相关论文: Modeling Biological Multifunctionality with Echo S…

The echo state network (ESN) is a powerful and efficient tool for displaying dynamic data. However, many existing ESNs have limitations for properly modeling high-dimensional data. The most important limitation of these networks is the high…

Stochastic chemical systems with diffusion are modeled with a reaction-diffusion master equation. On a macroscopic level, the governing equation is a reaction-diffusion equation for the averages of the chemical species. On a mesoscopic…

In this paper we show the possibility of creating and identifying the features of an artificial neural network (ANN) which consists of mathematical models of biological neurons. The FitzHugh--Nagumo (FHN) system is used as an example of…

We present a mathematical study for the development of Multiple Sclerosis in which a spatio-temporal kinetic { theory} model describes, at the mesoscopic level, the dynamics of a high number of interacting agents. We consider both…

We study a system of nonlinear differential equations simulating transport phenomena in active media. The model we are interested in is a generalization of the celebrated FitzHugh-Nagumo system, describing the nerve impulse propagation in…

Experimental fMRI studies have shown that spontaneous brain activity i.e. in the absence of any external input, exhibit complex spatial and temporal patterns of co-activity between segregated brain regions. These so-called large-scale…

The stochastic FitzHugh-Nagumo (FHN) model is a two-dimensional nonlinear stochastic differential equation with additive degenerate noise, whose first component, the only one observed, describes the membrane voltage evolution of a single…

Diffusion-based and neural communication are two interesting domains in molecular communication. Both of them have distinct advantages and are exploited separately in many works. However, in some cases, neural and diffusion-based ways have…

Being an example for a relaxation oscillator, the FitzHugh-Nagumo model has been widely employed for describing the generation of action potentials. In this paper, we begin with a biological interpretation of what the subsequent…

This paper investigates the consensus problem for nonlinear heterogeneous multi-agent systems with limited communication data rate. Each agent is modeled by a higher-order strict-feedback continuous-time system with unknown nonlinearities…

Elastic network models (ENMs) are valuable and efficient tools for characterizing the collective internal dynamics of proteins based on the knowledge of their native structures. The increasing evidence that the biological functionality of…

Long-lead forecasting for spatio-temporal systems can often entail complex nonlinear dynamics that are difficult to specify it a priori. Current statistical methodologies for modeling these processes are often highly parameterized and thus,…

Here we demonstrate that the activity of neural ensembles can be quantitatively modeled. We first show that an ensemble dynamical model (EDM) accurately approximates the distribution of voltages and average firing rate per neuron of a…

We consider a spatially extended mean-field model of a FitzHugh-Nagumo neural network, with a rescaled interaction kernel. Our main purpose is to prove that its asymptotic limit in the regime of strong local interactions converges toward a…

Echo State Networks (ESN) are versatile recurrent neural network models in which the hidden layer remains unaltered during training. Interactions among nodes of this static backbone produce diverse representations of the given stimuli that…

Optimization of the stability of synchronized states between a pair of symmetrically coupled reaction-diffusion systems exhibiting rhythmic spatiotemporal patterns is studied in the framework of the phase reduction theory. The optimal…

Echo-State Networks (ESNs) distil a key neurobiological insight: richly recurrent but fixed circuitry combined with adaptive linear read-outs can transform temporal streams with remarkable efficiency. Yet fundamental questions about…

We analyze synchronization of relaxation oscillations in multiple-timescale reaction-diffusion systems. Interpreting synchronization as convergence to frequency-synchronized wave-train solutions, we resolve for the first time the case of…

Motivation: Agent-based modeling is an indispensable tool for studying complex biological systems. However, existing simulators do not always take full advantage of modern hardware and often have a field-specific software design. Results:…

Various biological system models have been proposed in systems biology, which are based on the complex biological reactions kinetic of various components. These models are not practical because we lack of kinetic information. In this paper,…