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An ability to map seizure-generating brain tissue, i.e., the seizure onset zone (SOZ), without recording actual seizures could reduce the duration of invasive EEG monitoring for patients with drug-resistant epilepsy. A widely-adopted…

Epileptic seizure detection and classification in clinical electroencephalogram data still is a challenge, and only low sensitivity with a high rate of false positives has been achieved with commercially available seizure detection tools,…

信号处理 · 电气工程与系统科学 2020-07-14 Tomas Iesmantas , Robertas Alzbutas

Objective: The aim of this study is to develop an efficient and reliable epileptic seizure prediction system using intracranial EEG (iEEG) data, especially for people with drug-resistant epilepsy. The prediction procedure should yield…

神经与进化计算 · 计算机科学 2019-04-09 Ramy Hussein , Mohamed Osama Ahmed , Rabab Ward , Z. Jane Wang , Levin Kuhlmann , Yi Guo

Epilepsy is one of the most common neurological diseases globally (around 50 million people worldwide). Fortunately, up to 70% of people with epilepsy could live seizure-free if properly diagnosed and treated, and a reliable technique to…

信号处理 · 电气工程与系统科学 2024-10-25 Abdul Aziz , Nhat Pham , Neel Vora , Cody Reynolds , Jaime Lehnen , Pooja Venkatesh , Zhuoran Yao , Jay Harvey , Tam Vu , Kan Ding , Phuc Nguyen

Epilepsy is a neurological disease characterized by recurrent and spontaneous seizures. It affects approximately 50 million people worldwide. In majority of the cases accurate diagnosis of the disease can be made without using any…

定量方法 · 定量生物学 2013-04-05 Roxana A. Stephanescu , R. G. Shivakeshavan , Sachin S. Talathi

Arrhythmias are irregularities in the hearts electrical system which cause rapid and irregular heartbeats. These heart conditions affect over 33 million people globally and significantly increase the risk of severe complications, including…

信号处理 · 电气工程与系统科学 2024-10-29 Praveen Kumar Pandian Shanmuganathan , Vatsal Sivaratri

Identifying seizure activities in non-stationary electroencephalography (EEG) is a challenging task, since it is time-consuming, burdensome, and dependent on expensive human resources and subject to error and bias. A computerized seizure…

信号处理 · 电气工程与系统科学 2020-04-29 S. Sheykhivand , T. Yousefi Rezaii , Z. Mousavi , A. Delpak , A. Farzamnia

Controlling the surrounding world and predicting future events has always seemed like a dream, but that could become a reality using a Brain-Computer/Machine Interface (BCI/BMI). Epilepsy is a group of neurological diseases characterized by…

信号处理 · 电气工程与系统科学 2019-06-10 Zaghloul Saad Zaghloul , Magdy Bayoumi

Identifying epileptic seizures through analysis of the electroencephalography (EEG) signal becomes a standard method for the diagnosis of epilepsy. Manual seizure identification on EEG by trained neurologists is time-consuming,…

机器学习 · 计算机科学 2019-06-07 X. Yao , X. Li , Q. Ye , Y. Huang , Q. Cheng , G. -Q. Zhang

Neural oscillations are considered to be brain-specific signatures of information processing and communication in the brain. They also reflect pathological brain activity in neurological disorders, thus offering a basis for diagnoses and…

神经元与认知 · 定量生物学 2023-10-23 Tena Dubcek , Debora Ledergerber , Jana Thomann , Giovanna Aiello , Marc Serra-Garcia , Lukas Imbach , Rafael Polania

Intracranial recordings in epilepsy patients are increasingly utilized to gain insight into the electrophysiological mechanisms of human cognition. There are currently several practical limitations to conducting research with these…

神经元与认知 · 定量生物学 2021-06-23 Omer E Ashmaig , Liberty S Hamilton , Pradeep Modur , Robert J Buchanan , Alison R Preston , Andrew J Watrous

Recent advances in neurotechnologies and decades of scientific and clinical research have made closed-loop electrical neuromodulation one of the most promising avenues for the treatment of drug-resistant epilepsy (DRE), a condition that…

系统与控制 · 电气工程与系统科学 2026-03-30 Gagan Acharya , Erfan Nozari

Recent advances in control theory yield closed-loop neurostimulations for suppressing epileptiform seizures. These advances are illustrated by computer experiments which are easy to implement and to tune. The feedback synthesis is provided…

系统与控制 · 电气工程与系统科学 2024-10-03 Cédric Join , D. Blair Jovellar , Emmanuel Delaleau , Michel Fliess

Epilepsy is a disorder of the nervous system that can affect people of any age group. With roughly 50 million people worldwide diagnosed with the disorder, it is one of the most common neurological disorders. The EEG is an indispensable…

种群与进化 · 定量生物学 2022-02-21 Niamh McCallan , Scot Davidson , Kok Yew Ng , Pardis Biglarbeigi , Dewar Finlay , Boon Leong Lan , James McLaughlin

Epilepsy is a prevalent neurological disorder affecting 50 million individuals worldwide and 1.2 million Americans. There exist millions of pediatric patients with intractable epilepsy, a condition in which seizures fail to come under…

机器学习 · 计算机科学 2023-09-07 Bliss Singhal , Fnu Pooja

Epileptic seizures are one of the most well-known dysfunctions of the nervous system. During a seizure, a highly synchronized behavior of neural activity is observed that can cause symptoms ranging from mild sensual malfunctions to the…

神经元与认知 · 定量生物学 2011-08-01 Christian Kuehn , Christian Meisel

Early management and better clinical outcomes for epileptic patients depend on seizure prediction. The accuracy and false alarm rates of existing systems are often compromised by their dependence on static thresholds and basic…

信号处理 · 电气工程与系统科学 2025-01-29 Mathan Kumar Mounagurusamy , Thiyagarajan V S , Abdur Rahman , Shravan Chandak , D. Balaji , Venkateswara Rao Jallepalli

This paper introduces an innovative framework designed for progressive (granular in time to onset) prediction of seizures through the utilization of a Deep Learning (DL) methodology based on non-invasive multi-modal sensor networks.…

信号处理 · 电气工程与系统科学 2024-11-05 Ali Saeizadeh , Douglas Schonholtz , Joseph S. Neimat , Pedram Johari , Tommaso Melodia

Epilepsy is a neurological disorder characterized by recurrent seizures affecting more than 70 million people worldwide. Often, an individual with epilepsy is more likely to experience subsequent seizures following an initial seizure, a…

统计方法学 · 统计学 2026-05-22 Karen Kanaster , Giovani L. Silva , Peter Mueller , Jacob Pellinen , Elizabeth Juarez-Colunga

Epileptic seizures are characterized by abnormal and excessive neural activity, where cortical network dynamics seem to become unstable. However, most of the time, during seizure-free periods, cortex of epilepsy patients shows perfectly…

神经元与认知 · 定量生物学 2021-04-06 Annika Hagemann , Jens Wilting , Bita Samimizad , Florian Mormann , Viola Priesemann