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Unsupervised and semi-supervised ML methods such as variational autoencoders (VAE) have become widely adopted across multiple areas of physics, chemistry, and materials sciences due to their capability in disentangling representations and…

机器学习 · 计算机科学 2022-07-04 Arpan Biswas , Rama Vasudevan , Maxim Ziatdinov , Sergei V. Kalinin

In this paper, we present an approach for modeling bio-tissues that incorporates the variability in properties as part of their characteristics. This is achieved by considering the parameters of the model of a biomaterial to themselves be…

组织与器官 · 定量生物学 2013-12-11 Srikrishna Doraiswamy , Arun R. Srinivasa

Dynamic prediction of time-to-event outcomes using longitudinal data is highly useful in clinical research and practice. A common strategy is the joint modeling of longitudinal and time-to-event data. The shared random effect model has been…

统计方法学 · 统计学 2025-05-27 Wenhao Li , Zhe Yin , Liang Li

Large-scale longitudinal molecular profiling is now firmly established in biomedical research, prompted by the need to uncover coordinated biomarker trajectories reflecting the dynamics of underlying biological mechanisms and characterise…

统计方法学 · 统计学 2026-03-24 Salima Jaoua , Daniel Temko , Hélène Ruffieux

Cardiovascular disease (CVD) cohorts collect data longitudinally to study the association between CVD risk factors and event times. An important area of scientific research is to better understand what features of CVD risk factor…

统计方法学 · 统计学 2024-12-03 Mirajul Islam , Michael J. Daniels , Zeynab Aghabazaz , Juned Siddique

In recent years, disease mapping studies have become a routine application within geographical epidemiology and are typically analysed within a Bayesian hierarchical model formulation. A variety of model formulations for the latent level…

统计方法学 · 统计学 2016-01-07 Andrea Riebler , Sigrunn H. Sørbye , Daniel Simpson , Håvard Rue

In recent years, the growing availability of biomedical datasets featuring numerous longitudinal covariates has motivated the development of several multi-step methods for the dynamic prediction of survival outcomes. These methods employ…

统计方法学 · 统计学 2026-01-14 Mirko Signorelli , Sophie Retif

This paper takes a quick look at Bayesian joint models (BJM) for longitudinal and survival data. A general formulation for BJM is examined in terms of the sampling distribution of the longitudinal and survival processes, the conditional…

统计方法学 · 统计学 2020-05-27 Carmen Armero

This study examines the application of Bayesian approach in the context of clinical trials, emphasizing their increasing importance in contemporary biomedical research. While conventional frequentist approach provides a foundational basis…

统计方法学 · 统计学 2026-01-16 Paramahansa Pramanik , Arnab Kumar Maity , Anjan Mandal , Haley Kate Robinson

Time-lapse seismic full-waveform inversion (FWI) provides estimates of dynamic changes in the subsurface by performing multiple seismic surveys at different times. Since FWI problems are highly non-linear and non-unique, it is important to…

地球物理 · 物理学 2023-08-21 Xin Zhang , Andrew Curtis

In healthcare, risk assessment of patient outcomes has been based on survival analysis for a long time, i.e. modeling time-to-event associations. However, conventional approaches rely on data from a single time-point, making them suboptimal…

机器学习 · 计算机科学 2026-02-20 Mine Öğretir , Miika Koskinen , Juha Sinisalo , Risto Renkonen , Harri Lähdesmäki

We consider the problem of inferring the values of an arbitrary set of variables (e.g., risk of diseases) given other observed variables (e.g., symptoms and diagnosed diseases) and high-dimensional signals (e.g., MRI images or EEG). This is…

机器学习 · 统计学 2019-02-07 Hao Wang , Chengzhi Mao , Hao He , Mingmin Zhao , Tommi S. Jaakkola , Dina Katabi

Accurate prediction of future agent trajectories is a critical challenge for ensuring safe and efficient autonomous navigation, particularly in complex urban environments characterized by multiple plausible future scenarios. In this paper,…

机器人学 · 计算机科学 2025-07-29 Haichuan Li , Tomi Westerlund

We present a new joint longitudinal and survival model aimed at estimating the association between the risk of an event and the change in and history of a biomarker that is repeatedly measured over time. We use cubic B-splines models for…

应用统计 · 统计学 2009-10-12 Elizabeth R. Brown

To extend cognitive diagnostic models (CDMs) to longitudinal settings, stepwise approaches that integrate a CDM model with a latent transition model and covariates are widely used due to their flexibility. Previous research has shown that…

统计方法学 · 统计学 2026-04-20 Yawen Ma , Anastasia Ushakova , Kate Cain , Gabriel Wallin

Bayes linear kinematics and Bayes linear Bayes graphical models provide an extension of Bayes linear methods so that full conditional updates may be combined with Bayes linear belief adjustment. In this paper we investigate the application…

统计方法学 · 统计学 2016-11-16 Kevin J. Wilson , Malcolm Farrow

A key question in clinical practice is accurate prediction of patient prognosis. To this end, nowadays, physicians have at their disposal a variety of tests and biomarkers to aid them in optimizing medical care. These tests are often…

In recent medical studies, the combination of longitudinal measurements with time-to-event data has increased the demand for more sophisticated models without unbiased estimates. Joint models for longitudinal and survival data have been…

统计方法学 · 统计学 2025-08-01 Dionisio Silva Neto , Denis Rustand , Haavard Rue , Danilo Alvares , Vera L. Tomazella

Joint modelling of longitudinal observations and event times continues to remain a topic of considerable interest in biomedical research. For example, in HIV studies, the longitudinal bio-marker such as CD4 cell count in a patient's blood…

统计方法学 · 统计学 2024-07-19 Srimanti Dutta , Arindom Chakraborty , Dipankar Bandyopadhyay

In this work, we propose a method for tracking multiple extended targets or unresolvable group targets in a clutter environment. Firstly, based on the Random Matrix Model (RMM), the joint state of the target is modeled as the Gamma Gaussian…

信号处理 · 电气工程与系统科学 2025-12-16 Yuanhao Cheng , Yunhe Cao , Tat-Soon Yeo , Yulin Zhang , Jie Fu