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The effect of mechanical interactions between cells in the spreading of bacterial populations was investigated in one-dimensional space. A continuum-mechanics approach, comprising cell migration, proliferation, and exclusion processes, was…

生物物理 · 物理学 2015-12-15 Waipot Ngamsaad , Suthep Suantai

Single and collective cell migration are fundamental processes critical for physiological phenomena ranging from embryonic development and immune response to wound healing and cancer metastasis. To understand cell migration from a physical…

生物物理 · 物理学 2023-10-10 David B. Brückner , Chase P. Broedersz

Numerous experimental studies have demonstrated that the microenvironment is a key regulator influencing the proliferative and migrative potentials of species. Spatial and temporal disturbances lead to adverse and hazardous…

种群与进化 · 定量生物学 2015-10-07 Venkata. S. K. Manem , Kamran Kaveh , Mohammad Kohandel , Siv Sivaloganathan

Population dynamics reflects an underlying birth-death process, where the rates associated with different events may depend on external environmental conditions and on the population density. A whole family of simple and popular…

种群与进化 · 定量生物学 2019-07-03 Yitzhak Yahalom , Bnaya Steinmetz , Nadav M. Shnerb

The metapopulation framework is adopted in a wide array of disciplines to describe systems of well separated yet connected subpopulations. The subgroups or patches are often represented as nodes in a network whose links represent the…

物理与社会 · 物理学 2013-03-27 Suyu Liu , Andrea Baronchelli , Nicola Perra

The rate at which individual bacterial cells grow depends on the concentrations of cellular components such as ribosomes and proteins. These concentrations continuously fluctuate over time and are inherited from mother to daughter cells,…

种群与进化 · 定量生物学 2024-08-21 Yaïr Hein , Farshid Jafarpour

I study a population model in which the reproduction rate lambda is inherited with mutation, favoring fast reproducers in the short term, but conflicting with a process that eliminates agglomerations of individuals. The model is a variant…

统计力学 · 物理学 2021-06-02 Ronald Dickman

Symmetries represent a fundamental constraint for physical systems and relevant new phenomena often emerge as a consequence of their breaking. An important example is provided by space- and time-translational invariance in statistical…

统计力学 · 物理学 2012-12-21 Matteo Marcuzzi , Andrea Gambassi , Michel Pleimling

We describe a continuous-time modelling framework for biological population dynamics that accounts for demographic noise. In the spirit of the methodology used by statistical physicists, transitions between the states of the system are…

种群与进化 · 定量生物学 2018-07-19 George W. A. Constable , Alan J. McKane

We consider the diffusion-advection problem in two simple cellular flow models (often invoked as examples for subdiffusive tracer's motion) and concentrate on the intermediate time range, in which the tracer's motion indeed may show…

流体动力学 · 物理学 2016-09-28 Patrick Pöschke , Igor M. Sokolov , Alexander A. Nepomnyashchy , Michael A. Zaks

Structured populations are ubiquitous across the biological sciences. Mathematical models of these populations allow us to understand how individual physiological traits drive the overall dynamics in aggregate. For example, linear age- or…

偏微分方程分析 · 数学 2022-04-25 Sabina L. Altus , Jeffrey C. Cameron , David M. Bortz

Several independent observations have suggested that catastrophe transition in microtubules is not a first-order process, as is usually assumed. Recent {\it in vitro} observations by Gardner et al.[ M. K. Gardner et al., Cell {\bf147}, 1092…

亚细胞过程 · 定量生物学 2015-07-02 V. Jemseena , Manoj Gopalakrishnan

Ignoring the differences between countries, human reproductive and dispersal behaviors can be described by some standardized models, so whether there is a universal law of population growth hidden in the abundant and unstructured data from…

物理与社会 · 物理学 2024-02-08 Jiajun Ma , Qinghua Chen , Xiaosong Chen , Jingfang Fan , Xiaomeng Li , Yi Shi

Although the concepts of age, survival and transit time have been widely used in many fields, including population dynamics, chemical engineering, and hydrology, a comprehensive mathematical framework is still missing. Here we discuss…

种群与进化 · 定量生物学 2016-02-17 Salvatore Calabrese , Amilcare Porporato

Diffusion processes are central to human interactions. One common prediction of the current modeling frameworks is that initial spreading dynamics follow exponential growth. Here, we find that, ranging from mobile handsets to automobiles,…

物理与社会 · 物理学 2019-05-22 Ching Jin , Chaoming Song , Johannes Bjelland , Geoffrey Canright , Dashun Wang

Due to its ability to summarise 'real-time' epidemic behaviour, the time-dependent reproduction number, Rt, is a useful metric for tracking pathogen transmission and quantifying the effects of interventions during infectious disease…

种群与进化 · 定量生物学 2026-03-12 Ioana Bouros , Robin Thompson , David Gavaghan , Ben Lambert

Modeling how individuals evolve over time is a fundamental problem in the natural and social sciences. However, existing datasets are often cross-sectional with each individual observed only once, making it impossible to apply traditional…

Cells grown in culture act as a model system for analyzing the effects of anticancer compounds, which may affect cell behavior in a cell cycle position-dependent manner. Cell synchronization techniques have been generally employed to…

偏微分方程分析 · 数学 2019-02-28 Pierre Gabriel , Shawn P. Garbett , Vito Quaranta , Darren R. Tyson , Glenn F. Webb

This paper considers a nonlinear model for population dynamics with age structure. The fertility rate with respect to age is non constant and has the form proposed by [17]. Moreover, its multiplicative structure and the multiplicative…

综合数学 · 数学 2023-12-06 Dragos-Patru Covei , Traian A. Pirvu , Catalin Sterbeti

The flow in a Hele-Shaw cell with a time-increasing gap poses a unique shrinking interface problem. When the upper plate of the cell is lifted perpendicularly at a prescribed speed, the exterior less viscous fluid penetrates the interior…

流体动力学 · 物理学 2021-01-20 Meng Zhao , Zahra Niroobakhsh , John Lowengrub , Shuwang Li