral…

Overdose related to prescription opioids have reached an epidemic level in the US, creating an unprecedented national crisis. This has been exacerbated partly due to the lack of tools for physicians to help predict the risk of whether a…

Opioids are an effective analgesic for acute and chronic pain, but also carry a considerable risk of addiction leading to millions of opioid use disorder (OUD) cases and tens of thousands of premature deaths in the United States yearly.…

The United States is experiencing an opioid epidemic, and there were more than 10 million opioid misusers aged 12 or older each year. Identifying patients at high risk of Opioid Use Disorder (OUD) can help to make early clinical…

The United States is in the midst of an opioid epidemic with recent estimates indicating that more than 130 people die every day due to drug overdose. The over-prescription and addiction to opioid painkillers, heroin, and synthetic opioids,…

The opioid epidemic is a crisis that has plagued the United States (US) for decades. One central issue is inequitable access to treatment for opioid use disorder (OUD), which puts certain populations at a higher risk of opioid overdose. We…

Opioid use disorder (OUD) is a chronic and relapsing condition that involves the continued and compulsive use of opioids despite harmful consequences. The development of medications with improved efficacy and safety profiles for OUD…

The opioid crisis has been one of the most critical society concerns in the United States. Although the medication assisted treatment (MAT) is recognized as the most effective treatment for opioid misuse and addiction, the various side…

In the last decade, the United States has lost more than 500,000 people from an overdose involving prescription and illicit opioids making it a national public health emergency (USDHHS, 2017). Medical practitioners require robust and timely…

Opioid Use Disorder (OUD) has emerged as a significant global public health issue, with complex multifaceted conditions. Due to the lack of effective treatment options for various conditions, there is a pressing need for the discovery of…

Opioid use disorder (OUD) continuously poses major public health challenges and social implications worldwide with dramatic rise of opioid dependence leading to potential abuse. Despite that a few pharmacological agents have been approved…

Increasing rates of opioid drug abuse and heightened prevalence of online support communities underscore the necessity of employing data mining techniques to better understand drug addiction using these rapidly developing online resources.…

Opioid Use Disorder (OUD) is a public health crisis costing the US billions of dollars annually in healthcare, lost workplace productivity, and crime. Analyzing longitudinal healthcare data is critical in addressing many real-world problems…

Understanding the neurobiology of opioid use disorder (OUD) using resting-state functional magnetic resonance imaging (rs-fMRI) may help inform treatment strategies to improve patient outcomes. Recent literature suggests time-frequency…

Chronic pain (CP) and opioid use disorder (OUD) are common and interrelated chronic medical conditions. Currently, there is a paucity of evidence-based integrated treatments for CP and OUD among individuals receiving medication for opioid…

Introduction: Chronic pain patients are at increased risk of opioid-misuse. Less is known about the unique risk conferred by each pain-management treatment, as treatments are typically implemented together, confounding their independent…

Opioid addiction is a severe public health threat in the U.S, causing massive deaths and many social problems. Accurate relapse prediction is of practical importance for recovering patients since relapse prediction promotes timely relapse…

Opioid addiction has become a global epidemic and a national health crisis in recent years, with the number of opioid overdose fatalities steadily increasing since the 1990s. In contrast to the dynamics of a typical illicit drug or disease…

Major depressive disorder (MDD) is a heterogeneous condition; multiple underlying neurobiological substrates could be associated with treatment response variability. Understanding the sources of this variability and predicting outcomes has…

Substance use disorders (SUDs) are a serious public health concern in the United States. Alcohol and cannabis are two of the most widely used substances. For adolescent/youth users of alcohol or cannabis, we propose a joint Bayesian…