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Generative models on discrete state-spaces have a wide range of potential applications, particularly in the domain of natural sciences. In continuous state-spaces, controllable and flexible generation of samples with desired properties has…

机器学习 · 计算机科学 2025-03-27 Hunter Nisonoff , Junhao Xiong , Stephan Allenspach , Jennifer Listgarten

Diffusion generative models have recently been applied to domains where the available data can be seen as a discretization of an underlying function, such as audio signals or time series. However, these models operate directly on the…

机器学习 · 计算机科学 2023-02-28 Gavin Kerrigan , Justin Ley , Padhraic Smyth

Diffusion models generate high-quality synthetic data. They operate by defining a continuous-time forward process which gradually adds Gaussian noise to data until fully corrupted. The corresponding reverse process progressively "denoises"…

We give a new algorithm for learning mixtures of $k$ Gaussians (with identity covariance in $\mathbb{R}^n$) to TV error $\varepsilon$, with quasi-polynomial ($O(n^{\text{poly\,log}\left(\frac{n+k}{\varepsilon}\right)})$) time and sample…

机器学习 · 计算机科学 2025-03-05 Khashayar Gatmiry , Jonathan Kelner , Holden Lee

Discrete diffusion models have recently gained significant prominence in applications involving natural language and graph data. A key factor influencing their effectiveness is the efficiency of discretized samplers. Among these,…

机器学习 · 计算机科学 2025-11-03 Yuchen Liang , Yingbin Liang , Lifeng Lai , Ness Shroff

Diffusion models (DMs) are a class of generative machine learning methods that sample a target distribution by transforming samples of a trivial (often Gaussian) distribution using a learned stochastic differential equation. In standard…

统计力学 · 物理学 2024-08-15 Luke Causer , Grant M. Rotskoff , Juan P. Garrahan

Despite Flow Matching and diffusion models having emerged as powerful generative paradigms for continuous variables such as images and videos, their application to high-dimensional discrete data, such as language, is still limited. In this…

机器学习 · 计算机科学 2024-11-06 Itai Gat , Tal Remez , Neta Shaul , Felix Kreuk , Ricky T. Q. Chen , Gabriel Synnaeve , Yossi Adi , Yaron Lipman

Reaction--diffusion mechanism are a robust paradigm that can be used to represent many biological and physical phenomena over multiple spatial scales. Applications include intracellular dynamics, the migration of cells and the patterns…

定量方法 · 定量生物学 2021-01-01 Cameron A. Smith , Christian A. Yates

We introduce the concept of Randomly Modulated Gaussian Processes as a unifying framework for modeling, analyzing and classifying anomalous diffusion models in heterogeneous media. This formulation incorporates correlations in the…

生物物理 · 物理学 2026-03-16 Yann Lanoiselée , Denis S. Grebenkov , Gianni Pagnini

Various biological cells secrete diffusing chemical compounds into their environment for communication purposes. Secretion usually takes place over the cell membrane in a spatially heterogeneous manner. Mathematical models of these…

数值分析 · 数学 2025-11-20 Qiyao Peng , Sander C. Hille

Diffusion models (DMs) are a powerful generative framework that have attracted significant attention in recent years. However, the high computational cost of training DMs limits their practical applications. In this paper, we start with a…

机器学习 · 计算机科学 2024-04-12 Tianshuo Xu , Peng Mi , Ruilin Wang , Yingcong Chen

Multiscale spatial structure complicates temporal prediction because small-scale spatial fluctuations influence large-scale evolution, yet resolving all scales is often intractable. Standard diffusion models do not address this problem…

流体动力学 · 物理学 2026-04-02 Yuki Yasuda , Tobias Bischoff

The increasing availability of population-level allele frequency data across one or more related populations necessitates the development of methods that can efficiently estimate population genetics parameters, such as the strength of…

统计计算 · 统计学 2017-11-09 Jeffrey J. Gory , Radu Herbei , Laura S. Kubatko

This survey focuses on the most important aspects of the mathematical theory of population genetic models of selection and migration between discrete niches. Such models are most appropriate if the dispersal distance is short compared to…

种群与进化 · 定量生物学 2019-12-13 Reinhard Bürger

Generative diffusion models showed high success in many fields with a powerful theoretical background. They convert the data distribution to noise and remove the noise back to obtain a similar distribution. Many existing reviews focused on…

机器学习 · 计算机科学 2024-09-19 Melike Nur Yeğin , Mehmet Fatih Amasyalı

Diffusion models have demonstrated exceptional performances in various fields of generative modeling, but suffer from slow sampling speed due to their iterative nature. While this issue is being addressed in continuous domains, discrete…

机器学习 · 计算机科学 2025-05-12 Satoshi Hayakawa , Yuhta Takida , Masaaki Imaizumi , Hiromi Wakaki , Yuki Mitsufuji

Diffusion Models generate data by reversing a stochastic diffusion process, progressively transforming noise into structured samples drawn from a target distribution. Recent theoretical work has shown that this backward dynamics can undergo…

机器学习 · 计算机科学 2026-02-05 Beatrice Achilli , Marco Benedetti , Giulio Biroli , Marc Mézard

Diffusion models have emerged as a powerful new family of deep generative models with record-breaking performance in many applications, including image synthesis, video generation, and molecule design. In this survey, we provide an overview…

机器学习 · 计算机科学 2025-09-30 Ling Yang , Zhilong Zhang , Yang Song , Shenda Hong , Runsheng Xu , Yue Zhao , Wentao Zhang , Bin Cui , Ming-Hsuan Yang

We present a concise, self-contained derivation of diffusion-based generative models. Starting from basic properties of Gaussian distributions (densities, quadratic expectations, re-parameterisation, products, and KL divergences), we…

机器学习 · 计算机科学 2025-11-18 Sepehr Maleki , Negar Pourmoazemi

In populations competing for resources, it is natural to ask whether consuming fewer resources provides any selective advantage. To answer this question, we propose a Wright- Fisher model with two types of individuals: the inefficient…