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Erythrocyte Sedimentation Rate (ESR) is a clinical parameter used as a non-specific marker for inflammation, and recent studies have shown that it is linked to the collapse of the gel formed by red blood cells (RBCs) at physiological…

软凝聚态物质 · 物理学 2023-07-07 Thomas John , Lars Kaestner , Christian Wagner , Alexis Darras

Cell tracking and segmentation assist biologists in extracting insights from large-scale microscopy time-lapse data. Driven by local accuracy metrics, current tracking approaches often suffer from a lack of long-term consistency and the…

计算机视觉与模式识别 · 计算机科学 2025-06-30 Timo Kaiser , Maximilian Schier , Bodo Rosenhahn

We generalize the SiZer of Chaudhuri and Marron (J. Amer. Statist. Assoc. 94 (1999) 807-823, Ann. Statist. 28 (2000) 408-428) for the detection of shape parameters of densities on the real line to the case of circular data. It turns out…

In cardiac cells, structural organization is an important indicator of cell maturity and healthy function. Healthy cardiomyocytes exhibit well-aligned morphology with densely packed and organized sarcomeres. Immature or diseased…

定量方法 · 定量生物学 2025-02-03 Saeed Mohammadzadeh , Emma Lejeune

We propose a deep learning method to model and generate synthetic aortic shapes based on representing shapes as the zero-level set of a neural signed distance field, conditioned by a family of trainable embedding vectors with encode the…

计算机视觉与模式识别 · 计算机科学 2024-09-25 Andrei Gasparovici , Alex Serban

Endovascular coil embolization is one of the primary treatment techniques for cerebral aneurysms. Although it is a well established and minimally invasive method, it bears the risk of sub-optimal coil placement which can lead to incomplete…

计算工程、金融与科学 · 计算机科学 2024-02-06 Fabian Holzberger , Markus Muhr , Barbara Wohlmuth

Single cell segmentation is critical and challenging in live cell imaging data analysis. Traditional image processing methods and tools require time-consuming and labor-intensive efforts of manually fine-tuning parameters. Slight variations…

A topology preserving skeleton is a synthetic representation of an object that retains its topology and many of its significant morphological properties. The process of obtaining the skeleton, referred to as skeletonization or thinning, is…

计算机视觉与模式识别 · 计算机科学 2015-06-17 Paweł Dłotko , Ruben Specogna

Clustering, as an unsupervised technique, plays a pivotal role in various data analysis applications. Among clustering algorithms, Spectral Clustering on Euclidean Spaces has been extensively studied. However, with the rapid evolution of…

机器学习 · 计算机科学 2024-12-09 Sagar Ghosh , Swagatam Das

This paper proposes a novel automatic classification framework for the recognition of five types of white blood cells. Segmenting complete white blood cells from blood smears images and extracting advantageous features from them remain…

计算机视觉与模式识别 · 计算机科学 2020-09-07 Na Dong , Meng-die Zhai , Jian-fang Chang , Chun-ho Wu

The mechanical behaviour and symmetry-breaking shape deformation of red blood cells subjected to shear flows is used to demonstrate that far from being random fluids, both the membrane and cytoplasm of every biological cell undergo…

综合物理 · 物理学 2007-05-23 Juanita Lofthouse

The fast blood stream of animals is associated with large shear stresses. Consequently, blood cells have evolved a special morphology and a specific internal architecture allowing them to maintain their integrity over several weeks. For…

亚细胞过程 · 定量生物学 2022-10-12 Serge Dmitrieff , Adolfo Alsina , Aastha Mathur , François Nédélec

The paper explores mathematical methods that differentiate regular and chaotic time series, specifically for identifying pathological fistulas. It proposes a noise-resistant method for classifying responding rows of normally and…

医学物理 · 物理学 2023-09-27 Vasilii A. Gromov , E. I. Zvorykina , Yurii N. Beschastnov , Majid Sohrabi

The vertex model is widely used to describe the dynamics of epithelial tissues, because of its simplicity and versatility and the direct inclusion of biophysical parameters. Here, it is shown that quite generally, when cells modify their…

软凝聚态物质 · 物理学 2020-11-25 Fernanda Perez-Verdugo , Jean-Francois Joanny , Rodrigo Soto

How the cells break symmetry and organize their edge activity to move directionally is a fun- damental question in cell biology. Physical models of cell motility commonly rely on gradients of regulatory factors and/or feedback from the…

Vertebrae localization, segmentation and identification in CT images is key to numerous clinical applications. While deep learning strategies have brought to this field significant improvements over recent years, transitional and…

图像与视频处理 · 电气工程与系统科学 2022-06-27 Di Meng , Edmond Boyer , Sergi Pujades

Cellular populations are typically heterogenous collections of cells at different points in their respective cell cycles, each with a cell cycle time that varies from individual to individual. As a result, true single-cell behavior,…

定量方法 · 定量生物学 2013-07-02 Marisa C. Eisenberg , Joshua N. Ash , Dan Siegal-Gaskins

We present an adaptive geometry in which the yardstick co-deforms with space itself, formulated on cellular spaces where length is a count: distances are shortest cell-crossing counts. No cell shape, angles, or embedding are assumed; the…

综合数学 · 数学 2026-03-05 Shlomo Barak , George Salman

We present a volumetric mesh-based algorithm for parameterizing the placenta to a flattened template to enable effective visualization of local anatomy and function. MRI shows potential as a research tool as it provides signals directly…

计算机视觉与模式识别 · 计算机科学 2021-11-16 S. Mazdak Abulnaga , Esra Abaci Turk , Mikhail Bessmeltsev , P. Ellen Grant , Justin Solomon , Polina Golland

Mechanical properties of the cell are important biomarkers for probing its architectural changes caused by cellular processes and/or pathologies. The development of microfluidic technologies have enabled measuring cell mechanics at…

软凝聚态物质 · 物理学 2021-05-19 Moslem Moradi , Ehssan Nazockdast