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Discrete diffusion or flow models could enable faster and more controllable sequence generation than autoregressive models. We show that na\"ive linear flow matching on the simplex is insufficient toward this goal since it suffers from…

生物大分子 · 定量生物学 2024-06-03 Hannes Stark , Bowen Jing , Chenyu Wang , Gabriele Corso , Bonnie Berger , Regina Barzilay , Tommi Jaakkola

Uniform-state discrete diffusion models excel at few-step generation and guidance due to their ability to self-correct, making them preferred over autoregressive or Masked diffusion models in these settings. However, their sampling quality…

机器学习 · 计算机科学 2026-05-19 Justin Deschenaux , Caglar Gulcehre , Subham Sekhar Sahoo

Normal and anomalous diffusion are ubiquitous in many complex systems [1] . Here, we define a time and space generalized diffusion equation (GDE), which uses fractional-time derivatives and transformed d-path Laplacian operators on…

物理与社会 · 物理学 2022-02-02 Fernando Diaz-Diaz , Ernesto Estrada

The Wright-Fisher (W-F) diffusion model serves as a foundational framework for interpreting population evolution through allele frequency dynamics over time. Despite the known transition probability between consecutive generations, an exact…

统计方法学 · 统计学 2024-06-24 Tania Roa , María Inés Fariello , Gerardo Martínez , José León

We study a family of n-dimensional diffusions, taking values in the unit simplex of vectors with nonnegative coordinates that add up to one. These processes satisfy stochastic differential equations which are similar to the ones for the…

概率论 · 数学 2013-03-15 Soumik Pal

Mathematical models of genetic evolution often come in pairs, connected by a so-called duality relation. The most seminal example are the Wright-Fisher diffusion and the Kingman coalescent, where the former describes the stochastic…

概率论 · 数学 2024-02-02 Jere Koskela , Krzysztof Łatuszyński , Dario Spanò

Diffusion models have emerged as a powerful class of generative models, achieving state-of-the-art results in continuous data domains such as image and video generation. Their core mechanism involves a forward diffusion process that…

计算与语言 · 计算机科学 2025-07-10 Ashen Weligalle

New ideas and technologies adopted by a small number of individuals occasionally spread globally through a complex web of social ties. Here, we present a simple and general approximation method, namely, a message-passing approach, that…

物理与社会 · 物理学 2022-09-01 Teruyoshi Kobayashi , Tomokatsu Onaga

Denoising models such as Diffusion or Flow Matching have recently advanced generative modeling for discrete structures, yet most approaches either operate directly in the discrete state space, causing abrupt state changes. We introduce…

机器学习 · 计算机科学 2026-03-31 Yoann Boget , Alexandros Kalousis

While traditional recommendation techniques have made significant strides in the past decades, they still suffer from limited generalization performance caused by factors like inadequate collaborative signals, weak latent representations,…

信息检索 · 计算机科学 2024-09-17 Jianghao Lin , Jiaqi Liu , Jiachen Zhu , Yunjia Xi , Chengkai Liu , Yangtian Zhang , Yong Yu , Weinan Zhang

Diffusion models typically operate in the standard framework of generative modelling by producing continuously-valued datapoints. To this end, they rely on a progressive Gaussian smoothing of the original data distribution, which admits an…

机器学习 · 计算机科学 2022-10-27 Pierre H. Richemond , Sander Dieleman , Arnaud Doucet

Generative models can be categorized into two types: explicit generative models that define explicit density forms and allow exact likelihood inference, such as score-based diffusion models (SDMs) and normalizing flows; implicit generative…

机器学习 · 统计学 2023-07-06 Jingwei Zhang , Han Shi , Jincheng Yu , Enze Xie , Zhenguo Li

The stationary distribution of a sample taken from a Wright-Fisher diffusion with general small mutation rates is found using a coalescent approach. The approximation is equivalent to having at most one mutation in the coalescent tree to…

种群与进化 · 定量生物学 2018-10-31 Conrad J. Burden , Robert C. Griffiths

Diffusion models have had a profound impact on many application areas, including those where data are intrinsically infinite-dimensional, such as images or time series. The standard approach is first to discretize and then to apply…

机器学习 · 统计学 2025-06-09 Jakiw Pidstrigach , Youssef Marzouk , Sebastian Reich , Sven Wang

The Wright--Fisher diffusion is important in population genetics in modelling the evolution of allele frequencies over time subject to the influence of biological phenomena such as selection, mutation, and genetic drift. Simulating paths of…

种群与进化 · 定量生物学 2023-01-16 Jaromir Sant , Paul A. Jenkins , Jere Koskela , Dario Spanò

Diffusion models have achieved unprecedented performance in generative modeling. The commonly-adopted formulation of the latent code of diffusion models is a sequence of gradually denoised samples, as opposed to the simpler (e.g., Gaussian)…

计算机视觉与模式识别 · 计算机科学 2022-12-08 Chen Henry Wu , Fernando De la Torre

Diffusion models, a powerful and universal generative AI technology, have achieved tremendous success in computer vision, audio, reinforcement learning, and computational biology. In these applications, diffusion models provide flexible…

机器学习 · 计算机科学 2024-04-12 Minshuo Chen , Song Mei , Jianqing Fan , Mengdi Wang

Study sample sizes in human genetics are growing rapidly, and in due course it will become routine to analyze samples with hundreds of thousands if not millions of individuals. In addition to posing computational challenges, such large…

种群与进化 · 定量生物学 2015-06-24 Anand Bhaskar , Andrew G. Clark , Yun S. Song

Diffusion distillation is a widely used technique to reduce the sampling cost of diffusion models, yet it often requires extensive training, and the student performance tends to be degraded. Recent studies show that incorporating a GAN…

机器学习 · 计算机科学 2025-06-12 Bowen Zheng , Tianming Yang

We propose a class of structured diffusion models, in which the prior distribution is chosen as a mixture of Gaussians, rather than a standard Gaussian distribution. The specific mixed Gaussian distribution, as prior, can be chosen to…

机器学习 · 计算机科学 2024-10-28 Nanshan Jia , Tingyu Zhu , Haoyu Liu , Zeyu Zheng