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Current analysis of tumor proliferation, the most salient prognostic biomarker for invasive breast cancer, is limited to subjective mitosis counting by pathologists in localized regions of tissue images. This study presents the first…

计算机视觉与模式识别 · 计算机科学 2016-10-12 Manan Shah , Christopher Rubadue , David Suster , Dayong Wang

In this paper, we develop a deep learning approach for the accurate solution of challenging problems of near-field microscopy that leverages the powerful framework of physics-informed neural networks (PINNs) for the inversion of the complex…

光学 · 物理学 2024-06-12 Yuyao Chen , Luca Dal Negro

This dissertation investigates physics-informed neural networks (PINNs) as candidate models for encoding governing equations, and assesses their performance on experimental data from two different systems. The first system is a simple…

机器学习 · 计算机科学 2024-01-09 Hamza Alsharif

The prediction plays the important role in detecting efficient protection and therapy of cancer. The prediction of mutations in gene needs a diagnostic and classification, which is based on the whole database (big dataset), to reach…

机器学习 · 计算机科学 2016-08-10 Ayad Ghany Ismaeel , Dina Yousif Mikhail

Achieving clean combustion systems is crucial in terms of solving environmental impacts, decarbonization needs and sustainability matters. Traditional combustion modeling techniques via computational fluid dynamics with accurate chemical…

流体动力学 · 物理学 2025-09-11 Mahmood Mousavi , Caleb Caldwell , Jacob Baltes , Muteb Aljasem , Bok Jik Lee

We propose a model for describing the growth on an untreated tumor, which is characterized in a simple way by a minimal number of parameters with a well-defined physical interpretation. The model is motivated by invoking the Master Equation…

种群与进化 · 定量生物学 2007-05-23 José F. Nieves , Marcelo R. Ubriaco

Physics-Informed Neural Networks (PINNs) represent a groundbreaking paradigm in scientific computing, seamlessly integrating the robust framework of deep learning with fundamental physical laws. This paper meticulously applies the standard…

数值分析 · 数学 2026-01-19 Ahmed Aberqi , Ahmed Miloudi

Deep learning has emerged as a prominent field in recent literature, showcasing the introduction of models that utilize transfer learning to achieve remarkable accuracies in the classification of brain tumor MRI images. However, the…

计算机视觉与模式识别 · 计算机科学 2023-08-15 Raza Imam , Mohammed Talha Alam

We present a deep transformation model for probabilistic regression. Deep learning is known for outstandingly accurate predictions on complex data but in regression tasks, it is predominantly used to just predict a single number. This…

机器学习 · 统计学 2020-04-02 Beate Sick , Torsten Hothorn , Oliver Dürr

Recent advances in cancer research largely rely on new developments in microscopic or molecular profiling techniques offering high level of detail with respect to either spatial or molecular features, but usually not both. Here, we present…

This paper deals with the cellular biological network analysis of the tumor-growth model, consisting of multiple spaces and time scales. In this paper, we present a model in graph simulation using ABM for tumor growth. In particular, we…

多智能体系统 · 计算机科学 2019-09-05 Ghazal Tashakor , Remo Suppi

We present a novel formulation for the calibration of a biophysical tumor growth model from a single-time snapshot, MRI scan of a glioblastoma patient. Tumor growth models are typically nonlinear parabolic partial differential equations…

定量方法 · 定量生物学 2020-06-30 Klaudius Scheufele , Shashank Subramanian , Andreas Mang , George Biros , Miriam Mehl

The utilization of Deep Neural Networks (DNNs) in physical science and engineering applications has gained traction due to their capacity to learn intricate functions. While large datasets are crucial for training DNN models in fields like…

机器学习 · 计算机科学 2025-08-05 Vamsi Sai Krishna Malineni , Suresh Rajendran

Tumors can manifest in various forms and in different areas of the human body. Brain tumors are specifically hard to diagnose and treat because of the complexity of the organ in which they develop. Detecting them in time can lower the…

图像与视频处理 · 电气工程与系统科学 2024-03-18 Antonio Curci , Andrea Esposito

We investigate the evolution of tumor growth relying on a nonlinear model of partial differential equations which incorporates mechanical laws for tissue compression combined with rules for nutrients availability and drug application.…

数值分析 · 数学 2016-02-23 Konstantina Trivisa , Franziska Weber

Physics-informed neural networks (PINNs) are revolutionizing science and engineering practice by bringing together the power of deep learning to bear on scientific computation. In forward modeling problems, PINNs are meshless partial…

机器学习 · 计算机科学 2023-11-28 Yicheng Wang , Xiaotian Han , Chia-Yuan Chang , Daochen Zha , Ulisses Braga-Neto , Xia Hu

Physics-informed Neural Networks (PINNs) is a method for numerical simulation that incorporates a loss function corresponding to the governing equations into a neural network. While PINNs have been explored for their utility in inverse…

声音 · 计算机科学 2024-06-18 Kazuya Yokota , Masataka Ogura , Masajiro Abe

Although physics-informed neural networks (PINNs) have shown great potential in dealing with nonlinear partial differential equations (PDEs), it is common that PINNs will suffer from the problem of insufficient precision or obtaining…

机器学习 · 计算机科学 2024-10-07 Feilong Jiang , Xiaonan Hou , Min Xia

One of the main goals of developmental biology is to reveal the gene regulatory networks (GRNs) underlying the robust differentiation of multipotent progenitors into precisely specified cell types. Most existing methods to infer GRNs from…

定量方法 · 定量生物学 2024-01-23 Maria Mircea , Diego Garlaschelli , Stefan Semrau

Brain tumors are serious health problems that require early diagnosis due to their high mortality rates. Diagnosing tumors by examining Magnetic Resonance Imaging (MRI) images is a process that requires expertise and is prone to error.…

计算机视觉与模式识别 · 计算机科学 2026-04-10 Mustafa Yurdakul , Şakir Taşdemir