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Time series with non-uniform intervals occur in many applications, and are difficult to model using standard recurrent neural networks (RNNs). We generalize RNNs to have continuous-time hidden dynamics defined by ordinary differential…

机器学习 · 计算机科学 2019-07-10 Yulia Rubanova , Ricky T. Q. Chen , David Duvenaud

Modeling the time-series of high-dimensional, longitudinal data is important for predicting patient disease progression. However, existing neural network based approaches that learn representations of patient state, while very flexible, are…

机器学习 · 计算机科学 2021-06-21 Zeshan Hussain , Rahul G. Krishnan , David Sontag

Inspired by the ubiquitous use of differential equations to model continuous dynamics across diverse scientific and engineering domains, we propose a novel and intuitive approach to continuous sequence modeling. Our method interprets…

机器学习 · 计算机科学 2025-02-03 Macheng Shen , Chen Cheng

Reasoning about graphs evolving over time is a challenging concept in many domains, such as bioinformatics, physics, and social networks. We consider a common case in which edges can be short term interactions (e.g., messaging) or long term…

机器学习 · 统计学 2020-06-22 Boris Knyazev , Carolyn Augusta , Graham W. Taylor

Deep neural networks (DNNs), while increasingly deployed in many applications, struggle with robustness against anomalous and out-of-distribution (OOD) data. Current OOD benchmarks often oversimplify, focusing on single-object tasks and not…

计算机视觉与模式识别 · 计算机科学 2024-09-30 Debargha Ganguly , Debayan Gupta , Vipin Chaudhary

Major depressive disorder (MDD) is a common neuropsychiatric condition whose accurate diagnosis from resting-state functional magnetic resonance imaging (rs-fMRI) remains difficult. Dynamic functional connectivity (DFC) captures…

计算机视觉与模式识别 · 计算机科学 2026-05-26 Muhammad Asif Hasan , Yanming Zhu , Xuefei Yin , Alan Wee-Chung Liew

Diabetic retinopathy (DR), affecting millions globally with projections indicating a significant rise, poses a severe blindness risk and strains healthcare systems. Diagnostic complexity arises from visual symptom overlap with conditions…

图像与视频处理 · 电气工程与系统科学 2026-01-14 Susmita Kar , A S M Ahsanul Sarkar Akib , Abdul Hasib , Samin Yaser , Anas Bin Azim

Sequential recommendation (SR) is widely deployed in e-commerce platforms, streaming services, etc., revealing significant potential to enhance user experience. However, existing methods often overlook two critical factors: irregular user…

信息检索 · 计算机科学 2025-11-25 Haoyan Fu , Zhida Qin , Shixiao Yang , Haoyao Zhang , Bin Lu , Shuang Li , Tianyu Huang , John C. S. Lui

Electronic health records contain valuable information for monitoring patients' health trajectories over time. Disease progression models have been developed to understand the underlying patterns and dynamics of diseases using these data as…

Increasing the layer number of on-chip photonic neural networks (PNNs) is essential to improve its model performance. However, the successively cascading of network hidden layers results in larger integrated photonic chip areas. To address…

机器学习 · 计算机科学 2023-02-08 Yun Zhao , Hang Chen , Min Lin , Haiou Zhang , Tao Yan , Xing Lin , Ruqi Huang , Qionghai Dai

Control of blood glucose is essential for diabetes management. Current digital therapeutic approaches for subjects with Type 1 diabetes mellitus (T1DM) such as the artificial pancreas and insulin bolus calculators leverage machine learning…

计算机视觉与模式识别 · 计算机科学 2019-02-27 Kezhi Li , John Daniels , Chengyuan Liu , Pau Herrero , Pantelis Georgiou

People with diabetes have to manage their blood glucose level to keep it within an appropriate range. Predicting whether future glucose values will be outside the healthy threshold is of vital importance in order to take corrective actions…

机器学习 · 计算机科学 2023-04-03 J. Alvarado , J. Manuel Velasco , F. Chávez , J. Ignacio Hidalgo , F. Fernández de Vega

Hyperkinetic movement disorders (HMDs) such as dystonia, tremor, chorea, myoclonus, and tics are disabling motor manifestations across childhood and adulthood. Their fluctuating, intermittent, and frequently co-occurring expressions hinder…

Neural Ordinary Differential Equations model dynamical systems with ODEs learned by neural networks. However, ODEs are fundamentally inadequate to model systems with long-range dependencies or discontinuities, which are common in…

机器学习 · 计算机科学 2022-06-15 Samuel Holt , Zhaozhi Qian , Mihaela van der Schaar

Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insufficient insulin production or impaired insulin utilization. One of its most severe complications is diabetic retinopathy (DR), a…

图像与视频处理 · 电气工程与系统科学 2026-02-12 Ali El Bellaj , Aya Benradi , Salman El Youssoufi , Taha El Marzouki , Mohammed-Amine Cheddadi

The neural ordinary differential equation (ODE) framework has emerged as a powerful tool for developing accelerated surrogate models of complex physical systems governed by partial differential equations (PDEs). A popular approach for PDE…

流体动力学 · 物理学 2025-03-26 Ashish S. Nair , Shivam Barwey , Pinaki Pal , Jonathan F. MacArt , Troy Arcomano , Romit Maulik

The intersection of machine learning and dynamical systems has generated considerable interest recently. Neural Ordinary Differential Equations (NODEs) represent a rich overlap between these fields. In this paper, we develop a continuous…

Chronic kidney disease (CKD) is a gradual loss of renal function over time, and it increases the risk of mortality, decreased quality of life, as well as serious complications. The prevalence of CKD has been increasing in the last couple of…

机器学习 · 计算机科学 2020-11-18 Jinghe Zhang , Kamran Kowsari , Mehdi Boukhechba , James Harrison , Jennifer Lobo , Laura Barnes

This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…

机器学习 · 计算机科学 2025-11-07 Anzhuo Xie , Wei-Chen Chang

Purpose: To develop a neural ordinary differential equation (ODE) model for visualizing deep neural network (DNN) behavior during multi-parametric MRI (mp-MRI) based glioma segmentation as a method to enhance deep learning explainability.…

定量方法 · 定量生物学 2022-03-25 Zhenyu Yang , Zongsheng Hu , Hangjie Ji , Kyle Lafata , Scott Floyd , Fang-Fang Yin , Chunhao Wang